Educational Background

  • S. Chemistry. University of Puerto Rico, Río Piedras Campus, PR, 1988.
  • D. Chemistry. University of Puerto Rico, Río Piedras Campus, PR, 1999.
  • Postdoctoral Fellowship. HIV Pathogenesis. Thomas Jefferson University, Philadelphia, PA, 2002.
  • Postdoctoral Fellowship. Immune Therapy. University of Pennsylvania, Philadelphia, PA, 2004.

Academic Position: Tenured Associate Professor.

Academic Address, Telephone, & Email:

University of Puerto Rico
School of Medicine
Department of Microbiology
P.O. Box 365067
San Juan, P.R. 00936-5067

Phone: (787) 758-2525 X-2098

e-mail:miguel.otero2@upr.edu

Field of Interest:

Development of DNA-Based Vaccines:

Our laboratory is engaged in the development of Immune Therapies designed to protect against Infectious Agents, with an emphasis on DNA-based Vaccines. We work in the modulation of innate responses, focused in the impact of Pattern-Recognition Receptors (PRR) in the adaptive immunity against viral infections. We bring this expertise to our projects having worked on development of pre-clinical Vaccines against Bioterror Agents, as well as having established an active research program focused on DNA-based Vaccines at the University of Puerto Rico School of Medicine. Moreover, we have already successfully developed Vaccine candidates against Smallpox, besides collaborating on Vaccine projects against HIV-1. All these efforts have been documented by our publication record. In addition to our expertise in Vaccine Development, we collaborated in the implementation of the Immune Therapy Unit, which supports proposal activities to be performed by the HIV and Substance Abuse Laboratory Core at the Universidad Central del Caribe School of Medicine.

Complete List of Published Work in My Bibliography:

http://www.ncbi.nlm.nih.gov/sites/myncbi/miguel.otero.2/bibliography/48037371/public/?sort=date&direction=ascending.

Research Support

1SC3GM116698-01

Vaccine Development against Infectious Diseases

The goal of this project is to develop a safe vaccine that could be used for all population, including immunosuppressive individuals, in case of a smallpox bioterror attack.

Role: PI.