{"id":67,"date":"2014-04-22T14:51:14","date_gmt":"2014-04-22T14:51:14","guid":{"rendered":"http:\/\/md.rcm.upr.edu\/rai\/?page_id=67"},"modified":"2026-01-20T11:44:25","modified_gmt":"2026-01-20T15:44:25","slug":"peer-reviewed-publications","status":"publish","type":"page","link":"https:\/\/md.rcm.upr.edu\/rai\/rheumatology-section\/peer-reviewed-publications\/","title":{"rendered":"Peer-Reviewed Publications"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<h2><span style=\"color: #800000;\">2025<\/span><\/h2>\n<p>Serrano-Arroyo L, Gonz\u00e1lez-Mel\u00e9ndez A, R\u00edos-Rivera R, Rodr\u00edguez-Gonz\u00e1lez V, Vil\u00e1 LM. Impact of SARS-CoV-2 pre-delta\/delta and omicron variants on clinical outcomes in a systemic lupus erythematosus cohort from Puerto Rico. Lupus. 2025 Apr;34(4):415-424.<\/p>\n<p>L\u00f3pez LA, Vil\u00e1 LM. Dual Autoimmunity: A Case Report of the Sequential Development of Systemic Lupus Erythematosus in a Patient With Anti-MDA5 Dermatomyositis. Cureus. 2025 May 7;17(5):e83686.<\/p>\n<p>Rios G, P\u00e9rez-R\u00edos N. Association of 6-Minute Walk Test (6MWT) Data with Cardiopulmonary Factors in Hispanic Systemic Sclerosis Patients. P R Health Sci J. 2025 Jun;44(2):111-115.<\/p>\n<p>Martinez VS, Gonzalez-Ramos KN, Rios G. Massive Ascites as an Initial Presentation of Systemic Lupus Erythematosus in the Absence of Significant Proteinuria: A Case Report. Cureus. 2025 Aug 22;17(8):e90750.<\/p>\n<p>Gonz\u00e1lez-Ramos K, Bret\u00f3n JM, Vil\u00e1 LM. Lymphoma presenting as autoimmune rheumatic disorder: clinical overlap and diagnostic considerations. Ann Med Surg (Lond). 2025 Oct 7;87(12):8426-8433.<\/p>\n<p>Rodr\u00edguez Nazario I, Vil\u00e1 LM, Melin K. Feasibility and acceptability of incorporating telemedicine into pharmacy services in the rheumatology clinics of the School of Medicine of the University of Puerto Rico. Am J Health Syst Pharm. 2025 Nov 12:zxaf311. Epub ahead of print.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h2><span style=\"color: #800000;\">2024<\/span><\/h2>\n<p>R\u00edos G, Gonz\u00e1lez-Ramos K, Figueroa-D\u00edaz A, Gonz\u00e1lez-Mel\u00e9ndez A. Pemphigus vulgaris unmasked in a patient with Beh\u00e7et&#8217;s disease: A complex diagnostic dilemma. Cureus. 2024 Sep 26;16(9):e70253.<\/p>\n<p>\u00c1lvarez P\u00e9rez LF, Gonz\u00e1lez-Mel\u00e9ndez A, Vil\u00e1 LM. Severe gingival inflammation and bleeding as the sole manifestation of granulomatosis with polyangiitis. BMJ Case Rep. 2024 Aug 22;17(8):e261013.<\/p>\n<p>Rodriguez-Perez N. Systemic lupus erythematosus in a nonagenarian woman: A case report. Cureus. 2024 Sep 20;16(9):e69812.<\/p>\n<p>Rivera-Burgos I, Vil\u00e1 LM. Severe antiphospholipid syndrome and diffuse glomerulonephritis after adalimumab treatment in a patient with ulcerative colitis. Case Rep Rheumatol. 2024 Nov 4;2024:8024757[\/vc_column_text][vc_column_text]<\/p>\n<h2><span style=\"color: #800000;\">2023<\/span><\/h2>\n<p>Ugarte-Gil MF, Dubey J, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS. Association of Systemic Lupus International Collaborating Clinics Frailty Index With Damage in Systemic Lupus Erythematosus Patients: Results From a Multiethnic, Multicenter US Cohort of Patients With Lupus. Arthritis Care Res (Hoboken). 2023 Mar;75(3):585-589.<\/p>\n<p>Amaral JK, Bingham CO 3rd, Taylor PC, Vil\u00e1 LM, Weinblatt ME, Schoen RT. Pathogenesis of chronic chikungunya arthritis: Resemblances and links with rheumatoid arthritis. Travel Med Infect Dis. 2023 Mar-Apr;52:102534.<\/p>\n<p>Gonz\u00e1lez-Mel\u00e9ndez A, B\u00e1ez-Negr\u00f3n L, R\u00edos-Rivera R, Franco-O&#8217;Connell AS, Nieves-Plaza M, Vil\u00e1 LM. Short- and mid-term outcomes in systemic lupus erythematosus patients presenting with disease exacerbation after SARS-CoV-2 mRNA vaccination: A cohort study from Puerto Rico. Lupus. 2023 Apr;32(4):571-579.<\/p>\n<p>R\u00edos-Rivera RA, Vil\u00e1 LM. Coexistent Relapsing Polychondritis and Clinically Amyopathic Dermatomyositis: A Rare Association of Autoimmune Disorders. Case Rep Rheumatol. 2023 Apr 11;2023:3719502.<\/p>\n<p>Vil\u00e1 LM, Nieves-Plaza M, Torres XV, Nieves B, Washington AV. Anti-Triggering Receptor Expressed on Myeloid Cells-Like Transcript-1 Antibodies in Systemic Lupus Erythematosus. Eur J Rheumatol. 2023 Apr;10(2):88-89.<\/p>\n<p>L\u00f3pez-Candales A, Sawalha K, Vila LM. Inflammasomes as potential mediators of adverse cardiovascular events in diabetes and lupus: more questions than answers. J Cardiovasc Med (Hagerstown). 2023 May 1;24(5):279-282.<\/p>\n<p>Borgia RE, Ugarte-Gil MF, Vil\u00e1 LM, Reveille JD, McGwin G Jr, Alarc\u00f3n GS. Health-Related Quality of Life in Adults With Adolescent- and Adult-Onset Systemic Lupus Erythematosus: A Longitudinal Study of a Multiethnic US Cohort. Arthritis Care Res (Hoboken). 2023 Jul;75(7):1416-1422.<\/p>\n<p>Amaral JK, Bingham CO, Taylor PC, Vil\u00e1 LM, Weinblatt ME, Schoen RT. Therapy for Chikungunya Arthritis: A Study of 133 Brazilian Patients. Am J Trop Med Hyg. 2023 Aug 7;109(3):542-547.