{"id":2245,"date":"2024-05-28T15:01:58","date_gmt":"2024-05-28T19:01:58","guid":{"rendered":"https:\/\/md.rcm.upr.edu\/micro\/?post_type=dt_team&#038;p=2245"},"modified":"2024-07-08T18:37:23","modified_gmt":"2024-07-08T22:37:23","slug":"dr-osmarie-martinez","status":"publish","type":"dt_team","link":"https:\/\/md.rcm.upr.edu\/micro\/dt_team\/dr-osmarie-martinez\/","title":{"rendered":"Dr. Osmarie Martinez"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-87126a06012b053fe\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-87126a06012b053fe uvc-3530 accent-subtitle-color\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-87126a06012b053fe h2'  data-responsive-json-new='{\"font-size\":\"desktop:30px;mobile_landscape:34px;\",\"line-height\":\"desktop:40px;mobile_landscape:44px;\"}' ><h2 style=\"font-weight:bold;color:#0a0a0a;margin-bottom:10px;\">Dr. Osmarie Martinez<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-87126a06012b053fe .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"desktop:18px;mobile_landscape:20px;\",\"line-height\":\"desktop:34px;mobile_landscape:30px;\"}'  style=\"font-weight:bold;margin-bottom:30px;\">Assistant Professor<\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;]<div class=\"ult-content-box-container \" >\t\t<div class=\"ult-content-box\" style=\"background-color:#545454;box-shadow: px px px px none;border-style:solid;border-width:5px;border-radius:5px;border-color:#545454;padding:10px;-webkit-transition: all 700ms ease;-moz-transition: all 700ms ease;-ms-transition: all 700ms ease;-o-transition: all 700ms ease;transition: all 700ms ease;\"  data-hover_box_shadow=\"none\"     data-bg=\"#545454\"  data-border_color=\"#545454\" ><style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-54cecc2461279da74212b3e97b64ff32.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-54cecc2461279da74212b3e97b64ff32.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-54cecc2461279da74212b3e97b64ff32 .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-54cecc2461279da74212b3e97b64ff32 .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-54cecc2461279da74212b3e97b64ff32 alignnone  enable-bg-rollover dt-icon-bg-off\" style=\"margin-top:0px; margin-bottom:0px; margin-left:0px; margin-right:0px; width:300px;\"><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20300%20300&#39;%2F%3E\" data-src=\"https:\/\/md.rcm.upr.edu\/micro\/wp-content\/uploads\/sites\/22\/2024\/05\/osmarie-martinez-scaled-300x300.jpg\" data-srcset=\"https:\/\/md.rcm.upr.edu\/micro\/wp-content\/uploads\/sites\/22\/2024\/05\/osmarie-martinez-scaled-300x300.jpg 300w, https:\/\/md.rcm.upr.edu\/micro\/wp-content\/uploads\/sites\/22\/2024\/05\/osmarie-martinez-scaled-600x600.jpg 600w\" loading=\"eager\" sizes=\"(max-width: 300px) 100vw, 300px\" width=\"300\" height=\"300\"  data-dt-location=\"https:\/\/md.rcm.upr.edu\/micro\/dt_team\/dr-osmarie-martinez\/osmarie-martinez\/\" style=\"--ratio: 300 \/ 300;\" alt=\"Dr. Osmarie Martinez\" \/><\/div><\/div><\/div>[vc_empty_space][vc_column_text]<span style=\"color: #ffffff;\"><strong>Contact Info<\/strong><\/span>[\/vc_column_text]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-1891\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-mail-03\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-1891 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"mailto:osmarie.martinez@upr.edu\">osmarie.martinez@upr.edu<\/a><\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-7326\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-05\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-7326 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Department of Microbiology and Medical Zoology,<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto-Rico-School of Medicine<\/span><br \/>\n<span style=\"color: #ffffff;\">Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">P.O. Box 365067,<\/span><br \/>\n<span style=\"color: #ffffff;\">San Juan, P.R. 00936-5067<\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-4950\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-phone-071\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-4950 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Telephone: (787) 758-2525 ext. 1354<\/span><\/span><\/div><\/li><\/ul><\/div>[vc_column_text]<span style=\"color: #ffffff;\"><strong>Education<\/strong><\/span>[\/vc_column_text]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><span style=\"color: #ffffff;\">B.S. General Biology, June 2009<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico at Humacao, Humacao, PR<\/span><\/li>\n<li><span style=\"color: #ffffff;\">Ph.D. in Microbiology and Medical Zoology June 2017<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico, Medical Sciences Campus<\/span><\/li>\n<li><span style=\"color: #ffffff;\">Post-doc February 2019-February 2024<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico, Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">Department of Anatomy and Neurobiology<\/span><\/li>\n<\/ul>\n<\/div>\t\t<\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-84996a06012b07285\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-84996a06012b07285 