{"id":1159,"date":"2021-10-07T09:15:31","date_gmt":"2021-10-07T13:15:31","guid":{"rendered":"https:\/\/md.rcm.upr.edu\/pharmacology\/?post_type=dt_team&#038;p=1159"},"modified":"2023-09-08T11:50:55","modified_gmt":"2023-09-08T15:50:55","slug":"dr-ingrid-bonilla","status":"publish","type":"dt_team","link":"https:\/\/md.rcm.upr.edu\/pharmacology\/dt_team\/dr-ingrid-bonilla\/","title":{"rendered":"Dr. Ingrid Bonilla"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-904469d29500573ef\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-904469d29500573ef uvc-585 accent-subtitle-color\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-904469d29500573ef h2'  data-responsive-json-new='{\"font-size\":\"desktop:30px;mobile_landscape:34px;\",\"line-height\":\"desktop:40px;mobile_landscape:44px;\"}' ><h2 style=\"font-weight:bold;color:#0a0a0a;margin-bottom:10px;\">Dr. Ingrid Bonilla<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-904469d29500573ef .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"desktop:18px;mobile_landscape:20px;\",\"line-height\":\"desktop:34px;mobile_landscape:30px;\"}'  style=\"font-weight:bold;margin-bottom:30px;\">Assistant Professor Ad-honorem<\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;]<div class=\"ult-content-box-container \" >\t\t<div class=\"ult-content-box\" style=\"background-color:#545454;box-shadow: px px px px none;border-style:solid;border-width:5px;border-radius:5px;border-color:#545454;padding:10px;-webkit-transition: all 700ms ease;-moz-transition: all 700ms ease;-ms-transition: all 700ms ease;-o-transition: all 700ms ease;transition: all 700ms ease;\"  data-hover_box_shadow=\"none\"     data-bg=\"#545454\"  data-border_color=\"#545454\" ><style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-9425cfa9f2d416d237fad5e1963a6b73.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-9425cfa9f2d416d237fad5e1963a6b73.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-9425cfa9f2d416d237fad5e1963a6b73 .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-9425cfa9f2d416d237fad5e1963a6b73 .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-9425cfa9f2d416d237fad5e1963a6b73 alignnone  enable-bg-rollover dt-icon-bg-off\" style=\"margin-top:0px; margin-bottom:0px; margin-left:0px; margin-right:0px; width:300px;\"><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20300%20300&#39;%2F%3E\" data-src=\"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-content\/uploads\/sites\/21\/2021\/10\/drabonilla.jpg\" data-srcset=\"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-content\/uploads\/sites\/21\/2021\/10\/drabonilla.jpg 300w\" loading=\"eager\" sizes=\"(max-width: 300px) 100vw, 300px\" width=\"300\" height=\"300\"  data-dt-location=\"https:\/\/md.rcm.upr.edu\/pharmacology\/dt_team\/dr-ingrid-bonilla\/drabonilla\/\" style=\"--ratio: 300 \/ 300;\" alt=\"Dra. Bonilla\" \/><\/div><\/div><\/div>[vc_empty_space][vc_column_text]<span style=\"color: #ffffff;\"><strong>Contact Info<\/strong><\/span>[\/vc_column_text]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-8822\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-mail-03\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-8822 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"mailto:ingrid.bonilla4@upr.edu\">ingrid.bonilla4@upr.edu<\/a><\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-3471\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-05\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-3471 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Room A-340<\/span><br \/>\n<span style=\"color: #ffffff;\">Guillermo