<\/p>\n<p>Vil\u00e1 LM, Lebr\u00f3n-Torres L. Efficacy of Milk Thistle in a Patient with Systemic Lupus Erythematosus Presenting with Autoimmune Hepatitis. Int J Clin Stu Med Case Rep 2023 Aug 10; 29(1): 001.<\/p>\n<p>\u00c1lvarez P\u00e9rez LF, Vila S. Exacerbation of Behcet&#8217;s Disease and Pyoderma Gangrenosum Following COVID-19 Infection: A Case Report. Cureus. 2023 Nov 25;15(11):e49386.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span style=\"color: #800000;\">2022<\/span><\/h2>\n<p>M\u00e1rquez S, Vil\u00e1 LM. Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus. Case Rep Rheumatol. 2022 Jan 7;2022:9506733.<\/p>\n<p>B\u00e1ez-Negr\u00f3n L, Vil\u00e1 LM. New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination. Case Rep Rheumatol. 2022 Feb 11;2022:6436839.<\/p>\n<p>Santiago A, Crespo-Ramos SM, Correa-Rivas M, Vil\u00e1 LM. Monarticular rheumatoid arthritis of the elbow. BMJ Case Rep. 2022 Mar 7;15(3):e246863.<\/p>\n<p>Rivera R, Vil\u00e1 S. An Unusual Case of Kidney Injury in a Young Woman with a Connective Tissue Disease. Case Rep Nephrol. 2022 May 30;2022:3833649.<\/p>\n<p>Borgia RE, Ugarte-Gil MF, Vil\u00e1 LM, Reveille JD, McGwin G Jr, Alarc\u00f3n GS. Health-Related Quality of Life in Adults with Adolescent- and Adult-onset Systemic Lupus Erythematosus: A Longitudinal Study of a Multiethnic US Cohort (LUMINA LXXXIV). Arthritis Care Res (Hoboken). 2022 Aug 30. Epub ahead of print.<\/p>\n<p>Ugarte-Gil MF, Dubey J, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS. Association of Systemic Lupus International Collaborating Clinics Frailty Index with Damage in Systemic Lupus Erythematosus Patients: Results from a Multiethnic, Multicenter US Cohort of Patients with Lupus. Arthritis Care Res (Hoboken). 2022 Mar 7. Epub ahead of print.<\/p>\n<p>Amaral JK, Bingham CO 3rd, Taylor PC, Vil\u00e1 LM, Weinblatt ME, Schoen RT. Pathogenesis of chronic chikungunya arthritis: Resemblances and links with rheumatoid arthritis. Travel Med Infect Dis. 2022 Dec 20; 52:102534. Epub ahead of print.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span style=\"color: #800000;\">2021<\/span><\/h2>\n<p>Gonz\u00e1lez-Mel\u00e9ndez A, Medina-Parrilla EJ, V\u00e9lez R, Vil\u00e1 LM. Isolated intestinal polyarteritis nodosa in an elderly patient. BMJ Case Rep. 2021 Mar 4;14(3):e241431.<\/p>\n<p>Medina-Cintr\u00f3n N, Mart\u00ednez I, P\u00e9rez-R\u00edos N, Berr\u00edos-L\u00f3pez Y, Vil\u00e1 LM. Clinical Manifestations and Outcomes in Disease-Modifying Antirheumatic Drug-Naive Adult Patients with Chronic Chikungunya Arthritis. Am J Trop Med Hyg. 2021 Mar 8;104(5):1741\u20136.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Griffin R, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Achievement of the 2019 European Alliance of Associations for Rheumatology\/American College of Rheumatology Criteria for Systemic Lupus Erythematosus and Amount of Damage Accrual: Results From a Multiethnic Multicenter Cohort. Arthritis Care Res (Hoboken). 2021 Jul;73(7):1038-1040.<\/p>\n<p>Jolly M, Sehgal V, Arora S, Azizoddin D, Pinto B, Sharma A, Devilliers H, Inoue M, Toloza S, Bertoli A, Blazevic I, Vil\u00e1 LM, Moldovan I, Torralba KD, Mazzoni D, Cicognani E, Hasni S, Goker B, Haznedaroglu S, Bourre-Tessier J, Navarra SV, Clarke A, Weisman M, Wallace D, Mok CC. Does hydroxychloroquine improve patient reported outcomes in patients with lupus? Lupus. 2021 Oct;30(11):1790-1798.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Harvey GB, Vil\u00e1 LM, Griffin R, Alarc\u00f3n GS. Applying the 2019 European Alliance of Associations for Rheumatology\/American College of Rheumatology Lupus Criteria to Patients From the LUMINA Cohort: Results From the Multiethnic, Multicenter US Cohort. Arthritis Care Res (Hoboken). 2021 Oct;73(10):1451-1455.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span style=\"color: #800000;\">2020<\/span><\/h2>\n<p>Pons-Estel GJ, Ugarte-Gil MF, Harvey GB, Wojdyla D, Quintana R, Saurit V, Soriano ER, Bonfa E, Massardo L, Cardiel M, Vila LM, Griffin R, Pons-Estel BA, Alarc\u00f3n GS; Grupo Latino Americano De Estudio de Lupus (GLADEL). Applying the 2019 EULAR\/ACR lupus criteria to patients from an established cohort: a Latin American perspective. RMD Open. 2020 Jan;6(1): e001097.<\/p>\n<p>Cintr\u00f3n D, Alanis JM, \u00c1lvarez-Villalobos N, Rodr\u00edguez-Guti\u00e9rrez R, Vil\u00e1 LM. A systematic review of pharmacological therapies and their effectiveness on health-related quality of life outcomes in patients with juvenile-onset systemic lupus erythematosus. Lupus. 2020 Mar;29(3):303-310.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Griffin R, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Patients Who Do Not Fulfill the 2019 EULAR\/ACR Criteria for Systemic Lupus Erythematosus Accrue Less Damage. Arthritis Care Res (Hoboken). 2020 Apr 15. doi: 10.1002\/acr.24213. Epub ahead of print.<\/p>\n<p>V\u00e1zquez-Otero I, Medina-Cintr\u00f3n N, Arroyo-\u00c1vila M, Gonz\u00e1lez-Sep\u00falveda L, Vil\u00e1 LM. Clinical impact of hydroxychloroquine dose adjustment according to the American Academy of Ophthalmology guidelines in systemic lupus erythematosus. Lupus Sci Med. 2020 May;7(1):e000395.