{"id":870,"date":"2016-03-07T19:41:14","date_gmt":"2016-03-07T19:41:14","guid":{"rendered":"http:\/\/md.rcm.upr.edu\/pharmacology\/?post_type=dt_team&#038;p=870"},"modified":"2023-09-08T11:53:55","modified_gmt":"2023-09-08T15:53:55","slug":"dr-susan-corey-specht","status":"publish","type":"dt_team","link":"https:\/\/md.rcm.upr.edu\/pharmacology\/dt_team\/dr-susan-corey-specht\/","title":{"rendered":"Dr. Susan Corey"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-225669d4e7012491d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-225669d4e7012491d uvc-4892 accent-subtitle-color\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-225669d4e7012491d h2'  data-responsive-json-new='{\"font-size\":\"desktop:30px;mobile_landscape:34px;\",\"line-height\":\"desktop:40px;mobile_landscape:44px;\"}' ><h2 style=\"font-weight:bold;color:#0a0a0a;margin-bottom:10px;\">Dr. Susan Corey<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-225669d4e7012491d .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"desktop:18px;mobile_landscape:20px;\",\"line-height\":\"desktop:34px;mobile_landscape:30px;\"}'  style=\"font-weight:bold;margin-bottom:30px;\">Professor Ad-Honorem<\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content&#8221; bg_type=&#8221;bg_color&#8221;][vc_column width=&#8221;1\/4&#8243;]<div class=\"ult-content-box-container \" >\t\t<div class=\"ult-content-box\" style=\"background-color:#545454;box-shadow: px px px px none;border-style:solid;border-width:5px;border-radius:5px;border-color:#545454;padding:10px;-webkit-transition: all 700ms ease;-moz-transition: all 700ms ease;-ms-transition: all 700ms ease;-o-transition: all 700ms ease;transition: all 700ms ease;\"  data-hover_box_shadow=\"none\"     data-bg=\"#545454\"  data-border_color=\"#545454\" ><style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-dde1f6f57327b4f7d21af59da3a0c0df.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-dde1f6f57327b4f7d21af59da3a0c0df.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-dde1f6f57327b4f7d21af59da3a0c0df .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-dde1f6f57327b4f7d21af59da3a0c0df .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-dde1f6f57327b4f7d21af59da3a0c0df alignnone  enable-bg-rollover dt-icon-bg-off\" style=\"margin-top:0px; margin-bottom:0px; margin-left:0px; margin-right:0px; width:300px;\"><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20300%20300&#39;%2F%3E\" data-src=\"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-content\/uploads\/sites\/21\/2016\/03\/susan-corey.jpg\" data-srcset=\"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-content\/uploads\/sites\/21\/2016\/03\/susan-corey.jpg 300w\" loading=\"eager\" sizes=\"(max-width: 300px) 100vw, 300px\" width=\"300\" height=\"300\"  data-dt-location=\"https:\/\/md.rcm.upr.edu\/pharmacology\/dt_team\/dr-susan-corey-specht\/susan-corey\/\" style=\"--ratio: 300 \/ 300;\" alt=\"Dra. Susan Corey\" \/><\/div><\/div><\/div>[vc_empty_space][vc_column_text]<span style=\"color: #ffffff;\"><strong>Contact Info<\/strong><\/span>[\/vc_column_text]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-3703\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-mail-03\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-3703 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"mailto:susan.corey@upr.edu\">susan.corey@upr.edu<\/a><\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-9033\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-05\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-9033 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">Room A338<\/span><br \/>\n<span style=\"color: #ffffff;\">Guillermo Arbona Irizarry Building<\/span><br \/>\n<span style=\"color: #ffffff;\">University of Puerto Rico Medical Sciences Campus<\/span><br \/>\n<span style=\"color: #ffffff;\">San Juan, PR 00936<\/span><\/span><\/div><\/li><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-2629\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:5px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon none \"  style=\"color:#ffffff;font-size:32px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-phone-071\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-2629 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><span style=\"color: #ffffff;\">787-758-2525 Ext. 