Arbona Irizarry Building<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">San Juan, PR 00936<\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-8669\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-phone-071\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-8669 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">787-758-2525 Ext. 1306<\/span><\/span><\/div><\/li><\/ul><\/div>[vc_column_text]<span style=\"color: #ffffff;\"><strong>Education<\/strong><\/span>[\/vc_column_text]<div class=\"standard-arrow list-divider bullet-top\"><\/div>\t\t<\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-383569d295005cb92\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-383569d295005cb92 uvc-3912  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-383569d295005cb92 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">PUBLICATIONS<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-383569d295005cb92 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Bonilla IM, Baine S, Pokrass A, Mari\u00e1ngelo JIE, Kalyanasundaram A, Bogdanov V, Mezache L, Sakuta G, Beard CM, Belevych A, Tikunova S, Terentyeva R, Terentyev D, Davis J, Veeraraghavan R, Carnes CA, Gy\u00f6rke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36995910\/\">STIM1 ablation impairs exercise-induced physiological cardiac hypertrophy and dysregulates autophagy in mouse hearts.\u00a0<\/a>J Appl Physiol (1985).\u00a02023 May 1;134(5):1287-1299.\u00a0doi: 10.1152\/japplphysiol.00363.2022.\u00a0Epub 2023 Mar 30.\u00a0PubMed PMID: 36995910; PubMed Central PMCID: PMC10190841.<\/p>\n<p>Vicenty-Rivera S, Bonilla Mercado I.\u00a0Cardiac Amyloidosis.\u00a0In:\u00a0Said DM, editor.\u00a0New Insights on Cardiomyopathy\u00a0intechopen.com: IntechOpen;\u00a02023.<\/p>\n<p>Uddin ME, Eisenmann ED, Li Y, Huang KM, Garrison DA, Talebi Z, Gibson AA, Jin Y, Nepal M, Bonilla IM, Fu Q, Sun X, Millar A, Tarasov M, Jay CE, Cui X, Einolf HJ, Pelis RM, Smith SA, Radwa\u0144ski PB, Sweet DH, K\u00f6nig J, Fromm MF, Carnes CA, Hu S, Sparreboom A.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35955741\/\">MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.\u00a0<\/a>Int J Mol Sci.\u00a02022 Aug 3;23(15).\u00a0doi: 10.3390\/ijms23158607.\u00a0PubMed PMID: 35955741; PubMed Central PMCID: PMC9369325.<\/p>\n<p>Baine S, Bonilla I, Belevych A, Stepanov A, Dorn LE, Terentyeva R, Terentyev D, Accornero F, Carnes CA, Gyorke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33755308\/\">Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1-mediated calcium entry in heart failure.\u00a0<\/a>J Cell Mol Med.\u00a02021 May;25(10):4637-4648.\u00a0doi: 10.1111\/jcmm.16356.\u00a0Epub 2021 Mar 23.\u00a0PubMed PMID: 33755308; PubMed Central PMCID: PMC8107086.<\/p>\n<p>Huang KM, Zavorka Thomas M, Magdy T, Eisenmann ED, Uddin ME, DiGiacomo DF, Pan A, Keiser M, Otter M, Xia SH, Li Y, Jin Y, Fu Q, Gibson AA, Bonilla IM, Carnes CA, Corps KN, Coppola V, Smith SA, Addison D, Nies AT, Bundschuh R, Chen T, Lustberg MB, Wang J, Oswald S, Campbell MJ, Yan PS, Baker SD, Hu S, Burridge PW, Sparreboom A.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33495337\/\">Targeting OCT3 attenuates doxorubicin-induced cardiac injury.\u00a0<\/a>Proc Natl Acad Sci U S A.\u00a02021 Feb 2;118(5).\u00a0doi: 10.1073\/pnas.2020168118.\u00a0PubMed PMID: 33495337; PubMed Central PMCID: PMC7865186.<\/p>\n<p>Liu B, Tow B, Bonilla I.\u00a0Molecular Mechanism and Current Therapies for Catecholaminergic Polymorphic Ventricular Tachycardia.\u00a0In:\u00a0Zima E, editor.\u00a0Cardiac Arrhythmias\u00a0intechopen.com: IntechOpen;\u00a02021.