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Harvey GB, Vil\u00e1 LM, Griffin R, Alarc\u00f3n GS. Applying the 2019 EULAR\/ACR Lupus Criteria to Patients from the LUMINA Cohort. Arthritis Care Res (Hoboken). 2020 Jun 29. doi: 10.1002\/acr.24367. Epub ahead of print.<\/p>\n<p>Jord\u00e1n-Gonz\u00e1lez P, Gago-Pi\u00f1ero R, Varela-Rosario N, P\u00e9rez-R\u00edos N, Vil\u00e1 LM. Characterization of a subset of patients with primary Sj\u00f6gren&#8217;s syndrome initially presenting with C3 or C4 hypocomplementemia. Eur J Rheumatol. 2020 Jul;7(3):112-117.<\/p>\n<p>Gonz\u00e1lez-Mel\u00e9ndez A, Fred-Jim\u00e9nez RM, Arroyo-\u00c1vila M, D\u00edaz-Correa L, P\u00e9rez-R\u00edos N, Rodr\u00edguez N, R\u00edos G, Vil\u00e1 LM. Incident arterial vascular events in a cohort of Puerto Ricans with rheumatoid arthritis. SAGE Open Med. 2020 Sep 15;8:2050312120958844.<\/p>\n<p>Jord\u00e1n-Gonz\u00e1lez P, Gago-Pi\u00f1ero R, V\u00e1zquez-Sanabria I, P\u00e9rez-R\u00edos N, Vil\u00e1 LM. Factors Associated With Disease Damage in Puerto Ricans With Primary Sj\u00f6gren Syndrome. J Clin Rheumatol. 2020 Oct;26(7S Suppl 2):S101-S105.<\/p>\n<h2><span style=\"color: #800000;\">2019<\/span><\/h2>\n<p>Alarc\u00f3n GS, Ugarte-Gil MF, Pons-Estel G, Vil\u00e1 LM, Reveille JD, McGwin G Jr. Remission and low disease activity state (LDAS) are protective of intermediate and long-term outcomes in SLE patients. Results from LUMINA (LXXVIII), a multiethnic, multicenter US cohort.\u00a0 Lupus. 2019 Mar;28(3):423-426.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Vila LM, McGwin G, Alarc\u00f3n GS. Time in remission and low disease activity state (LDAS) are associated with a better quality of life in patients with systemic lupus erythematosus: results from LUMINA (LXXIX), a multiethnic, multicentre US cohort. RMD Open. 2019 May 23;5(1): e000955.<\/p>\n<p>Jolly M, Sethi B, O&#8217;Brien C, Sequeira W, Block JA, Toloza S, Bertoli A, Blazevic I, Vil\u00e1 LM, Moldovan I, Torralba KD, Cicognani E, Mazzoni D, Hasni S, Goker B, Haznedaroglu S, Bourre-Tessier J, Navarra SV, Mok CC, Clarke A, Weisman M, Wallace D. Drivers of satisfaction with care for patients with lupus. ACR Open Rheumatol. 2019 Nov 6;1(10): 649-656.<\/p>\n<p>Jolly M, Sequeira W, Block JA, Toloza S, Bertoli A, Blazevic I, Vila LM, Moldovan I, Torralba KD, Mazzoni D, Cicognani E, Hasni S, Goker B, Haznedaroglu S, Bourre-Tessier J, Navarra SV, Mok CC, Weisman M, Clarke AE, Wallace D, Alarc\u00f3n G. Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2019 Dec;71(12):1647-1652.<\/p>\n<p>Santiago-Casas Y, Vil\u00e1 LM. Etiolog\u00eda e Inmunopatog\u00e9nesis del lupus eritematoso sist\u00e9mico. In: Bases de la Inmunolog\u00eda Cl\u00ednica. Segunda Edici\u00f3n. Editor: Jos\u00e9 L. Aguilar Olano, Sociedad Peruana de Reumatolog\u00eda, Per\u00fa 2019.<\/p>\n<p>Jord\u00e1n-Gonz\u00e1lez P, Gago-Pi\u00f1ero R, V\u00e1zquez-Sanabria I, P\u00e9rez-R\u00edos N, Vil\u00e1 LM. Factors associated with disease damage in Puerto Ricans with primary Sjogren syndrome. J Clin Rheumatol. 2019 Mar 12. doi: 10.1097\/RHU.0000000000001023.<\/p>\n<p>Alarc\u00f3n GS, Ugarte-Gil MF, Pons-Estel G, Vil\u00e1 LM, Reveille JD, McGwin G Jr. Remission and low disease activity state (LDAS) are protective of intermediate and long-term outcomes in SLE patients. Results from LUMINA (LXXVIII), a multiethnic, multicenter US cohort.\u00a0 Lupus. 2019 Mar;28(3):423-426.<\/p>\n<p>Ugarte-Gil MF, Pons-Estel GJ, Vila LM, McGwin G, Alarc\u00f3n GS. Time in remission and low disease activity state (LDAS) are associated with a better quality of life in patients with systemic lupus erythematosus: results from LUMINA (LXXIX), a multiethnic, multicentre US cohort. RMD Open. 2019 May 23;5(1): e000955.<\/p>\n<p>Jolly M, Sethi B, O&#8217;Brien C, Sequeira W, Block JA, Toloza S, Bertoli A, Blazevic I, Vil\u00e1 LM, Moldovan I, Torralba KD, Cicognani E, Mazzoni D, Hasni S, Goker B, Haznedaroglu S, Bourre-Tessier J, Navarra SV, Mok CC, Clarke A, Weisman M, Wallace D. Drivers of satisfaction with care for patients with lupus. ACR Open Rheumatol. 2019 Nov 6;1(10): 649-656.<\/p>\n<p>Jolly M, Sequeira W, Block JA, Toloza S, Bertoli A, Blazevic I, Vila LM, Moldovan I, Torralba KD, Mazzoni D, Cicognani E, Hasni S, Goker B, Haznedaroglu S, Bourre-Tessier J, Navarra SV, Mok CC, Weisman M, Clarke AE, Wallace D, Alarc\u00f3n G. Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2019 Dec;71(12):1647-1652.<\/p>\n<p>Santiago-Casas Y, Vil\u00e1 LM. Etiolog\u00eda e Inmunopatog\u00e9nesis del lupus eritematoso sist\u00e9mico. In: Bases de la Inmunolog\u00eda Cl\u00ednica. Segunda Edici\u00f3n. Editor: Jos\u00e9 L. Aguilar Olano, Sociedad Peruana de Reumatolog\u00eda, Per\u00fa 2019.<\/p>\n<h2><span style=\"color: #800000;\">2018<\/span><\/h2>\n<p>Gago R, Vil\u00e1 S, V\u00e9lez-Rivera J, Vil\u00e1 LM. Severe systemic inflammatory response syndrome immediately after spinal surgery in a patient with axial gout. BMJ Case Rep. 2018 Jan 24; 2018. pii: bcr-2017-222474.