{"id":1033,"date":"2021-11-01T14:09:37","date_gmt":"2021-11-01T18:09:37","guid":{"rendered":"https:\/\/md.rcm.upr.edu\/biochemistry\/?post_type=dt_team&#038;p=1033"},"modified":"2023-12-06T07:38:58","modified_gmt":"2023-12-06T11:38:58","slug":"dr-nataliya-chorna","status":"publish","type":"dt_team","link":"https:\/\/md.rcm.upr.edu\/biochemistry\/dt_team\/dr-nataliya-chorna\/","title":{"rendered":"Dr. Nataliya Chorna"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-798369d25101dc13c\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-798369d25101dc13c uvc-3039 accent-subtitle-color\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-798369d25101dc13c h2'  data-responsive-json-new='{\"font-size\":\"desktop:30px;mobile_landscape:34px;\",\"line-height\":\"desktop:40px;mobile_landscape:44px;\"}' ><h2 style=\"font-weight:bold;color:#0a0a0a;margin-bottom:10px;\">Dr. Nataliya Chorna<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-798369d25101dc13c .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"desktop:18px;mobile_landscape:20px;\",\"line-height\":\"desktop:34px;mobile_landscape:30px;\"}'  style=\"font-weight:bold;margin-bottom:30px;\">Assistant Professor<\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;]<div class=\"ult-content-box-container \" >\t\t<div class=\"ult-content-box\" style=\"background-color:#545454;box-shadow: px px px px none;border-style:solid;border-width:5px;border-radius:5px;border-color:#545454;padding:10px;-webkit-transition: all 700ms ease;-moz-transition: all 700ms ease;-ms-transition: all 700ms ease;-o-transition: all 700ms ease;transition: all 700ms ease;\"  data-hover_box_shadow=\"none\"     data-bg=\"#545454\"  data-border_color=\"#545454\" ><style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-eec05c853c444ed6e88259e5d5ad9238.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-eec05c853c444ed6e88259e5d5ad9238.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-eec05c853c444ed6e88259e5d5ad9238 .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-eec05c853c444ed6e88259e5d5ad9238 .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-eec05c853c444ed6e88259e5d5ad9238 alignnone  enable-bg-rollover dt-icon-bg-off\" style=\"margin-top:0px; margin-bottom:0px; margin-left:0px; margin-right:0px; width:300px;\"><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20300%20300&#39;%2F%3E\" data-src=\"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-content\/uploads\/sites\/24\/2021\/11\/NATALIYA-CHORNA-1.jpg\" data-srcset=\"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-content\/uploads\/sites\/24\/2021\/11\/NATALIYA-CHORNA-1.jpg 300w\" loading=\"eager\" sizes=\"(max-width: 300px) 100vw, 300px\" width=\"300\" height=\"300\"  data-dt-location=\"https:\/\/md.rcm.upr.edu\/biochemistry\/dt_team\/dr-nataliya-chorna\/nataliya-chorna-2\/\" style=\"--ratio: 300 \/ 300;\" alt=\"Dr. Nataliya Chorna\" \/><\/div><\/div><\/div>[vc_empty_space][vc_column_text]<span style=\"color: #ffffff;\"><strong>Contact Info<\/strong><\/span>[\/vc_column_text]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-3691\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-mail-03\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-3691 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"mailto:nataliya.chorna@upr.edu\">nataliya.chorna@upr.edu<\/a><\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-3481\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-05\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-3481 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Director PR-INBRE Metabolomics Research Core,<\/span><br \/>\n<span style=\"color: #ffffff;\">Lab A632 6th Floor<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico\u200b<\/span><br \/>\n<span style=\"color: #ffffff;\">Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">San Juan, PR 00935<\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-8997\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-phone-071\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-8997 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Tel (787) 758-2525 ext 1640<\/span><\/p>\n<p><span style=\"color: #ffffff;\">Fax (787)764-8209<\/span><\/span><\/div><\/li><\/ul><\/div>[vc_column_text]<span style=\"color: #ffffff;\"><strong>Education<\/strong><\/span>[\/vc_column_text]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><span style=\"color: #ffffff;\">Doctorate in Biology with a specialty in Microbiology, 1987<\/span><br \/>\n<span style=\"color: #ffffff;\">National Academy of Sciences of Ukraine, Kyiv, Ukraine<\/span><\/li>\n<li><span style=\"color: #ffffff;\">MS Master Degree in Biochemistry, 1979<\/span><br \/>\n<span style=\"color: #ffffff;\">Taras Shevchenko National University of Kyiv, Kyiv, Ukraine<\/span><\/li>\n<\/ul>\n<\/div>\t\t<\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-238769d25101e0266\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-238769d25101e0266 uvc-1991  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-238769d25101e0266 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">PR-INBRE Metabolomics Research Core<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-238769d25101e0266 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">As the director of the PR-INBRE-Metabolomics Research Core, I provide extensive services in metabolomics for investigators and students in Puerto Rico and beyond, including methods development, scientific seminars, and training workshops.<\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-574569d25101e02bd\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-574569d25101e02bd uvc-1245  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-574569d25101e02bd h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">Research Interests<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-574569d25101e02bd .