<\/p>\n<p>Baine S, Thomas J, Bonilla I, Ivanova M, Belevych A, Li J, Veeraraghavan R, Radwanski PB, Carnes C, Gyorke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32580946\/\">Muscarinic-dependent phosphorylation of the cardiac ryanodine receptor by protein kinase G is mediated by PI3K-AKT-nNOS signaling.\u00a0<\/a>J Biol Chem.\u00a02020 Aug 14;295(33):11720-11728.\u00a0doi: 10.1074\/jbc.RA120.014054.\u00a0Epub 2020 Jun 24.\u00a0PubMed PMID: 32580946; PubMed Central PMCID: PMC7450129.<\/p>\n<p>Hamilton S, Terentyeva R, Martin B, Perger F, Li J, Stepanov A, Bonilla IM, Knollmann BC, Radwa\u0144ski PB, Gy\u00f6rke S, Belevych AE, Terentyev D.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32444920\/\">Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS.\u00a0<\/a>Basic Res Cardiol.\u00a02020 May 22;115(4):38.\u00a0doi: 10.1007\/s00395-020-0797-z.\u00a0PubMed PMID: 32444920; PubMed Central PMCID: PMC7244455.<\/p>\n<p>Long VP 3rd, Bonilla IM, Baine S, Glynn P, Kumar S, Schober K, Mowrey K, Weiss R, Lee NY, Mohler PJ, Gy\u00f6rke S, Hund TJ, Fedorov VV, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31751583\/\">Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated I<sub>Kado<\/sub>.\u00a0<\/a>Life Sci.\u00a02020 Jan 1;240:117068.\u00a0doi: 10.1016\/j.lfs.2019.117068.\u00a0Epub 2019 Nov 18.\u00a0PubMed PMID: 31751583; PubMed Central PMCID: PMC7294905.<\/p>\n<p>Bonilla IM, Belevych AE, Baine S, Stepanov A, Mezache L, Bodnar T, Liu B, Volpe P, Priori S, Weisleder N, Sakuta G, Carnes CA, Radwa\u0144ski PB, Veeraraghavan R, Gyorke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31308393\/\">Enhancement of Cardiac Store Operated Calcium Entry (SOCE) within Novel Intercalated Disk Microdomains in Arrhythmic Disease.\u00a0<\/a>Sci Rep.\u00a02019 Jul 15;9(1):10179.\u00a0doi: 10.1038\/s41598-019-46427-x.\u00a0PubMed PMID: 31308393; PubMed Central PMCID: PMC6629850.<\/p>\n<p>Belevych AE, Ho HT, Bonilla IM, Terentyeva R, Schober KE, Terentyev D, Carnes CA, Gy\u00f6rke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28612155\/\">The role of spatial organization of Ca<sup>2+<\/sup>\u00a0release sites in the generation of arrhythmogenic diastolic Ca<sup>2+<\/sup>\u00a0release in myocytes from failing hearts.\u00a0<\/a>Basic Res Cardiol.\u00a02017 Jul;112(4):44.\u00a0doi: 10.1007\/s00395-017-0633-2.\u00a0Epub 2017 Jun 13.\u00a0PubMed PMID: 28612155; PubMed Central PMCID: PMC5796415.<\/p>\n<p>Tanwar V, Gorr MW, Velten M, Eichenseer CM, Long VP 3rd, Bonilla IM, Shettigar V, Ziolo MT, Davis JP, Baine SH, Carnes CA, Wold LE.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28400369\/\">In Utero Particulate Matter Exposure Produces Heart Failure, Electrical Remodeling, and Epigenetic Changes at Adulthood.\u00a0<\/a>J Am Heart Assoc.\u00a02017 Apr 11;6(4).\u00a0doi: 10.1161\/JAHA.117.005796.\u00a0PubMed PMID: 28400369; PubMed Central PMCID: PMC5533043.<\/p>\n<p>Ho HT, Belevych AE, Liu B, Bonilla IM, Radwa\u0144ski PB, Kubasov IV, Valdivia HH, Schober K, Carnes CA, Gy\u00f6rke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27647848\/\">Muscarinic Stimulation Facilitates Sarcoplasmic Reticulum Ca Release by Modulating Ryanodine Receptor 2 Phosphorylation Through Protein Kinase G and Ca\/Calmodulin-Dependent Protein Kinase II.\u00a0<\/a>Hypertension.\u00a02016 Nov;68(5):1171-1178.\u00a0doi: 10.1161\/HYPERTENSIONAHA.116.07666.\u00a0Epub 2016 Sep 19.\u00a0Review.\u00a0PubMed PMID: 27647848; PubMed Central PMCID: PMC5063706.