<\/p>\n<p>Cruz-P\u00e9rez F, Vil\u00e1 S, R\u00edos G, Vil\u00e1 LM. Efficacy of cyclosporine in a systemic lupus erythematosus patient presenting with macrophage activating syndrome. Case Rep Rheumatol 2018 Jan 15;2018:1961585.<\/p>\n<p>Patel Z, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC,Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP,Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarc\u00f3n GS, Martin J, Reveille JD,Anaya JM, James JA, Sivils KL, Criswell LA, Vil\u00e1 LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA,Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA,Alarc\u00f3n-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, HarleyJB, Kottyan LC. A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 Apr 18. doi: 10.1093\/hmg\/ddy140. [Epub ahead of print]<\/p>\n<p>Jolly M, Sequeira W, Block JA, Toloza S, Bertoli A, Blazevic I, Vil\u00e1 LM, Moldovan I, Torralba K, Mazzoni D, Cicognani E,\u00a0 Hasni S, Kaya A, Goker B, Tezcan M, Haznedaroglu S, Bourre-Tessier J, Navarra S, Mok CC, Weisman M, Clarke A, Wallace D, Alarc\u00f3n GS. Gender differences in quality of life in patients with systemic lupus. Arthritis Care Res (Hoboken). 2018 Apr 25. doi: 10.1002\/acr.23588. [Epub ahead of print]<\/p>\n<p>Jord\u00e1n-Gonz\u00e1lez P, Shum LM, Gonz\u00e1lez-Sep\u00falveda L, Vil\u00e1 LM. Clinical correlates and outcomes in a group of Puerto Ricans with systemic lupus erythematosus hospitalized due to severe infections. SAGE Open Med. 2018 May 21;6:2050312118778385.<\/p>\n<p>V\u00e1zquez-Otero I, Rodr\u00edguez-Navedo Y, Vil\u00e1-Rivera K, Nieves-Plaza M, Washington AV, Vil\u00e1 LM. Association of soluble TREM-like transcript-1 with clinical features and patient reported outcomes in systemic lupus erythematosus. Eur J Rheumatol. 2018 Dec;5(4):244-248.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span style=\"color: #800000;\">2017<\/span><\/h2>\n<p>Gago R, Shum LM, Vil\u00e1 LM. Right upper quadrant abdominal pain as the initial presentation of polyarteritis nodosa. BMJ Case Rep. 2017 Feb 22; 2017. pii:bcr2016218019.<\/p>\n<p>Arroyo-\u00c1vila M, Cab\u00e1n A, Garc\u00eda-Rivera EJ, Irizarry-P\u00e9rez M, Torres H, Gorbea H, Vil\u00e1 LM. Clinical manifestations associated with peripheral joint involvement in patients with acute chikungunya virus infection. Am J Trop Med Hyg. 2017 Apr; 96(4):916-921.<\/p>\n<p>Zuo Y, Willis R, Papalardo E, Petri M, Harris EN, Schleh A, DeCeulaer K, Smikle M, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, Gonzalez EB. A unique antiphospholipid assay recognizing phospholipid mixture compared with criteria antiphospholipid immunoassays in lupus patients. Lupus. 2017 May; 26(6):606-615.<\/p>\n<p>Ugarte-Gil MF, Pimentel-Quiroz VR, Vil\u00e1 LM, Reveille JD, McGwin G Jr, Alarc\u00f3n GS. Factors associated with disease expression patterns in systemic lupus erythematosus patients: results from LUMINA (LXXVII), a multiethnic US cohort.Lupus. 2017 May; 26(6):650-655.<\/p>\n<p>Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Alml\u00f6f JC, Acevedo-V\u00e1squez EM, Alarc\u00f3n GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D&#8217;Alfonso S, Da Silva BM, de la R\u00faa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frosteg\u00e5rd J, Garc\u00eda MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kov\u00e1cs L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Cece\u00f1a MA, Mart\u00edn J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sj\u00f6wall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusi\u00e9-Luna T, Vasconcelos C, Vil\u00e1 LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syv\u00e4nen AC, R\u00f6nnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarc\u00f3n-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney\u00a0 PM, Vyse TJ. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 Jul 17; 8:16021.<\/p>\n<p>Vil\u00e1 S. Inflammation in Osteoarthritis. P R Health Sci J. 2017 Sep; 36(3):123-129.<\/p>\n<p>Montes-Rivera G, R\u00edos G, Vil\u00e1 LM. Efficacy of rituximab in a systemic lupus erythematosus patient presenting with diffuse alveolar hemorrhage. Case Rep Rheumatol. 2017; 2017:6031053.<\/p>\n<p>Varela-Rosario N,\u00a0 Arroyo-\u00c1vila M, Fred-Jim\u00e9nez RM, D\u00edaz-Correa LM, P\u00e9rez-R\u00edos N, Rodr\u00edguez N, <sup>\u00a0<\/sup>R\u00edos G, Vil\u00e1 LM. Long-term outcomes in Puerto Ricans with rheumatoid arthritis (RA) receiving early treatment with disease-modifying anti-rheumatic drugs using the American College of Rheumatology definition of early RA. Open Rheumatol J. 2017; 11:136-144.<\/p>\n<h2><span style=\"color: #800000;\">2016<\/span><\/h2>\n<p>Zhao J, Giles BM, Taylor RL, Yette GA, Lough KM, Ng HL, Abraham LJ, Wu H, Kelly JA, Glenn SB, Adler AJ, Williams AH, Comeau ME, Ziegler JT, Marion M, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Alarc\u00f3n GS, Anaya JM, Bae SC, Kim D, Lee HS, Criswell LA, Freedman BI, Gilkeson GS, Guthridge JM, Jacob CO,James JA, Kamen DL, Merrill JT, Sivils KM, Niewold TB, Petri MA, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Vil\u00e1 LM, Vyse TJ, Kaufman KM, Harley JB, Langefeld CD, Gaffney PM, Brown EE, Edberg JC, Kimberly RP, Ulgiati D, Tsao BP, Boackle SA. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan;75(1):242-52.<\/p>\n<p>Deng Y, Zhao J, Sakurai D, Sestak AL, Osadchiy V, Langefeld CD, Kaufman KM, Kelly JA, James JA, Petri MA, Bae SC, Alarc\u00f3n-Riquelme ME, Alarc\u00f3n GS, Anaya JM,Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vil\u00e1 LM, Sohn II, Lee S, Chang DM, Song YW, Vyse TJ, Harley JB,Brown EE, Edberg JC, Kimberly RP, Cantor RM, Hahn BH, Grossman JM, Tsao BP.Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013.<\/p>\n<p>Fred-Jim\u00e9nez RM, Arroyo-\u00c1vila M, Mayor \u00c1M, R\u00edos G, Vil\u00e1 LM. Clinical manifestations associated with overweight\/obesity in Puerto Ricans with fibromyalgia syndrome. J Obes. 2016;2016:1379289. doi: 10.1155\/2016\/1379289. Epub 2016 Jan 18.<\/p>\n<p>Varela-Rosario N, P\u00e9rez-Berenguer JL, Vil\u00e1 LM. Efficacy of immunosuppressive treatment in a systemic lupus erythematosus patient presenting with inclusion body myositis. BMJ Case Rep. 2016 Apr 5;2016. pii: bcr2016215035. doi: 10.1136\/bcr-2016-215035.<\/p>\n<p>V\u00e1zquez-Sanabria IL, Vil\u00e1 LM. Sustained improvement of fibromyalgia syndrome after electroconvulsive therapy for intractable depression. J Clin Rheumatol. 2016 Aug;22(5):289-90.<\/p>\n<p>Gamarra-Hilburn F, R\u00edos G, Vil\u00e1 LM. Septic olecranon bursitis caused by <em>Candida parapsilosis<\/em> in a patient with rheumatoid arthritis. Case Rep Rheumatol 2016;2016:2019250.<\/p>\n<p>Rodr\u00edguez-Rivera DV, Rodr\u00edguez-Navedo Y, Nieves-Plaza M, Vil\u00e1 LM. Patient-reported outcome measures in a population of medically indigent patients with systemic lupus erythematosus in Puerto Rico. SAGE Open Med. 2016 Sep 23;4:2050312116670927.<\/p>\n<h2><span style=\"color: #800000;\">2015<\/span><\/h2>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Vil\u00e1 LM. Cardiac tamponade in a patient with mixed connective tissue disease. J Clin Rheumatol. 2015 Jan;21(1):42-5. Review.<\/p>\n<p style=\"text-align: justify;\">Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM,Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarc\u00f3n GS, Reveille JD, Anaya JM, James JA, Moser KL, Criswell LA, Vil\u00e1 LM, Alarc\u00f3n-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Binjoo Y, Choi J, Bae SC, Boackle SA, Vyse TJ, Guthridge JM, Namjou B, Gaffney PM, Langefeld CD, Kaufman KM, Kelly JA, Harley IT, Harley JB, Kottyan LC. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet. 2015 Jan 8; 5:450.<\/p>\n<p style=\"text-align: justify;\">Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X,Bowman S; UK Primary Sj\u00f6gren&#8217;s Syndrome Registry, Rischmueller M, Lester S, Brun JG, G\u00f8ransson LG, Harboe E, Omdal R, Cunninghame-Graham DS, Vyse T, Miceli-Richard C, Brennan MT, Lessard JA, Wahren-Herlenius M, Kvarnstr\u00f6m M, Illei GG, Witte T, Jonsson R, Eriksson P, Nordmark G, Ng WF; UK Primary Sj\u00f6gren&#8217;s Syndrome Registry, Anaya JM, Rhodus NL, Segal BM, Merrill JT, James JA, Guthridge JM, Scofield RH, Alarcon-Riquelme M, Bae SC, Boackle SA, Criswell LA, Gilkeson G, Kamen DL, Jacob CO, Kimberly R, Brown E, Edberg J, Alarc\u00f3n GS, Reveille JD, Vil\u00e1 LM, Petri M, Ramsey-Goldman R, Freedman BI, Niewold T, Stevens AM, Tsao BP, Ying J, Mayes MD, Gorlova OY, Wakeland W, Radstake T, Martin E, Martin J, Siminovitch K, Moser Sivils KL, Gaffney PM, Langefeld CD, Harley JB, Kaufman KM. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96.<\/p>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Fred-Jim\u00e9nez RM, Vil\u00e1 LM. Early-onset neutropenia induced by rituximab in a patient with lupus nephritis and hemolytic anemia. Case Rep Rheumatol. 2015; 2015:616787.<\/p>\n<p style=\"text-align: justify;\">Martins M, Williams AH, Comeau M, Marion M, Ziegler JT, Freedman BI, Merrill JT, Glenn SB, Kelly JA, Sivils KM, James JA, Guthridge JM, Alarc\u00f3n-Riquelme ME, Bae SC, Kim JH, Kim D, Anaya JM, Boackle SA, Criswell LA, Kimberly RP, Alarc\u00f3n GS, Brown EE, Vil\u00e1 LM, Petri MA, Ramsey-Goldman R, Niewold TB, Tsao BP, Gilkeson GS, Kamen DL, Jacob CO, Stevens AM, Gaffney PM, Harley JB, Langefeld CD, Fesel C. Genetic association of CD247 (CD3\u03b6) with SLE in a large-scale multiethnic study. Genes Immun. 2015 Mar; 16(2):142-50.<\/p>\n<p style=\"text-align: justify;\">Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarc\u00f3n GS, Reveille JD, Anaya JM,James JA, Sivils KL, Criswell LA, Vil\u00e1 LM, Alarc\u00f3n-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 7; 96(5):731-9.<\/p>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Vil\u00e1 LM. Rheumatic Manifestations in patients with chikungunya infection. P R Health Sci J. 2015 Jun; 34(2):71-7. Review.<\/p>\n<p style=\"text-align: justify;\">V\u00e1zquez-Sanabria IL, Mercado-Seda R, Varela-Rosario N, Vil\u00e1 LM. Efficacy of intravenous immunoglobulins in a patient with systemic lupus erythematosus presenting with Stevens-Johnson syndrome. BMJ Case Rep. 2015 Jul 22; 2015. pii: bcr2015211157.