1358<\/span><\/span><\/div><\/li><\/ul><\/div>[vc_column_text]<span style=\"color: #ffffff;\"><strong>Education<\/strong><\/span>[\/vc_column_text]<div class=\"standard-arrow list-divider bullet-top\"><p><span style=\"color: #ffffff;\">\u2022 BS, (Zoology), Syracuse University, Syracuse, New York<\/span><br \/>\n<span style=\"color: #ffffff;\">\u2022 Ph.D. (Pharmacology), Dr. Joseph D. Robinson\u2019s laboratory, State University of New York, Upstate Medical Center, Syracuse, New York<\/span><br \/>\n<span style=\"color: #ffffff;\">\u2022 Postdoctoral: Axonal transport, Dr. Bernice Grafstein\u2019s laboratory, Department of Physiology, Cornell University College of Medicine, New York, NY<\/span><br \/>\n<span style=\"color: #ffffff;\">\u2022 Visiting Professor, 2-D gel electrophoresis, Dr. Philip Siekevitz\u2019s laboratory, The Rockefeller University, New York, NY, <\/span><br \/>\n<span style=\"color: #ffffff;\">\u2022 Visiting Professor, 2-D gel electrophoresis, Dr. Gianni Piperno\u2019s laboratory, The Rockefeller University, New York, NY.<\/span><br \/>\n<span style=\"color: #ffffff;\">\u2022 Visiting Professor, Na,K-ATPase isoforms, Dr. Kathleen Sweadner, Massachusetts General Hospital, Harvard Medical School, Boston, MA. <\/span><\/p>\n<\/div>\t\t<\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-684469d4e70125727\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-684469d4e70125727 uvc-1269  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-684469d4e70125727 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h3 style=\"font-weight:bold;margin-bottom:30px;\">PUBLICATIONS<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-684469d4e70125727 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><\/p>\n<ul>\n<li><strong>Specht SC, <\/strong>Robinson JD. Stimulation of the (Na,K)\u2011dependent ATPase by amino acids and phosphatidyl serine: chelation of trace metal inhibitors. Arch. Biochem. Biophys. 1973;154:314\u2011323.<\/li>\n<li><strong>Specht SC, G<\/strong>rafstein B. Accumulation of radioactive protein in mouse cerebral cortex after injection of 3H\u2011fucose into the eye. Exp. Neurol. 1973;41:705\u2011722.<\/li>\n<li>Grafstein B, Miller JA, Ledeen RW, Haley J, <strong>Specht S.<\/strong> Axonal transport of phospholipid in goldfish optic system. Exp. Neurol. 1975;46:261\u2011281.<\/li>\n<li><strong>Specht SC.<\/strong> Axonal transport in the optic system of neonatal and adult hamsters following injection of 3H\u2011fucose into the eye. Exp. Neurol. 1977;54:352\u2011368.<\/li>\n<li><strong>Specht SC.<\/strong> Transneuronal transfer of radioactive substances during postnatal development of the hamster visual system. Exp. Neurol. 1980; 69:213\u2011225.<\/li>\n<li><strong>Specht SC. <\/strong>Postnatal changes in enzyme activities in synaptosomes isolated from hamster optic nerve endings. J.Neurochem. 1982;39:310\u2011314.<\/li>\n<li><strong>Specht SC<\/strong>. Axonal transport of Na,K\u2011ATPase in optic nerve of hamster. Current Topics in Membranes and Transport 19. 1983; 819-823.<\/li>\n<li><strong>Specht SC<\/strong>, Sweadner KJ. Rapid axonal transport of two molecular forms of Na,K\u2011ATPase in optic nerve of albino rats. Proc. Nat. Acad. Sci. USA 1984;81,1234-1238.<\/li>\n<li><strong>Specht SC.<\/strong> Development and regional distribution of two molecular forms of the catalytic subunit of the Na,K\u2011ATPase in rat brain. Biochem. Biophys. Res. Comm. 1984;121, 208-212.<\/li>\n<li><strong>Specht SC.<\/strong> Postnatal changes in subcellular localization of 3H\u2011fucosyl glycoproteins axonally transported into hamster optic nerve endings. Neurochem. Res. 1984;9,59-71.<\/li>\n<li><strong>Specht SC<\/strong>, Castro S, Vizcarra N. Characteristics of alpha and alpha(+) in rat brain. in The Sodium Pump, The Company of Biologists, Ltd, Cambridge, Edited by I. Glynn and C. Ellory, 1985; pp. 165\u2011170.<\/li>\n<li><strong>Specht SC,<\/strong> Del Valle E, Castro Hernandez S. Increased in vivo synthesis of Na pump isoforms after pre\u2011treatment with citrate buffer. in The Na,+K+\u2011Pump, Part B: Cellular Aspects Edited by Skou and Maunsbach, 1988;pp. 143\u2011147.<\/li>\n<li><strong>Specht SC. <\/strong>Molecular isoforms of the sodium in brain. Puerto Rico Health Sciences Journal. 1988;7: 189\u2011194.