<\/p>\n<p>Bonilla IM, Nishijima Y, Vargas-Pinto P, Baine SH, Sridhar A, Li C, Billman GE, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27378936\/\">Chronic Omega-3 Polyunsaturated Fatty Acid Treatment Variably Affects Cellular Repolarization in a Healed Post-MI Arrhythmia Model.\u00a0<\/a>Front Physiol.\u00a02016;7:225.\u00a0doi: 10.3389\/fphys.2016.00225.\u00a0eCollection 2016.\u00a0PubMed PMID: 27378936; PubMed Central PMCID: PMC4906012.<\/p>\n<p>Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, Spoonamore KG, Zhang C, Weiss R, Binkley PF, Janssen PM, Kilic A, Higgins RS, Sun M, Ma J, Dobrev D, Zhang M, Carnes CA, Vatta M, Rasband MN, Hund TJ, Mohler PJ.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25632041\/\">Dysfunction in the \u03b2II spectrin-dependent cytoskeleton underlies human arrhythmia.\u00a0<\/a>Circulation.\u00a02015 Feb 24;131(8):695-708.\u00a0doi: 10.1161\/CIRCULATIONAHA.114.013708.\u00a0Epub 2015 Jan 28.\u00a0PubMed PMID: 25632041; PubMed Central PMCID: PMC4342332.<\/p>\n<p>Long VP 3rd, Bonilla IM, Vargas-Pinto P, Nishijima Y, Sridhar A, Li C, Mowrey K, Wright P, Velayutham M, Kumar S, Lee NY, Zweier JL, Mohler PJ, Gy\u00f6rke S, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25596015\/\">Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling.\u00a0<\/a>Life Sci.\u00a02015 Feb 15;123:61-71.\u00a0doi: 10.1016\/j.lfs.2014.12.024.\u00a0Epub 2015 Jan 14.\u00a0PubMed PMID: 25596015; PubMed Central PMCID: PMC4763601.<\/p>\n<p>Bonilla IM, Long VP 3rd, Vargas-Pinto P, Wright P, Belevych A, Lou Q, Mowrey K, Yoo J, Binkley PF, Fedorov VV, Gy\u00f6rke S, Janssen PM, Kilic A, Mohler PJ, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25271970\/\">Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure.\u00a0<\/a>PLoS One.\u00a02014;9(10):e108824.\u00a0doi: 10.1371\/journal.pone.0108824.\u00a0eCollection 2014.\u00a0PubMed PMID: 25271970; PubMed Central PMCID: PMC4182742.<\/p>\n<p>Bonilla IM, Vargas-Pinto P, Nishijima Y, Pedraza-Toscano A, Ho HT, Long VP 3rd, Belevych AE, Glynn P, Houmsse M, Rhodes T, Weiss R, Hund TJ, Hamlin RL, Gy\u00f6rke S, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24256556\/\">Ibandronate and ventricular arrhythmia risk.\u00a0<\/a>J Cardiovasc Electrophysiol.\u00a02014 Mar;25(3):299-306.\u00a0doi: 10.1111\/jce.12327.\u00a0Epub 2013 Dec 20.\u00a0PubMed PMID: 24256556; PubMed Central PMCID: PMC4148051.<\/p>\n<p>Belevych AE, Ho HT, Terentyeva R, Bonilla IM, Terentyev D, Carnes CA, Gyorke S, Billman GE.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24205228\/\">Dietary omega-3 fatty acids promote arrhythmogenic remodeling of cellular Ca2+ handling in a postinfarction model of sudden cardiac death.\u00a0<\/a>PLoS One.\u00a02013;8(10):e78414.\u00a0doi: 10.1371\/journal.pone.0078414.\u00a0eCollection 2013.\u00a0PubMed PMID: 24205228; PubMed Central PMCID: PMC3799693.<\/p>\n<p>Bonilla IM, Sridhar A, Nishijima Y, Gy\u00f6rke S, Cardounel AJ, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23364607\/\">Differential effects of the peroxynitrite donor, SIN-1, on atrial and ventricular myocyte electrophysiology.\u00a0<\/a>J Cardiovasc Pharmacol.\u00a02013 May;61(5):401-7.\u00a0doi: 10.1097\/FJC.0b013e31828748ca.\u00a0PubMed PMID: 23364607; PubMed Central PMCID: PMC3648597.<\/p>\n<p>Bonilla IM, Belevych AE, Sridhar A, Nishijima Y, Ho HT, He Q, Kukielka M, Terentyev D, Terentyeva R, Liu B, Long VP, Gy\u00f6rke S, Carnes CA, Billman GE.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23042911\/\">Endurance exercise training normalizes repolarization and calcium-handling abnormalities, preventing ventricular fibrillation in a model of sudden cardiac death.\u00a0<\/a>J Appl Physiol (1985).\u00a02012 Dec 1;113(11):1772-83.