<\/p>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Santiago-Casas Y, McGwin G Jr, Cantor RS, Petri M, Ramsey-Goldman R, Reveille JD, Kimberly RP, Alarc\u00f3n GS, Vil\u00e1 LM, Brown EE. Clinical associations of anti-Smith antibodies in PROFILE: a multi-ethnic lupus cohort. Clin Rheumatol. 2015 Jul; 34(7):1217-23.<\/p>\n<p style=\"text-align: justify;\">Zhao J, Wu H, Langefeld CD, Kaufman KM, Kelly JA, Bae SC; Marta E. Alarc\u00f3n-Riquelme for the BIOLUPUS and GENLES networks, Alarc\u00f3n GS, Anaya JM,Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, James JA, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Petri MA, Song ST, Jeong HJ, Ramsey Goldman R,Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vil\u00e1 LM, Chang DM, Song YW, Vyse TJ, Harley JB, Brown EE, Edberg JC, Kimberly RP, Hahn BH, Grossman JM, Tsao BP, La Cava A. Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol. 2015 Dec; 161(2):157-62.<\/p>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Vil\u00e1 LM. Reply to \u201cRheumatic manifestations in patients with chikungunya infection: Comment on the article by Arroyo-\u00c1vila and Vil\u00e1\u201d. P R Health Sci J. 2015 Dec: 34(4): 232.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2014<\/span><\/h2>\n<p style=\"text-align: justify;\">Willis R, Seif AM, McGwin Jr G, Martinez-Martinez LA, Gonzalez EB, Doan E, Dang N, Papalardo E, Liu J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, Pierangeli SS. Effects of statins on proinflammatory\/prothrombotic biomarkers and on disease activity scores in SLE patients: data from LUMINA (LXXVI), a multi-ethnic US cohort. Clin Exp Rheumatol. 2014 Mar-Apr; 32(2):162-7.<\/p>\n<p style=\"text-align: justify;\">Ojeda J, L\u00f3pez-L\u00f3pez L, Gonz\u00e1lez A, Vil\u00e1 LM. Infective endocarditis initially presenting with a dermatomyositis-like syndrome. BMJ Case Rep. 2014 Jan10; 2014 (jan10_1). pii: bcr2013200865.<\/p>\n<p style=\"text-align: justify;\">Fajardo-Hermosillo LD, Rodr\u00edguez-Navedo Y, Nadal AJ, Vil\u00e1 LM. Lymphocyte sensitivity assay as a marker for glucocorticoid resistance in lupus: report of two sisters with systemic lupus erythematosus. Lupus. 2014; 23(1):88-92.<\/p>\n<p style=\"text-align: justify;\">Villafr\u00e1dez-D\u00edaz M, Santiago-Casas Y, Nieves-Plaza M,\u00a0 Morales M, Vanessa Rodr\u00edguez V,\u00a0 R\u00edos G, Mart\u00ednez D, Vil\u00e1 LM. Association of the use of statins with disease activity and functional status in Puerto Ricans with rheumatoid arthritis. P R Health Sci J 2014; Mar; 33(1):3-8.<\/p>\n<p style=\"text-align: justify;\">Guthridge JM, Lu R, Sun H, Sun C, Wiley GB, Dominguez N, Macwana SR, Lessard CJ, Kim-Howard X, Cobb BL, Kaufman KM, Kelly JA, Langefeld CD, Adler AJ, Harley IT, Merrill JT, Gilkeson GS, Kamen DL, Niewold TB, Brown EE, Edberg JC, Petri MA,Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Kimberly RP, Freedman BI, Stevens AM, Boackle SA, Criswell LA, Vyse TJ, Behrens TW, Jacob CO, Alarc\u00f3n-Riquelme ME, Sivils KL, Choi J, Joo YB, Bang SY, Lee HS, Bae SC, Shen N, Qian X, Tsao BP, Scofield RH, Harley JB, Webb CF, Wakeland EK, James JA, Nath SK, Graham RR,Gaffney PM. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 3; 94(4):586-98.<\/p>\n<p style=\"text-align: justify;\">Dong C, Ptacek TS, Redden DT, Zhang K, Brown EE, Edberg JC, McGwin G, Alarc\u00f3n GS, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Petri M, Qin A, Wu J, Kimberly RP. Fc\u03b3RIIIa SNPs and haplotypes affect human IgG binding and association with lupus nephritis in African Americans. Arthritis Rheumatol 2014. 2014 May; 66(5):1291-9.<\/p>\n<p style=\"text-align: justify;\">D\u00edaz-Correa LM, Ram\u00edrez-Garc\u00eda LM; Castro-Santana LE, Vil\u00e1 LM. Osteoporosis knowledge in patients with a first fragility fracture in Puerto Rico. Bol Asoc Med P R. 2014; 106(1):6-10.<\/p>\n<p style=\"text-align: justify;\">R\u00edos G, Ojeda J, Rodr\u00edguez-Navedo Y. Thrombosed aneurysm as the initial manifestation of Takayasu arteritis. BMJ Case Rep. 2014 Jun 9; 2014. pii: bcr2013203523.<\/p>\n<p style=\"text-align: justify;\">Font YM, Castro-Santana LE, Nieves-Plaza M, Maldonado M, Mayor AM, MD, Vil\u00e1 LM. Factors associated with regional\u00a0 rheumatic pain syndromes in Puerto Ricans with diabetes mellitus. Clin Rheumatol 2014. Jul; 33(7):995-1000.<\/p>\n<p style=\"text-align: justify;\">Kaiser R, Tang LF, Taylor KE, Sterba K, Nititham J, Brown EE, Edberg JC, McGwin G Jr, Alarc\u00f3n GS, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Petri M, Rauch J, Miller E, Mesznick K, Kwok PY, Kimberly RP, Salmon JE, Criswell LA. A Polymorphism in TLR2 is Associated with Arterial Thrombosis in a Multi-Ethnic SLE Population Arthritis Rheumatol 2014. Jul; 66(7):1882-7.<\/p>\n<p style=\"text-align: justify;\">R\u00edos G, Estrada M, Mayor AM, Vil\u00e1 LM. Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J. 2014 Sep; 33(3):112-6.