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">The long-term goal of my research is to understand how shifts within metabolic pathways in response to changes in lifestyle contribute to human health and disease. I apply integrated multi-omics approaches to study host-microbiome\/metabolome interaction to develop a basis for new diagnostic aids and therapeutic interventions.<\/div><\/div>[vc_empty_space]<div id=\"advanced-tabs-desc-wrap-6597\" class=\"ult_tabs \" style=\" \" data-tabsstyle=\"style1\"\n data-titlebg=\"#e7ecea\" data-titlecolor=\"#74777b\" data-fullheight=\"off\"\n data-titlehoverbg=\"#4f90d1\" data-titlehovercolor=\"#ffffff\"\n data-rotatetabs=\"0\" data-responsivemode=\"Both\" data-animation=\"Slide\"\ndata-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#4f90d1\"  data-respmode=\"Tabs\" data-respwidth=\"400\" data-scroll = \"on\" data-activeindex=\"1\"><ul id=advanced-tabs-wrap-9375 class=\"ult_tabmenu style1 Style_4\" style=\"color:transparent;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-width:0px;\"><li class=\"ult_tab_li ult_tab_style_4  \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;border-color:transparent;border-width:0px;border-style:solid;border-top-left-radius:8px;\">\n\t\t\t\t\t<a href=\"#1570547655326-2-7\" id=\"1570547655326-2-7\" style=\"color:#74777b;;  \" class=\"ult_a \">\n\t\t\t\t\t   <span class=\"ult_tab_main  Both \">\n\t\t\t\t\t    <span class=\"ult_tab_section\">\n\t\t\t\t\t  \t\t<span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult-responsive\" style=\"\">PR-INBRE MRC<\/span>\n\t\t\t\t\t\t   \t<span class=\"aio-icon none ult_tab_iconright\" style=\"color:#74777b;font-size:15px;\">\n\t\t\t\t\t\t   \t<i class=\"   ult_tab_icon\"  ><\/i>\n\t\t\t\t\t\t   <\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t   <\/span>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li ult_tab_style_4  \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;border-color:transparent;border-width:0px;border-style:solid;\">\n\t\t\t\t\t<a href=\"#1570547730782-3-6\" id=\"1570547730782-3-6\" style=\"color:#74777b;;  \" class=\"ult_a \">\n\t\t\t\t\t   <span class=\"ult_tab_main  Both \">\n\t\t\t\t\t    <span class=\"ult_tab_section\">\n\t\t\t\t\t  \t\t<span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult-responsive\" style=\"\">PROJECTS<\/span>\n\t\t\t\t\t\t   \t<span class=\"aio-icon none ult_tab_iconright\" style=\"color:#74777b;font-size:15px;\">\n\t\t\t\t\t\t   \t<i class=\"   ult_tab_icon\"  ><\/i>\n\t\t\t\t\t\t   <\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t   <\/span>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li ult_tab_style_4  \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;border-color:transparent;border-width:0px;border-style:solid;border-top-right-radius:8px;\">\n\t\t\t\t\t<a href=\"#1570556815923-4-4\" id=\"1570556815923-4-4\" style=\"color:#74777b;;  \" class=\"ult_a \">\n\t\t\t\t\t   <span class=\"ult_tab_main  Both \">\n\t\t\t\t\t    <span class=\"ult_tab_section\">\n\t\t\t\t\t  \t\t<span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult-responsive\" style=\"\">CHORNA LAB<\/span>\n\t\t\t\t\t\t   \t<span class=\"aio-icon none ult_tab_iconright\" style=\"color:#74777b;font-size:15px;\">\n\t\t\t\t\t\t   \t<i class=\"   ult_tab_icon\"  ><\/i>\n\t\t\t\t\t\t   <\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t   <\/span>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><\/ul><div  data-ultimate-target='#advanced-tabs-desc-wrap-6597 .ult_tabcontent .ult_tab_min_contain  p'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' class=\"ult_tabcontent ult-responsive style1\" style=\"color:#74777b;\"><div class=\"ult_tab_min_contain \" >\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1047&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1048&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1049&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1050&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_column_text]<span class=\" gBYvFf\">RR-INBRE Metabolomics Research Core (MRC) was established by the Puerto Rico IDeA Network Biomedical Research Excellence (PRINBRE) in the fall of 2011 and Dr. Nataliya Chorna has been serving as the core director since its establishment. PRINBRE is a program inspired by the National Institutes of Health Institutional Developmental Awards: IDeA Networks of Biomedical Research Excellence (INBRE). MRC is the only one of its kind in Puerto Rico and has significantly enhanced the competitiveness of biomedical researchers at Puerto Rico academic institutions.<\/span><span class=\" gBYvFf\">\u00a0<\/span><span class=\" gBYvFf\">The MRC is located at the Department of Biochemistry, University of Puerto Rico, Medical Science Campus. The MRC is equipped with modern instrumentation including Agilent Seahorse XF96 Metabolic scanner and gas chromatography\/mass spectrometry instrumentation such as single quadrupole GC\/MS QP2010 and triple quadrupole GC\/MS\/MS TQ8050 (Shimadzu Inc) equipped with two comprehensive databases such as the NIST14\/2014\/EPA\/NIH database and 11th edition of Willy Registry database that contains a fully evaluated collection of electron ionization (EI) mass spectra of over 267,376 and 700,000 chemical compounds correspondently, as well as a small appliances for metabolites extraction and derivatization. As a coordinator of the facility, Dr. Chorna provides research and training support to the Puerto Rico biomedical research community with the aim to address the needs for increasing metabolomics research capacity by (1) offering specialized supporting service for an assay development for specific metabolites identification; (2) providing training and knowledge dissemination among researchers, undergraduate and graduate students in Puerto Rico, and (3) support established and new collaborations that exploit metabolomics approaches to move basic and clinical research towards translational goals. The MRC long term goal is to increase the number of investigators cross-trained in metabolomics, bioinformatics analysis, biochemistry, and physiology providing the access to modern state-of-the-art analytical tools for large-scale metabolic profiling and services related to metabolomics research to academia, government and industry in Puerto Rico and abroad.