{"id":1642,"date":"2020-10-28T13:20:06","date_gmt":"2020-10-28T17:20:06","guid":{"rendered":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/?post_type=dt_team&#038;p=1642"},"modified":"2023-09-25T13:00:07","modified_gmt":"2023-09-25T17:00:07","slug":"dr-nivia-l-perez","status":"publish","type":"dt_team","link":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/dt_team\/dr-nivia-l-perez\/","title":{"rendered":"P\u00e9rez, Nivia L., PhD"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-316569dff587f3729\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-316569dff587f3729 uvc-5033 accent-subtitle-color\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-316569dff587f3729 h2'  data-responsive-json-new='{\"font-size\":\"desktop:30px;mobile_landscape:34px;\",\"line-height\":\"desktop:40px;mobile_landscape:44px;\"}' ><h2 style=\"font-weight:bold;color:#0a0a0a;margin-bottom:10px;\">P\u00e9rez, Nivia L., PhD<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-316569dff587f3729 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"desktop:18px;mobile_landscape:20px;\",\"line-height\":\"desktop:34px;mobile_landscape:30px;\"}'  style=\"font-weight:bold;margin-bottom:30px;\">Professor<\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;]<div class=\"ult-content-box-container \" >\t\t<div class=\"ult-content-box\" style=\"background-color:#545454;box-shadow: px px px px none;border-style:solid;border-width:5px;border-radius:5px;border-color:#545454;padding:10px;-webkit-transition: all 700ms ease;-moz-transition: all 700ms ease;-ms-transition: all 700ms ease;-o-transition: all 700ms ease;transition: all 700ms ease;\"  data-hover_box_shadow=\"none\"     data-bg=\"#545454\"  data-border_color=\"#545454\" ><style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-e4fb4089903a8ccf15c722cc6b116baa.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-e4fb4089903a8ccf15c722cc6b116baa.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-e4fb4089903a8ccf15c722cc6b116baa .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-e4fb4089903a8ccf15c722cc6b116baa .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-e4fb4089903a8ccf15c722cc6b116baa alignnone  enable-bg-rollover dt-icon-bg-off\" style=\"margin-top:0px; margin-bottom:0px; margin-left:0px; margin-right:0px; width:300px;\"><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20300%20300&#39;%2F%3E\" data-src=\"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-content\/uploads\/sites\/23\/2020\/10\/drniviaperez.jpg\" data-srcset=\"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-content\/uploads\/sites\/23\/2020\/10\/drniviaperez.jpg 300w\" loading=\"eager\" sizes=\"(max-width: 300px) 100vw, 300px\" width=\"300\" height=\"300\"  data-dt-location=\"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/dt_team\/dr-nivia-l-perez\/drniviaperez\/\" style=\"--ratio: 300 \/ 300;\" alt=\"Dr. Nivia L. P\u00e9rez\" \/><\/div><\/div><\/div>[vc_empty_space][vc_column_text]<span style=\"color: #ffffff;\"><strong>Contact Info<\/strong><\/span>[\/vc_column_text]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-5617\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-mail-03\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-5617 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"mailto:nivia.perez@upr.edu\">nivia.perez@upr.edu<\/a><\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-6144\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-05\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-6144 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">Dr. Guillermo Arbona Irizarry Bldg.<\/span><br \/>\n<span style=\"color: #ffffff;\">Lab A556\/A557\/A558<\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-6174\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-phone-071\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-6174 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">787-758-2525 x1512<\/span><\/span><\/div><\/li><\/ul><\/div>\t\t<\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-655769dff5880022a\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-655769dff5880022a uvc-8536  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-655769dff5880022a h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">Research Interests<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-655769dff5880022a .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Role of glutamate&#8217;s metabotropic receptors in the mechanisms underlying anxiety and the establishment of emotional memory in females.