\u00a0doi: 10.1152\/japplphysiol.00175.2012.\u00a0Epub 2012 Oct 4.\u00a0PubMed PMID: 23042911; PubMed Central PMCID: PMC3544509.<\/p>\n<p>Wang H, Bonilla IM, Huang X, He Q, Kohr MJ, Carnes CA, Ziolo MT.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22970362\/\">Prolonged Action Potential and After depolarizations Are Not due to Changes in Potassium Currents in NOS3 Knockout Ventricular Myocytes.\u00a0<\/a>J Signal Transduct.\u00a02012;2012:645721.\u00a0doi: 10.1155\/2012\/645721.\u00a0Epub 2012 Aug 28.\u00a0PubMed PMID: 22970362; PubMed Central PMCID: PMC3434404.<\/p>\n<p>Gudmundsson H, Curran J, Kashef F, Snyder JS, Smith SA, Vargas-Pinto P, Bonilla IM, Weiss RM, Anderson ME, Binkley P, Felder RB, Carnes CA, Band H, Hund TJ, Mohler PJ.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22406195\/\">Differential regulation of EHD3 in human and mammalian heart failure.\u00a0<\/a>J Mol Cell Cardiol.\u00a02012 May;52(5):1183-90.\u00a0doi: 10.1016\/j.yjmcc.2012.02.008.\u00a0Epub 2012 Mar 3.\u00a0PubMed PMID: 22406195; PubMed Central PMCID: PMC3360944.<\/p>\n<p>Bonilla IM, Sridhar A, Gy\u00f6rke S, Cardounel AJ, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22536189\/\">Nitric oxide synthases and atrial fibrillation.\u00a0<\/a>Front Physiol.\u00a02012;3:105.\u00a0doi: 10.3389\/fphys.2012.00105.\u00a0eCollection 2012.\u00a0PubMed PMID: 22536189; PubMed Central PMCID: PMC3332924.<\/p>\n<p>Belevych AE, Terentyev D, Terentyeva R, Ho HT, Gyorke I, Bonilla IM, Carnes CA, Billman GE, Gy\u00f6rke S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22223353\/\">Shortened Ca2+ signaling refractoriness underlies cellular arrhythmogenesis in a postinfarction model of sudden cardiac death.\u00a0<\/a>Circ Res.\u00a02012 Feb 17;110(4):569-77.\u00a0doi: 10.1161\/CIRCRESAHA.111.260455.\u00a0Epub 2012 Jan 5.\u00a0PubMed PMID: 22223353; PubMed Central PMCID: PMC4068617.<\/p>\n<p>Nishijima Y, Sridhar A, Bonilla I, Velayutham M, Khan M, Terentyeva R, Li C, Kuppusamy P, Elton TS, Terentyev D, Gy\u00f6rke S, Zweier JL, Cardounel AJ, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21460065\/\">Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology.\u00a0<\/a>Cardiovasc Res.\u00a02011 Jul 1;91(1):71-9.\u00a0doi: 10.1093\/cvr\/cvr087.\u00a0Epub 2011 Apr 1.\u00a0PubMed PMID: 21460065; PubMed Central PMCID: PMC3112023.<\/p>\n<p>Sridhar A, Nishijima Y, Terentyev D, Terentyeva R, Uelmen R, Kukielka M, Bonilla IM, Robertson GA, Gy\u00f6rke S, Billman GE, Carnes CA.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18768760\/\">Repolarization abnormalities and afterdepolarizations in a canine model of sudden cardiac death.\u00a0<\/a>Am J Physiol Regul Integr Comp Physiol.\u00a02008 Nov;295(5):R1463-72.\u00a0doi: 10.1152\/ajpregu.90583.2008.\u00a0Epub 2008 Sep 3.\u00a0PubMed PMID: 18768760; PubMed Central PMCID: PMC2584860.<\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":1172,"comment_status":"closed","ping_status":"closed","template":"","dt_team_category":[34],"class_list":["post-1159","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-faculty","dt_team_category-34","description-off"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team\/1159","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/types\/dt_team"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/comments?post=1159"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/media\/1172"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/media?parent=1159"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team_category?post=1159"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}