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner]<div id=\"ultimate-heading-814169d25101e2c9a\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-814169d25101e2c9a uvc-9313  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-814169d25101e2c9a h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">TRAINING WORKSHOPS AND SEMINARS<\/h3><\/div><\/div>[vc_media_grid grid_id=&#8221;vc_gid:1700152329988-a910f6e9-492c-8&#8243; include=&#8221;1051,1052,1053,1054,1055,1056,1057,1058,1059,1060,1061,1062,1063,1064,1065&#8243;][\/vc_column_inner][\/vc_row_inner]\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1066&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-603269d25101e2ece\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-603269d25101e2ece uvc-1198  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-603269d25101e2ece h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">EFFECTS OF RUNNING EXERCISE ON THE REGULATION OF TRYPTOPHAN METABOLISM ALONG THE MICROBIOTA-GUT-BRAIN AXIS<\/h3><\/div><\/div>[vc_column_text]<span class=\" gBYvFf\">This is a pilot project funded by the\u00a0<\/span><span class=\" gBYvFf\">Deanship for Research University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.<\/span><span class=\" gBYvFf\">\u00a0The main objective of this application is to address the recent interest by basic and clinical studies on tryptophan metabolism, which is directly or indirectly controlled by the gut microbiota. The gut microbial influence on tryptophan metabolism emerges as an important driving force at multiple levels of the gut-brain axis contributing to brain health. This proposal poses to address the effects of running exercise using mice model on diversification of gut microbiota and its endogenous capacity to boost tryptophan metabolism in the brain via the serotonin pathway and provide directions toward designing microbiome\/metabolome-based diagnostics and therapeutic approaches for the central nervous system disorders.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1067&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-702769d25101e2f0f\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-702769d25101e2f0f uvc-4476  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-702769d25101e2f0f h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">HIGH-RESOLUTION META-OMICS APPROACHES TO STUDY CERVICAL HPV INFECTIONS FOR CANCER PREVENTION<\/h3><\/div><\/div>[vc_column_text]<\/p>\n<section id=\"h.3e1d518780a900_38\" class=\"yaqOZd\">\n<div class=\"mYVXT\">\n<div class=\"LS81yb VICjCf\" tabindex=\"-1\">\n<div class=\"hJDwNd-AhqUyc-qWD73c purZT-AhqUyc-II5mzb pSzOP-AhqUyc-qWD73c JNdkSc\">\n<div class=\"JNdkSc-SmKAyb\">\n<div class=\"\">\n<div class=\"oKdM2c Kzv0Me\">\n<div id=\"h.3e1d518780a900_46\" class=\"hJDwNd-AhqUyc-qWD73c jXK9ad D2fZ2 OjCsFc wHaque GNzUNc\">\n<div class=\"jXK9ad-SmKAyb\">\n<div class=\"tyJCtd mGzaTb baZpAe\">\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\"><span class=\" gBYvFf\">Collaborative project with Filipa Godoy Vitorino, PhD, UPR-MSC. In this project we integrate next-generation sequencing data with ecology, physiology, metagenomics, metabolomics and bioinformatics to evaluate the metabolic capacity, and activity of the human microbiome among Puerto Rican women diagnosed with human papillomavirus (HPV) infections and to predict the occurrence of metabolic abnormalities that could lead to cervical cancer development (PMC7235793; PMC7022855; PMC6310238). The long-term goal of this project is to predict the microbiome activity and dynamics for development of new pharmaceutic strategies directed on modification the microbiome and its metabolic phenotype in health and disease.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"h.2464114a461351d6_0\" class=\"yaqOZd\"><\/section>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1068&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-206469d25101e2f4a\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-206469d25101e2f4a uvc-2010  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-206469d25101e2f4a h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">DISCOVERY OF THE BIOLOGICAL FUNCTIONS OF MECHANOSENSOR MTL1P OF SACCHAROMYCES CEREVISIAE THROUGH COMPREHENSIVE OMICS ANALYSIS<\/h3><\/div><\/div>[vc_column_text]<\/p>\n<section id=\"h.3e1d518780a900_38\" class=\"yaqOZd\">\n<div class=\"mYVXT\">\n<div class=\"LS81yb VICjCf\" tabindex=\"-1\">\n<div class=\"hJDwNd-AhqUyc-qWD73c purZT-AhqUyc-II5mzb pSzOP-AhqUyc-qWD73c JNdkSc\">\n<div class=\"JNdkSc-SmKAyb\">\n<div class=\"\">\n<div class=\"oKdM2c Kzv0Me\">\n<div id=\"h.3e1d518780a900_46\" class=\"hJDwNd-AhqUyc-qWD73c jXK9ad D2fZ2 OjCsFc wHaque GNzUNc\">\n<div class=\"jXK9ad-SmKAyb\">\n<div class=\"tyJCtd mGzaTb baZpAe\">\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\"><span class=\" gBYvFf\"> Collaborative project with Jose Rodriguez Medina, PhD, UPR-MSC. We identify a novel role for mechanosensor Mtl1p of<\/span><span class=\" gBYvFf\"><em> Saccharomyces cerevisiae<\/em><\/span><span class=\" gBYvFf\"> in complex cellular regulatory mechanisms required to maintain cellular homeostasis using integrative multi-omics analysis of the cellular transcriptome, proteome, metabolome and functional enrichment analyses (PMC8016984).