<\/li>\n<li>Lopez-Rosado and <strong>Corey, S (S. Specht)<\/strong>. A ouabain-sensitive Na,k-ATPase in the sea anemone Stoichactis helianthus. Preliminary characterization. In The Sodium Pump:Recent Developments. J.H. Kaplan and P. De Weer, editors. The Rockefeller University Press, New York, 1991; 489 -492.<\/li>\n<li><strong>Specht S<\/strong>, Martin J, Gaud, E, De Hoyos J. Molecular isoforms of Na\/K-ATPase in the nervous system and kidney of the spontaneously diabetic BB\/Wor rat. Biochim. Biophys. Acta 1991; 1118:77-82.<\/li>\n<li><strong>Corey-Specht S<\/strong>, Lopez-Rosado R, Santos-Berrios C, Figueroa-Nieves R. A ouabain-sensitive Na,K-ATPase in tentacles of the sea anemone Stichodactyla helianthus. Comp. Biochem. Physiol. pt B, 1995;110:555-563.<\/li>\n<li><strong>Specht SC<\/strong>, Rodriguez C, Qui\u00f1ones L, Velazquez S. Effect of High Ionic Strength and Inhibitors of H,K-ATPase on the Ouabain-sensitive K-p-Nitrophenyl Phosphatase Activity in the Sea Anemone Stichodactyla Comp. Biochem. Physiol. pt B, 1997; 117B: 217-224.<\/li>\n<li><strong>Corey (Specht) S.<\/strong> Recent developments in the therapeutic potential of cannabinoids. PRHSJ. 2005;24:27-34.<\/li>\n<li>Woolcock K, <strong>\u00a0Specht SC. <\/strong>Modulation of Na, K-ATPase activity by prostaglandin E<sub>1 <\/sub>and [D\u2011Ala<sup>2<\/sup>,N\u2011Me\u2011Phe<sup>4<\/sup>,Gly<sup>5<\/sup>-ol]\u2011enkephalin Life Sciences 2006; Mar 6;78(15):1653-61.<\/li>\n<li>Arystarkhova E, Donnet C, Munoz-Matta A, <strong>Specht S<\/strong>, Sweadner KJ. Multiplicity of expression of FXYD proteins in mammalian cells: dynamic exchange of phospholemman and gamma subunit in response to stress.Am J Physiol Cell Physiol. 2007; 292 (3): C1179-91.<\/li>\n<li>Gonzalez-Tejera GM and<strong> Corey S.<\/strong> CYP2D6 Genotypes in Puerto Rican Psychiatry Patients with Intolerance of Antidepressants and Antipsychotics. Bol Assn Med PR. 2009.<\/li>\n<li>Gaedigk A, Gonzalez-Tejera G, <strong>Corey S<\/strong>. <em>CYP2D6*31<\/em> sequence update. CYP2D6 allele nomenclature [database on the Internet]. <strong><em>Human Cytochrome P450 (CYP) Allele Nomenclature Committee <\/em><\/strong>[cited 2009 Mar 27]. Available from: <a href=\"http:\/\/www.cypalleles.ki.se\/cyp2d6.htm\">http:\/\/www.cypalleles.ki.se\/cyp2d6.htm<\/a>.<\/li>\n<li>Gaedigk A, Garc\u00eda MI, Pearce RE, S\u00e1nchez S, Garc\u00eda-Solaesa V, Lorenzo-Romo C , Gonzalez-Tejera G, <strong>Corey S<\/strong>. Discovery of the non-functional <em>CYP2D6*31 <\/em>allele in Spanish, Puerto Rican and US Hispanic populations. Eur J Clin Pharmacol. 2010 Sep;66(9):859-64. Epub 2010 May 16.<\/li>\n<li>Gonzalez Tejera G, Gaedigk A, <strong>Corey S<\/strong>. Genetic variants of the drug-metabolizing enzyme <em>CYP2D6<\/em> in Puerto Ricans: Implications for breast cancer patients. Puerto Rico Health Sci J. 2010; 29(3):299-304.<\/li>\n<li>Karla Claudio-Campos, Carmelo Orengo-Mercado, Jessicca Y. Renta, Muriel Peguero, Ricardo Garc\u00eda, Gabriel Hern\u00e1ndez, <strong>Susan Corey<\/strong>, Carmen L. Cadilla, and Jorge Duconge Pharmacogenetics of healthy volunteers in Puerto Rico Drug Metabol Personal Ther. 2015 Dec 1; 30(4): 239\u2013249.<\/li>\n<li>V\u00e9lez-Pastrana S, Campos-Colberg M, Gonz\u00e1lez-Sanchez J, George R, Campos-Colberg V,\u00a0 L\u00f3pez B, <strong>Susan Corey-Best.<\/strong> Non-Fatal Opioid Overdose and Abuse Visits to a University Hospital Emergency Department in Puerto Rico, 2009-2018. Puerto Rico Health Sci Journal. (June 2022).<\/li>\n<\/ul>\n<p><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Kinase modulation of Na Pump<\/p>\n","protected":false},"featured_media":1469,"comment_status":"closed","ping_status":"closed","template":"","dt_team_category":[34],"class_list":["post-870","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-faculty","dt_team_category-34","description-off"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team\/870","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/types\/dt_team"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/comments?post=870"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/media\/1469"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/media?parent=870"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/pharmacology\/wp-json\/wp\/v2\/dt_team_category?post=870"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}