<\/p>\n<p style=\"text-align: justify;\">D\u00edaz-Correa LM, R\u00edos G, Vil\u00e1 LM. Granulomatosis with polyangiitis complicated with bronchopleural fistula. BMJ Case Rep. 2014 Sep 23;2014. pii: bcr2014205145.<\/p>\n<p style=\"text-align: justify;\">L\u03ccpez L\u03ccpez L, Nieves-Plaza M, Castro M, Font Y, Vil\u00e1 LM, Ayala-Torres S. Mitochondrial DNA damage in systemic lupus erythematosus: Association with major organ involvement and damage accrual. Lupus. 2014 Oct; 23(11):1133-41.<\/p>\n<p style=\"text-align: justify;\">Arroyo-\u00c1vila M, Vil\u00e1, LM. Limited systemic sclerosis initially presenting with mesenteric panniculitis. BMJ Case Rep. 2014 Oct 17; 2014. pii: bcr2014206961.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2013<\/span><\/h2>\n<p style=\"text-align: justify;\">Nieves-Plaza M, Castro-Santana LE, Font YM, Mayor AM, Vil\u00e1 LM. Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico. J Clin Rheumatol. 2013 Jan;19(1):1-6.<\/p>\n<p style=\"text-align: justify;\">Kaiser R, Taylor KE, Deng Y, Zhao J, Li Y, Nititham J, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarc\u00f3n GS, Ramsey-Goldman R, Reveille JD, Vila LM, Petri M, Kimberly RP, Feng X, Sun L, Shen N, Li W, Lu JX,Wakeland EK, Li QZ, Yang W, Lau YL, Liu FL, Chang DM, Yu CY, Song YW, Tsao BP,Criswell LA; Hwee Siew Howe and the Tan Tock Seng Hospital Systemic Lupus Erythematosus Study Group. Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians. Arthritis Rheum. 2013 Jan;65(1):211-5.<\/p>\n<p style=\"text-align: justify;\">Negr\u00f3n AM, D\u00edaz-Correa LM, Gago R, Mayor AM, Mart\u00ednez A, Vil\u00e1 S, Vil\u00e1 LM. Rheumatology practice profiles in teaching and community settings in Puerto Rico:implications to subspecialty training. J Clin Rheumatol. 2013 Mar;19(2):67-71.<\/p>\n<p style=\"text-align: justify;\">Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, Comeau ME, Marion MC, Glenn SB, Cantor RM, Grossman JM, Hahn BH, Song YW, Yu CY, James JA, Guthridge JM, Brown EE, Alarc\u00f3nGS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri MA, Reveille JD, Vil\u00e1 LM,Anaya JM, Boackle SA, Stevens AM, Freedman BI, Criswell LA, Pons Estel BA; Argentine Collaborative Group, Lee JH, Lee JS, Chang DM, Scofield RH, Gilkeson GS, Merrill JT, Niewold TB, Vyse TJ, Bae SC, 14. Alarc\u00f3n-Riquelme ME; BIOLUPUS network, Jacob CO, Moser Sivils K, Gaffney PM, Harley JB, Sawalha AH, Tsao BP. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.<\/p>\n<p style=\"text-align: justify;\">Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS, Vyse TJ, Pons-Estel BA; Argentine Collaborative Group, Freedman BI, Gaffney PM, Sivils KM, James JA, Gregersen PK, Anaya JM, Niewold TB, Merrill JT, Criswell LA, Stevens AM, Boackle SA, Cantor RM,Chen W, Grossman JM, Hahn BH, Harley JB, Alarc\u03ccn-Riquelme ME; BIOLUPUS and GENLES networks, Brown EE, Tsao BP. MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet. 2013; 9(2):e1003336.<\/p>\n<p style=\"text-align: justify;\">Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarc\u00f3n GS, Edberg JC, Petri M,Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Freedman BI, Tsao BP, Criswell LA, Jacob CO, Moore JH, Vyse TJ, Langefeld CL, Guthridge JM, Gaffney PM, Moser KL, Scofield RH, Alarc\u00f3n-Riquelme ME; BIOLUPUS Network, Williams SM, Merrill JT, James JA,Kaufman KM, Kimberly RP, Harley JB, Nath SK. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis,inflammation, and autoantibody production. PLoS Genet. 2013;9(2):e1003222.<\/p>\n<p style=\"text-align: justify;\">Santiago-Casas Y, Peredo RA, Vil\u00e1 LM. Efficacy of low-dose intravenous cyclophosphamide in systemic lupus erythematosus presenting with Guillain-Barre syndrome-like acute axonal neuropathies: report of two cases. Lupus. 2013 Mar; 22(3):324-7. PubMed PMID: 23439473<\/p>\n<p style=\"text-align: justify;\">Jolly M, Toloza S, Block J, Mikolaitis R, Kosinski M, Wallace D, Durran-Barragan S, Bertoli A, Blazevic I, Vil\u00e1 L, Cooray D, Moldovan I, Katsaros E, Weisman M, Torralba KM, Alarc\u00f3n G. Spanish LupusPRO: cross-cultural validationstudy for lupus. Lupus. 2013 Apr; 22(5):431-6.<\/p>\n<p style=\"text-align: justify;\">Fajardo-Hermosillo LD, L\u00f3pez-L\u00f3pez L, Nadal A, Vil\u00e1 LM. Multifocal osteonecrosis in systemic lupus erythematosus: case report and review of the literature. BMJ Case Rep. 2013 Apr 16; 2013. doi:pii: bcr2013008980.<\/p>\n<p style=\"text-align: justify;\">Rodr\u00edguez-P\u00e9rez N, Rodr\u00edguez-Navedo Y, Font YM, Vil\u00e1 LM. Inflammatory myopathy as the initial presentation of cryoglobulinaemic vasculitis. BMJ Case Rep. 2013 Jun 3; 2013. doi:pii: bcr2013010117.<\/p>\n<p style=\"text-align: justify;\">Ramos PS, Oates JC, Kamen DL, Williams AH, Gaffney PM, Kelly JA, Kaufman KM, Kimberly RP, Niewold TB, Jacob CO, Tsao BP, Alarc\u00f3n GS, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, James JA, Guthridge JM, Merrill JT, Boackle SA, Freedman BI, Scofield RH, Stevens AM, Vyse TJ, Criswell LA, Moser KL, Alarc\u00f3n-Riquelme ME, Langefeld CD, Harley JB, Gilkeson GS. Variable Association of Reactive Intermediate Genes with Systemic Lupus Erythematosus in Populations with Different African Ancestry. J Rheumatol. 