<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"h.2464114a461351d6_0\" class=\"yaqOZd\"><\/section>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner]\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space]<div id=\"ultimate-heading-569369d25101e307f\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-569369d25101e307f uvc-6379  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"center\" style=\"text-align:center\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-569369d25101e307f h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">MEET THE TEAM<\/h3><\/div><\/div>[vc_media_grid element_width=&#8221;3&#8243; item=&#8221;mediaGrid_BorderedScaleWithTitle&#8221; grid_id=&#8221;vc_gid:1700152329990-77e4f5e4-0133-10&#8243; include=&#8221;1069,1070,1071,1072,1073,1074,1075&#8243;]\n\t\t\t<\/div><\/div><\/div><\/div><div class=\"ult_acord advanced-tabs-desc-wrap-6597\">\n   <div class=\"ult-tabto-accordion \" style=\"width:;\"\n    data-titlecolor=\"#74777b\"  data-titlebg=\"#e7ecea\"\n     data-titlehoverbg=\"#4f90d1\" data-titlehovercolor=\"#ffffff\" data-animation=\"Slide\"\n     data-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#4f90d1\" data-scroll = \"on\" data-activeindex=\"1\" >\n     <dl><dt class=\"\">\n        \t<a class=\"ult-tabto-actitle withBorder ult_a\" id=\"1570547655326-2-7\" style=\"color:#74777b;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1570547655326-2-7\">\n        \t\t<i class=\"accordion-icon\"><\/i>\n        \t\t\t<span class=\"ult_tab_main ult_ac_mainBoth\">\n\t\t\t\t\t   <span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult_acordian-text ult-responsive\" style=\";color:inherit \" >PR-INBRE MRC<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t   <div class=\"aio-icon none \" style=\"color:#74777b;font-size:15px;\" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\">\n\t\t\t\t\t   <i class=\"    ult_tab_icon\"  ><\/i>\n\t\t\t\t\t   <\/div>\n\t\t\t\t\t<\/a><\/dt>\n            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t               [vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1047&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1048&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1049&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;1050&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_column_text]<span class=\" gBYvFf\">RR-INBRE Metabolomics Research Core (MRC) was established by the Puerto Rico IDeA Network Biomedical Research Excellence (PRINBRE) in the fall of 2011 and Dr. Nataliya Chorna has been serving as the core director since its establishment. PRINBRE is a program inspired by the National Institutes of Health Institutional Developmental Awards: IDeA Networks of Biomedical Research Excellence (INBRE). MRC is the only one of its kind in Puerto Rico and has significantly enhanced the competitiveness of biomedical researchers at Puerto Rico academic institutions.<\/span><span class=\" gBYvFf\">\u00a0<\/span><span class=\" gBYvFf\">The MRC is located at the Department of Biochemistry, University of Puerto Rico, Medical Science Campus. The MRC is equipped with modern instrumentation including Agilent Seahorse XF96 Metabolic scanner and gas chromatography\/mass spectrometry instrumentation such as single quadrupole GC\/MS QP2010 and triple quadrupole GC\/MS\/MS TQ8050 (Shimadzu Inc) equipped with two comprehensive databases such as the NIST14\/2014\/EPA\/NIH database and 11th edition of Willy Registry database that contains a fully evaluated collection of electron ionization (EI) mass spectra of over 267,376 and 700,000 chemical compounds correspondently, as well as a small appliances for metabolites extraction and derivatization. As a coordinator of the facility, Dr. Chorna provides research and training support to the Puerto Rico biomedical research community with the aim to address the needs for increasing metabolomics research capacity by (1) offering specialized supporting service for an assay development for specific metabolites identification; (2) providing training and knowledge dissemination among researchers, undergraduate and graduate students in Puerto Rico, and (3) support established and new collaborations that exploit metabolomics approaches to move basic and clinical research towards translational goals. The MRC long term goal is to increase the number of investigators cross-trained in metabolomics, bioinformatics analysis, biochemistry, and physiology providing the access to modern state-of-the-art analytical tools for large-scale metabolic profiling and services related to metabolomics research to academia, government and industry in Puerto Rico and abroad.