<\/p>\n<p>We investigate the role of metabotropic glutamate receptors (mGluRs) in anxiety-related behaviors and emotional memory at the cellular and behavioral level. Anxiolytics are one of the most prescribed and abused medications in the U.S. Females are twice as likely to develop anxiety disorders than males, suggesting that gonadal hormones play a role in the etiology of anxiety-related behaviors. Understanding the contribution of sex steroids in modulating anxiety and emotional memory and how males and females respond to pharmacotherapy is of relevance for the treatment of anxiety-related disorders and is the major focus of the research carried out in our laboratory. We perform different behavioral tests, such as the light and dark, the elevated plus maze, the voguel conflict test and the passive avoidance task to elucidate the role of group I mGluR agonists in the basolateral amygdala. For the cellular\/molecular approach we perform immunohistochemistry and western blot analysis to study protein levels of group I mGluRs as well as to study if there is colocalization between estrogen and mGluR receptors.<\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-556769dff58800293\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-556769dff58800293 uvc-5091  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-556769dff58800293 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">Present Funding<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-556769dff58800293 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Med Sci Campus, School of Medicine Associate Deanship for Biomedical Sciences<\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-74069dff588002f0\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-74069dff588002f0 uvc-3439  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-74069dff588002f0 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">Selected Publications<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-74069dff588002f0 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><\/p>\n<ul>\n<li><em>De Jes\u00fas-Burgos MI*,<\/em> Gonz\u00e1lez-Garc\u00eda S, Cruz-Santa Y, <strong>P\u00e9rez-Acevedo NL<\/strong> (2016) Amygdalar activation of group I metabotropic glutamate receptors produces anti- and pro-conflict effects depending upon animal sex in a sexually dimorphic conditioned conflicto-based anxiety model. Behav Brain Res 302:200-212<\/li>\n<li>Ramos-Pratts K*, Rosa-Gonz\u00e1lez D, <strong>P\u00e9rez-Acevedo NL<\/strong>, Cintr\u00f3n-L\u00f3pez D, Barreto-Estrada JL (2013) Sex-specific effect of the anabolic steroid, 17\u03b1-methyltestosterone, on inhibitory avoidance learning in periadolescent rats. Behav Processes. 99:73-80.<\/li>\n<li>De Jes\u00fas-Burgos MI, Torres-Llenza V, <strong>P\u00e9rez-Acevedo, NL<\/strong> (2012) Activation of amygdalar metabotropic glutamate receptors modulates anxiety and risk assessment behaviors in ovariectomized estradiol-treated female rats. Pharmacol Biochem Behav 101(3):369-378.<\/li>\n<li><strong>P\u00e9rez-Acevedo NL<\/strong>, Lathroum LP, Jorge JC (2006) Sex-specific modulation of affect after infusion of the neurosteroid 3\u03b1DIOL in the basolateral amygdala; Behav Neurosci. Jun;120(3):632-640.<\/li>\n<li><strong>P\u00e9rez Acevedo NL<\/strong>, Krenz WD (2005) Metabotropic glutamate receptor agonists modify the pyloric output of the crustacean stomatogastric ganglion, Brain Res. 1662(1-2): 1-8.<\/li>\n<li>Krenz WD, Nguyen D, <strong>P\u00e9rez-Acevedo NL<\/strong>, Selverston AI (2000) Group I, II, and III mGluR compounds affect rhythm generation in the gastric circuit of the crustacean stomatogastric ganglion<em>.\u00a0 <\/em><em>J Neurophysiol.<\/em> Mar;83(3):1188-201.<\/li>\n<li><strong>P\u00e9rez-Acevedo NL<\/strong>, Marrero H, del Castillo J, Smith DS (1998) Transient wrinkles in a variable length tendon.\u00a0 In: R. Mooi and M. Telford, <em>Echinoderms: San Francisco<\/em>.\u00a0 A.A. Balkema, Rotherdan, Netherlands, pp. 783-790.<\/li>\n<li>del Castillo J, Hime J, <strong>P\u00e9rez-Acevedo N<\/strong> (1998) A short history of electrophysiology and its techniques.\u00a0 Section III. Electrophysiological instruments and techniques.\u00a0 <em>PRHSJ.<\/em> 17 (1): 81-88.<\/li>\n<li><strong>P\u00e9rez N<\/strong>, Sosa MA, Kuffler DP (1997) Growth cones turn up concentration gradients of diffusible peripheral target-derived factors.\u00a0 <em>Exp. Neurol<\/em>. 145: 196-202.<\/li>\n<\/ul>\n<p><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_empty_space][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":1936,"comment_status":"closed","ping_status":"closed","template":"","dt_team_category":[26],"class_list":["post-1642","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-professor","dt_team_category-26","description-off"],"aioseo_notices":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/dt_team\/1642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/types\/dt_team"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/comments?post=1642"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/media\/1936"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/media?parent=1642"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/anatomyneurobiology\/wp-json\/wp\/v2\/dt_team_category?post=1642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}