uvc-2000  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-84996a06012b07285 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">ACADEMIC PROFILES<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-84996a06012b07285 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><strong>LINKEDIN<\/strong>:\u00a0<a href=\"https:\/\/www.linkedin.com\/in\/osmarie-mart%C3%ADnez-a3a429137\/\">https:\/\/www.linkedin.com\/in\/osmarie-mart%C3%ADnez-a3a429137\/<\/a><br \/>\n<strong>ResearchGate<\/strong>: https:\/\/www.researchgate.net\/profile\/Osmarie-Martinez-2<\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-94726a06012b072d7\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-94726a06012b072d7 uvc-6166  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-94726a06012b072d7 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">RESEARCH INTEREST<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-94726a06012b072d7 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Antibiotics are indispensable in treating infectious diseases, often administered orally. However, their use can disrupt the delicate balance of gut microbes, affecting the Gut-Brain axis, a bidirectional communication system between the gut microbiota and the nervous system. Such disruptions may lead to neuroinflammation and neurodegeneration. While studies have explored the effects of antibiotics on fear-related behaviors in rodents, the impact on avoidance behaviors, ultrasonic vocalizations (USV) and specific brain regions remains largely unexplored. Our research aims to fill this gap by investigating how oral antibiotic exposure affects avoidance behaviors, USV and brain activity in rodents. By standardizing the acquisition and analysis of USVs and evaluating the effects of antibiotics on avoidance behaviors, we hope to uncover insights into the role of antibiotics in communication and emotional processing. This understanding will help in the targeted interventions addressing anxiety disorders through modulation of the gut-brain axis.<\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-42556a06012b0731b\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-42556a06012b0731b uvc-2266  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-42556a06012b0731b h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">PUBLICATIONS<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-42556a06012b0731b .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><\/p>\n<ul>\n<li>O. Mart\u00ednez, A. Bravo, N.J. Pinto. (2009). Electospun Nanofibers of Poly(vinylidene fluoride-trifluoroethylene)-Poly(4,4-ethylenedioxythiophene)Poly(styrene sulfonate) Composite, Macromolecules.<\/li>\n<li>Mart\u00ednez O, Miranda E, Ram\u00edrez M, Santos S, Rivera C, V\u00e1zquez L, et al. (2015) Immunomodulator-Based Enhancement of Anti Smallpox Immune Responses. PLoS ONE.<\/li>\n<li>Osmarie Mart\u00ednez, Ariana Bravo, Saritza Santos, Maite Ram\u00edrez, Eric Miranda, Joanna Shisler, and Miguel Otero. (2017) Vaccination with\u00a0a codon-optimized A27L-containing plasmid decreases virus replication and dissemination after vaccinia virus challenge. Vaccine.<\/li>\n<li>Ram\u00edrez M, Santos S, Mart\u00ednez O, Rodr\u00edguez R, Miranda E, Ramos-Perez WD, Otero M. (2018) Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA. Vaccine.<\/li>\n<li>Santos S, Ram\u00edrez M, Miranda E, Reyes N, Mart\u00ednez O, Acosta-Santiago M, Rivera JM, Otero M (2019). Enhancement of Immune Responses by Guanosine-Based Particles in DNA Plasmid Formulations against Infectious Diseases. J Immunol Res.<\/li>\n<\/ul>\n<p><\/div><\/div>[vc_empty_space]<div id=\"ultimate-heading-24176a06012b07358\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-24176a06012b07358 uvc-2565  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-24176a06012b07358 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">Book Chapters<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-24176a06012b07358 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><\/p>\n<ul>\n<li>Anti-protozoan drugs. A. Muro, A.E. Serrano,and J.L. P\u00e9rez de Arellano. Chapter 22, pp. 331-343.<\/li>\n<li>Anti-helminthic drugs. A. Muro, A.E. Serrano,and J.L. P\u00e9rez de Arellano. Chapter 23, pp. 345-353.<\/li>\n<\/ul>\n<p><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_empty_space][vc_empty_space][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":2246,"comment_status":"closed","ping_status":"closed","template":"","dt_team_category":[26],"class_list":["post-2245","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-faculty","dt_team_category-26","description-off"],"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/dt_team\/2245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/types\/dt_team"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/comments?post=2245"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/media\/2246"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/media?parent=2245"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/micro\/wp-json\/wp\/v2\/dt_team_category?post=2245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}