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner]<div id=\"ultimate-heading-119569d25101e228d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-119569d25101e228d uvc-6757  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-119569d25101e228d h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">TRAINING WORKSHOPS AND SEMINARS<\/h3><\/div><\/div>[vc_media_grid grid_id=&#8221;vc_gid:1700152329988-a910f6e9-492c-8&#8243; include=&#8221;1051,1052,1053,1054,1055,1056,1057,1058,1059,1060,1061,1062,1063,1064,1065&#8243;][\/vc_column_inner][\/vc_row_inner]\n\t\t\t            <\/div>\n        \t<\/dd><dt class=\"\">\n        \t<a class=\"ult-tabto-actitle withBorder ult_a\" id=\"1570547730782-3-6\" style=\"color:#74777b;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1570547730782-3-6\">\n        \t\t<i class=\"accordion-icon\"><\/i>\n        \t\t\t<span class=\"ult_tab_main ult_ac_mainBoth\">\n\t\t\t\t\t   <span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult_acordian-text ult-responsive\" style=\";color:inherit \" >PROJECTS<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t   <div class=\"aio-icon none \" style=\"color:#74777b;font-size:15px;\" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\">\n\t\t\t\t\t   <i class=\"    ult_tab_icon\"  ><\/i>\n\t\t\t\t\t   <\/div>\n\t\t\t\t\t<\/a><\/dt>\n            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t               [vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1066&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-882969d25101e2370\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-882969d25101e2370 uvc-4601  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-882969d25101e2370 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">EFFECTS OF RUNNING EXERCISE ON THE REGULATION OF TRYPTOPHAN METABOLISM ALONG THE MICROBIOTA-GUT-BRAIN AXIS<\/h3><\/div><\/div>[vc_column_text]<span class=\" gBYvFf\">This is a pilot project funded by the\u00a0<\/span><span class=\" gBYvFf\">Deanship for Research University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.<\/span><span class=\" gBYvFf\">\u00a0The main objective of this application is to address the recent interest by basic and clinical studies on tryptophan metabolism, which is directly or indirectly controlled by the gut microbiota. The gut microbial influence on tryptophan metabolism emerges as an important driving force at multiple levels of the gut-brain axis contributing to brain health. This proposal poses to address the effects of running exercise using mice model on diversification of gut microbiota and its endogenous capacity to boost tryptophan metabolism in the brain via the serotonin pathway and provide directions toward designing microbiome\/metabolome-based diagnostics and therapeutic approaches for the central nervous system disorders.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1067&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-654569d25101e23b7\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-654569d25101e23b7 uvc-4915  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-654569d25101e23b7 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">HIGH-RESOLUTION META-OMICS APPROACHES TO STUDY CERVICAL HPV INFECTIONS FOR CANCER PREVENTION<\/h3><\/div><\/div>[vc_column_text]<\/p>\n<section id=\"h.3e1d518780a900_38\" class=\"yaqOZd\">\n<div class=\"mYVXT\">\n<div class=\"LS81yb VICjCf\" tabindex=\"-1\">\n<div class=\"hJDwNd-AhqUyc-qWD73c purZT-AhqUyc-II5mzb pSzOP-AhqUyc-qWD73c JNdkSc\">\n<div class=\"JNdkSc-SmKAyb\">\n<div class=\"\">\n<div class=\"oKdM2c Kzv0Me\">\n<div id=\"h.3e1d518780a900_46\" class=\"hJDwNd-AhqUyc-qWD73c jXK9ad D2fZ2 OjCsFc wHaque GNzUNc\">\n<div class=\"jXK9ad-SmKAyb\">\n<div class=\"tyJCtd mGzaTb baZpAe\">\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\"><span class=\" gBYvFf\">Collaborative project with Filipa Godoy Vitorino, PhD, UPR-MSC. In this project we integrate next-generation sequencing data with ecology, physiology, metagenomics, metabolomics and bioinformatics to evaluate the metabolic capacity, and activity of the human microbiome among Puerto Rican women diagnosed with human papillomavirus (HPV) infections and to predict the occurrence of metabolic abnormalities that could lead to cervical cancer development (PMC7235793; PMC7022855; PMC6310238). The long-term goal of this project is to predict the microbiome activity and dynamics for development of new pharmaceutic strategies directed on modification the microbiome and its metabolic phenotype in health and disease.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"h.2464114a461351d6_0\" class=\"yaqOZd\"><\/section>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;1068&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-723669d25101e23f3\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-723669d25101e23f3 uvc-9739  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-723669d25101e23f3 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">DISCOVERY OF THE BIOLOGICAL FUNCTIONS OF MECHANOSENSOR MTL1P OF SACCHAROMYCES CEREVISIAE THROUGH COMPREHENSIVE OMICS ANALYSIS<\/h3><\/div><\/div>[vc_column_text]<\/p>\n<section id=\"h.3e1d518780a900_38\" class=\"yaqOZd\">\n<div class=\"mYVXT\">\n<div class=\"LS81yb VICjCf\" tabindex=\"-1\">\n<div class=\"hJDwNd-AhqUyc-qWD73c purZT-AhqUyc-II5mzb pSzOP-AhqUyc-qWD73c JNdkSc\">\n<div class=\"JNdkSc-SmKAyb\">\n<div class=\"\">\n<div class=\"oKdM2c Kzv0Me\">\n<div id=\"h.3e1d518780a900_46\" class=\"hJDwNd-AhqUyc-qWD73c jXK9ad D2fZ2 OjCsFc wHaque GNzUNc\">\n<div class=\"jXK9ad-SmKAyb\">\n<div class=\"tyJCtd mGzaTb baZpAe\">\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\"><span class=\" gBYvFf\"> Collaborative project with Jose Rodriguez Medina, PhD, UPR-MSC. We identify a novel role for mechanosensor Mtl1p of<\/span><span class=\" gBYvFf\"><em> Saccharomyces cerevisiae<\/em><\/span><span class=\" gBYvFf\"> in complex cellular regulatory mechanisms required to maintain cellular homeostasis using integrative multi-omics analysis of the cellular transcriptome, proteome, metabolome and functional enrichment analyses (PMC8016984).<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"h.2464114a461351d6_0\" class=\"yaqOZd\"><\/section>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner]\n\t\t\t            <\/div>\n        \t<\/dd><dt class=\"\">\n        \t<a class=\"ult-tabto-actitle withBorder ult_a\" id=\"1570556815923-4-4\" style=\"color:#74777b;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1570556815923-4-4\">\n        \t\t<i class=\"accordion-icon\"><\/i>\n        \t\t\t<span class=\"ult_tab_main ult_ac_mainBoth\">\n\t\t\t\t\t   <span  data-ultimate-target='#advanced-tabs-wrap-9375 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text ult_acordian-text ult-responsive\" style=\";color:inherit \" >CHORNA LAB<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t   <div class=\"aio-icon none \" style=\"color:#74777b;font-size:15px;\" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\">\n\t\t\t\t\t   <i class=\"    ult_tab_icon\"  ><\/i>\n\t\t\t\t\t   <\/div>\n\t\t\t\t\t<\/a><\/dt>\n            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t               [vc_empty_space]<div id=\"ultimate-heading-825969d25101e249d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-825969d25101e249d uvc-3043  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"center\" style=\"text-align:center\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-825969d25101e249d h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">MEET THE TEAM<\/h3><\/div><\/div>[vc_media_grid element_width=&#8221;3&#8243; item=&#8221;mediaGrid_BorderedScaleWithTitle&#8221; grid_id=&#8221;vc_gid:1700152329990-77e4f5e4-0133-10&#8243; include=&#8221;1069,1070,1071,1072,1073,1074,1075&#8243;]\n\t\t\t            <\/div>\n        \t<\/dd>\n    \t<\/dl>\n    <!--<div class=\"extraborder\" style=\"background-color:#4f90d1\"><\/div>-->\n<\/div>\n\n<\/div>[\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-289969d25101e7c5a\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-289969d25101e7c5a uvc-5414  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-289969d25101e7c5a h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">PUBLICATIONS<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-289969d25101e7c5a .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><\/p>\n<ul>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Rodr\u00edguez-Graciani, K. M., X. R. Chapa-Dubocq, E. J. Ayala-Arroyo, I. Chaves-Negr\u00f3n, S. Jang, N. Chorna, T. S. Maskrey, P. Wipf and S. Javadov (2022). &#8220;Effects of Ferroptosis on the Metabolome in Cardiac Cells: The Role of Glutaminolysis.&#8221; Antioxidants <strong>11<\/strong>(2): 278. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.3390%2Fantiox11020278&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0Ts7F0YkeCMm3SZSItt7k1\" target=\"_blank\" rel=\"noopener\"><strong>https:\/\/doi.org\/10.3390\/antiox11020278<\/strong><\/a><\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Mart\u00ednez-Mat\u00edas N, Chorna N, Gonz\u00e1lez-Crespo S, Villanueva L, Montes-Rodr\u00edguez I, Melendez-Aponte LM, Roche-Lima A, Carrasquillo-Carri\u00f3n K, Santiago-Cartagena E, Rymond BC, Babu M, Stagljar I, Rodr\u00edguez-Medina JR. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F33795741%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3_jhQ1cOTDF1TCP6608FNL\" target=\"_blank\" rel=\"noopener\">Toward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis. <\/a>Sci Rep. 2021 Apr 1;11(1):7411. doi: 10.1038\/s41598-021-86671-8. PubMed PMID: 33795741; PubMed Central PMCID: PMC8016984.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna N, Godoy-Vitorino F. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F32276347%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2l67vd852MJazref9y1sa_\" target=\"_blank\" rel=\"noopener\">A Protocol for the Multi-Omic Integration of Cervical Microbiota and Urine Metabolomics to Understand Human Papillomavirus (HPV)-Driven Dysbiosis. <\/a>Biomedicines. 2020 Apr 8;8(4). doi: 10.3390\/biomedicines8040081. PubMed PMID: 32276347; PubMed Central PMCID: PMC7235793.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Sanabria-R\u00edos DJ, Morales-Guzm\u00e1n C, Mooney J, Medina S, Pereles-De-Le\u00f3n T, Rivera-Rom\u00e1n A, Ocasio-Malav\u00e9 C, D\u00edaz D, Chorna N, Carballeira NM.<a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F31975430%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2D989yoOf27J0ZNkFk1KjT\" target=\"_blank\" rel=\"noopener\">Antibacterial Activity of Hexadecynoic Acid Isomers toward Clinical Isolates of Multidrug-Resistant Staphylococcus aureus. <\/a>Lipids. 2020 Mar;55(2):101-116. doi: 10.1002\/lipd.12213. Epub 2020 Jan 24. PubMed PMID: 31975430; PubMed Central PMCID: PMC7436198.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna N, Romaguera J, Godoy-Vitorino F. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F31952112%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3DuAc0f6eGqPogr7ZXH8hV\" target=\"_blank\" rel=\"noopener\">Cervicovaginal Microbiome and Urine Metabolome Paired Analysis Reveals Niche Partitioning of the Microbiota in Patients with Human Papilloma Virus Infections. <\/a>Metabolites. 2020 Jan 15;10(1). doi: 10.3390\/metabo10010036. PubMed PMID: 31952112; PubMed Central PMCID: PMC7022855.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Rull\u00e1n-Lind C, Ortiz-Rosario M, Garc\u00eda-Gonz\u00e1lez A, Stojanoff V, Chorna NE, Pietri RB, Baerga-Ortiz A. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F31690733%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3y_yVH0S_4v4oOAoKTdQY1\" target=\"_blank\" rel=\"noopener\">Artificial covalent linkage of bacterial acyl carrier proteins for fatty acid production. <\/a>Sci Rep. 2019 Nov 5;9(1):16011. doi: 10.1038\/s41598-019-52344-w. PubMed PMID: 31690733; PubMed Central PMCID: PMC6831569.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna NE, Chornyy AP. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F30707433%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2JRFut_SPJAV1O3GCPJQYW\" target=\"_blank\" rel=\"noopener\">Metabolomics Analysis of Glutamate Receptor Function. <\/a>Methods Mol Biol. 2019;1941:155-165. doi: 10.1007\/978-1-4939-9077-1_11. PubMed PMID: 30707433; PubMed Central PMCID: PMC6413523.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Godoy-Vitorino F, Ortiz-Morales G, Romaguera J, Sanchez MM, Martinez-Ferrer M, Chorna N. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F30592768%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw1wHbPOOOHr5VScitzbpRZr\" target=\"_blank\" rel=\"noopener\">Discriminating high-risk cervical Human Papilloma Virus infections with urinary biomarkers via non-targeted GC-MS-based metabolomics. <\/a>PLoS One. 2018;13(12):e0209936. doi: 10.1371\/journal.pone.0209936. eCollection 2018. PubMed PMID: 30592768; PubMed Central PMCID: PMC6310238.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Valent\u00edn-Guillama G, L\u00f3pez S, Kucheryavykh YV, Chorna NE, P\u00e9rez J, Ortiz-Rivera J, Inyushin M, Makarov V, Valent\u00edn-Acevedo A, Quinones-Hinojosa A, Boukli N, Kucheryavykh LY. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F30200472%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2geXwZJoLF2btzRRm35OJu\" target=\"_blank\" rel=\"noopener\">HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell. <\/a>Cancers (Basel). 2018 Sep 1;10(9). doi: 10.3390\/cancers10090301. PubMed PMID: 30200472; PubMed Central PMCID: PMC6162763.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chornyy S, Parkhomenko Y, Chorna N. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F28878400%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw1Bu_ihxtYrJY09cTvXs58W\" target=\"_blank\" rel=\"noopener\">Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells. <\/a>Sci Rep. 2017 Sep 6;7(1):10632. doi: 10.1038\/s41598-017-10878-x. PubMed PMID: 28878400; PubMed Central PMCID: PMC5587765.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Santos-Soto IJ, Chorna N, Carballeira NM, V\u00e9lez-Bartolomei JG, M\u00e9ndez-Merced AT, Chornyy AP, Pe\u00f1a de Ortiz S. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F24349072%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw30ezdAqUIuyy-XSA9Tmy_X\" target=\"_blank\" rel=\"noopener\">Voluntary running in young adult mice reduces anxiety-like behavior and increases the accumulation of bioactive lipids in the cerebral cortex. <\/a>PLoS One. 2013;8(12):e81459. doi: 10.1371\/journal.pone.0081459. eCollection 2013. PubMed PMID: 24349072; PubMed Central PMCID: PMC3859495.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna NE, Santos-Soto IJ, Carballeira NM, Morales JL, de la Nuez J, C\u00e1tala-Valentin A, Chornyy AP, V\u00e1zquez-Montes A, De Ortiz SP. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F24223732%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3PPUukGFoKdugSTJ6QTyJl\" target=\"_blank\" rel=\"noopener\">Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation. <\/a>PLoS One. 2013;8(11):e77845. doi: 10.1371\/journal.pone.0077845. eCollection 2013. PubMed PMID: 24223732; PubMed Central PMCID: PMC3818398.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Mikhalovska L, Chorna N, Lazarenko O, Haworth P, Sudre A, Mikhalovsky S. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F21210514%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw1YlZFUf5AJQDve8uqBdvqZ\" target=\"_blank\" rel=\"noopener\">Inorganic coatings for cardiovascular stents: In vitro and in vivo studies. <\/a>J Biomed Mater Res B Appl Biomater. 2011 Feb;96(2):333-41. doi: 10.1002\/jbm.b.31772. Epub 2010 Dec 17. PubMed PMID: 21210514.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Orellano EA, Rivera OJ, Chevres M, Chorna NE, Gonz\u00e1lez FA. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F19882109%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2j7NDzEFQAGwQiV9asVLd2\" target=\"_blank\" rel=\"noopener\">Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression. <\/a>Mol Cell Biochem. 2010 Apr;337(1-2):83-99. doi: 10.1007\/s11010-009-0288-x. Epub 2009 Nov 1. PubMed PMID: 19882109; PubMed Central PMCID: PMC4028074.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Saavedra-Rodr\u00edguez L, V\u00e1zquez A, Ortiz-Zuazaga HG, Chorna NE, Gonz\u00e1lez FA, Andr\u00e9s L, Rodr\u00edguez K, Ram\u00edrez F, Rodr\u00edguez A, Pe\u00f1a de Ortiz S.<a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F19420241%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw308JwYtQC1_ynn-gdhyGO6\" target=\"_blank\" rel=\"noopener\">Identification of flap structure-specific endonuclease 1 as a factor involved in long-term memory formation of aversive learning. <\/a>J Neurosci. 2009 May 6;29(18):5726-37. doi: 10.1523\/JNEUROSCI.4033-08.2009. PubMed PMID: 19420241; PubMed Central PMCID: PMC2699464.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna N, Petrova YI, Kalashnik OM, Platonova TM, Cederholm-Williams S, Skok MV. Receptors for fibrin fragments on neuroendocrine PC-12 cells.Biopolymers and Cell. 2008; 24(4):294-299. doi: 10.7124\/bc.0007AC.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chornyy S, Parkhomenko J, Chorna N. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F17502925%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw17GgSIR-3KC3dl1Fu9pSem\" target=\"_blank\" rel=\"noopener\">Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells. <\/a>Acta Biochim Pol. 2007;54(2):315-22. Epub 2007 May 15. PubMed PMID: 17502925.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna NE, Chevres M, Santos-Berrios C, Orellano EA, Erb L, Gonz\u00e1lez FA. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F17186500%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2rgIr9v9pb5t45BnPhgyUN\" target=\"_blank\" rel=\"noopener\">P2Y2 receptors induced cell surface redistribution of alpha(v) integrin is required for activation of ERK 1\/2 in U937 cells. <\/a>J Cell Physiol. 2007 May;211(2):410-22. doi: 10.1002\/jcp.20946. PubMed PMID: 17186500.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Bagchi S, Liao Z, Gonzalez FA, Chorna NE, Seye CI, Weisman GA, Erb L. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F16186116%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0sW3VRHDrnTiAqTqJw_DTX\" target=\"_blank\" rel=\"noopener\">The P2Y2 nucleotide receptor interacts with alphav integrins to activate Go and induce cell migration. <\/a>J Biol Chem. 2005 Nov 25;280(47):39050-7. doi: 10.1074\/jbc.M504819200. Epub 2005 Sep 26. PubMed PMID: 16186116.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Weisman GA, Wang M, Kong Q, Chorna NE, Neary JT, Sun GY, Gonz\u00e1lez FA, Seye CI, Erb L. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F15953819%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw10gnaGawNSFyr2KR0vSF9A\" target=\"_blank\" rel=\"noopener\">Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytes. <\/a>Mol Neurobiol. 2005;31(1-3):169-83. doi: 10.1385\/MN:31:1-3:169. Review. PubMed PMID: 15953819.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Gonz\u00e1lez FA, Weisman GA, Erb L, Seye CI, Sun GY, Vel\u00e1zquez B, Hern\u00e1ndez-P\u00e9rez M, Chorna NE. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F15953812%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3TrEf296ZbvhzkGLqNZTow\" target=\"_blank\" rel=\"noopener\">Mechanisms for inhibition of P2 receptors signaling in neural cells. <\/a>Mol Neurobiol. 2005;31(1-3):65-79. doi: 10.1385\/MN:31:1-3:065. Review. PubMed PMID: 15953812.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Chorna NE, Santiago-P\u00e9rez LI, Erb L, Seye CI, Neary JT, Sun GY, Weisman GA, Gonz\u00e1lez FA. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F15379893%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2LTdyn59D0ivIIRLH3f9OM\" target=\"_blank\" rel=\"noopener\">P2Y receptors activate neuroprotective mechanisms in astrocytic cells. <\/a>J Neurochem. 2004 Oct;91(1):119-32. doi: 10.1111\/j.1471-4159.2004.02699.x. PubMed PMID: 15379893.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Weisman GA, Griffin K, Santiago\u2010P\u00e9rez LI, Liu J, Krugh B, Flores RV, Chorna NE, Santos\u2010Berr\u00edos C, Vivas\u2010Mej\u00eda PE, Garrad RC, Gonz\u00e1lez FA, Erb L. P2Y2 receptors regulate multiple signal transduction pathways in monocytic cells. Drug development research. 2001 August; 53(2-3):186-192. doi: 10.1002\/ddr.1187.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Santiago-P\u00e9rez LI, Flores RV, Santos-Berr\u00edos C, Chorna NE, Krugh B, Garrad RC, Erb L, Weisman GA, Gonz\u00e1lez FA. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F11267999%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0dVNJ60KbRgSFWBd1938Aq\" target=\"_blank\" rel=\"noopener\">P2Y(2) nucleotide receptor signaling in human monocytic cells: activation, desensitization and coupling to mitogen-activated protein kinases. <\/a>J Cell Physiol. 2001 May;187(2):196-208. doi: 10.1002\/jcp.1063. PubMed PMID: 11267999.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Bobrovnik SA, Nikolaenko IV, Chorna NE. Influence of different factors on transformation of serum immunoglobulins into polyreactive immunoglobulins and their interaction with antigens. Biopolymers and Cell. 1999; 15(3):220. doi: 10.7124\/bc.00051C.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Bobrovnik SA, Lavrenchuk GI, Benkovska NP, Chorna NE. Influence of polyreactive antibodies on proliferation of tumor cells. Experimental Oncology. 1998 September; 20(3-4):202.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Kolodyazhny OI, Gensitski IP, Grishkun EV, Chorna NE. The influence of insect juvenile hormone analogues on the development of the American white butterfly Hyphantria cunea. Reports of the Academy of Sciences of the Ukrainian SSR. Series B, Geological, Chemical and Biological Sciences. 1990 December; 12:49-52.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Gvozdiak OP, Chernaia (Chorna) NE. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F2115965%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0prPBQ1UKJWcUmG4910kD7\" target=\"_blank\" rel=\"noopener\">Polyamines in representative taxa of coryneform and other bacteria. <\/a>Mikrobiol Zh. 1990 Mar-Apr;52(2):29-34. PubMed PMID: 2115965.<\/p>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">\n<\/li>\n<li>\n<p class=\"CDt4Ke zfr3Q\" dir=\"ltr\">Pan&#8217;kova (Chorna) NE, Zherebilo OE, Gvozdiak RI, Stepaniuk VV. <a class=\"XqQF9c rXJpyf\" href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F6336577%2F&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0FJAXKUFAcc5X12KZcCcUx\" target=\"_blank\" rel=\"noopener\">Localization of putrescine in Erwinia carotovora ATCC 15713 cell. <\/a>Mikrobiol Zh. 1983 May-Jun;45(3):8-11. PubMed PMID: 6336577.<\/p>\n<\/li>\n<\/ul>\n<p><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_empty_space][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":1095,"comment_status":"closed","ping_status":"closed","template":"","dt_team_category":[28,26],"class_list":["post-1033","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-assistant-professorsa","dt_team_category-faculty","dt_team_category-28","dt_team_category-26","description-off"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/dt_team\/1033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/types\/dt_team"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/comments?post=1033"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/media\/1095"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/media?parent=1033"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/biochemistry\/wp-json\/wp\/v2\/dt_team_category?post=1033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}