2013 Jun; 40(6):842-849.<\/p>\n<p style=\"text-align: justify;\">Santiago-Casas Y, Gonz\u00e1lez-Rivera T, Castro-Santana L, R\u00edos G, Mart\u00ednez D, Rodr\u00edguez V, Gonz\u00e1lez-Alcover R, Mayor AM, Vil\u00e1 LM. Impact of managed care health insurance system for indigent patients with rheumatoid arthritis in Puerto Rico. Clin Rheumatol. 2013 Jun; 32(6):763-9.<\/p>\n<p style=\"text-align: justify;\">Jim\u00e9nez-Encarnaci\u00f3n E, Vil\u00e1 LM. Recurrent venous thrombosis in Ehlers Danlos syndrome type III: an atypical manifestation. BMJ Case Rep. 2013 Jun 27; 2013.doi:pii: bcr2013008922.<\/p>\n<p style=\"text-align: justify;\">Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarc\u00f3n GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vil\u00e1 LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B; Argentine Collaborative Group, Niewold TB, Moser Sivils KL, Merrill JT, Anaya JM, Gilkeson GS, Gaffney PM, Bae SC, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Harley JB, Criswell LA, James JA, Nath SK. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013 Aug 7;8(8):e69404. doi: 10.1371\/journal.pone.0069404.<\/p>\n<p style=\"text-align: justify;\">Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G\u2019sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW. ABIN1 dysfunction as a genetic basis for lupus nephritis. J Am Soc Nephrol. 2013 Nov;24(11):1743-54.<\/p>\n<p style=\"text-align: justify;\">Murthy V, Willis R, Romay-Penabad Z, Ruiz-Lim\u00f3n P, Mart\u00ednez-Mart\u00ednez LA, Jatwani S, Jajoria P, Seif A, Alarc\u00f3n GS, Papalardo E, Liu J, Vil\u00e1 LM, McGwin G Jr, McNearney TA, Maganti R, Sunkureddi P, Parekh T, Tarantino M, Akhter E, Fang H, Gonzalez EB, Binder WR, Norman GL, Shums Z, Teodorescu M, Reveille JD, Petri M, Pierangeli SS. Value of Isolated IgA Anti-\u03b22 -Glycoprotein I Positivity in the Diagnosis of the Antiphospholipid Syndrome. Arthritis Rheum. 2013 Dec; 65(12):3186-93.<\/p>\n<p style=\"text-align: justify;\">Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc\u03ccn-Riquelme ME; BIOLUPUS and GENLES networks, Edberg JC, Kimberly RP, Ramsey-Goldman R, Petri MA, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS, Kaufman KM, Vyse TJ, Jacob CO, Gaffney PM, Sivils KM, James JA, Kamen DL, Gilkeson GS, Niewold TB, Merrill JT, Scofield RH, Criswell LA, Stevens AM, Boackle SA, Kim JH, Choi J, Pons-Estel BA; Argentine Collaborative Group, Freedman BI, Anaya JM, Martin J, Yu CY, Chang DM, Song YW, Langefeld CD, Chen W, Grossman JM, Cantor RM, Hahn BH, Tsao BP. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013;9(10):e1003870.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1-Rivera K, Jim\u00e9nez-Encarnaci\u00f3n E, Vil\u00e1-P\u00e9rez S. Pulmonary hemorrhage in a patient initially presenting with discoid lupus. P R Health S J. 2013 Dec; 32(4):203-205.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2012<\/span><\/h2>\n<p style=\"text-align: justify;\">Hughes T, Adler A, Kelly JA, Kaufman KM, Williams AH, Langefeld CD, Brown EE, Alarc\u00f3n GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Boackle SA, Stevens AM, Reveille JD, Sanchez E, Mart\u00edn J, Niewold TB, Vil\u00e1 LM, Scofield RH, Gilkeson GS, Gaffney PM, Criswell LA, Moser KL, Merrill JT, Jacob CO, Tsao BP, James JA, Vyse TJ, Alarc\u00f3n-Riquelme ME; BIOLUPUS Network, Harley JB, Richardson BC, Sawalha AH. Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum. 2012 Feb;64(2):485-92.<\/p>\n<p style=\"text-align: justify;\">Lin CP, Adrianto I, Lessard CJ, Kelly JA, Kaufman KM, Guthridge JM, Freedman BI, Anaya JM, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Pons-Estel BA, Martin J, Glenn S, Adler A, Bae SC, Park SY, Bang SY, Song YW, Boackle SA, Brown EE, Edberg JC, Alarc\u00f3n GS, Petri MA, Criswell LA, Ramsey-Goldman R, Reveille JD, Vila LM, Gilkeson GS, Kamen DL, Ziegler J, Jacob CO, Rasmussen A, James JA, Kimberly RP, Merrill JT, Niewold TB, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Moser KL, Harley JB, Gaffney PM, Montgomery CG. Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis. Genes Immun. 2012 Apr;13(3):232-8.<\/p>\n<p style=\"text-align: justify;\">Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ, Alarc\u00f3n-Riquelme ME, Alarc\u00f3n GS, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Cho SK, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Kim JH, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Scofield RH, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Kaufman KM, Harley JB, Wakeland EK, Langefeld CD, Gaffney PM, Montgomery CG, Moser KL; BIOLUPUS Network; GENLES Network. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 6;90(4):648-60.<\/p>\n<p style=\"text-align: justify;\">Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarc\u00f3n GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Criswell LA, Vil\u00e1 LM, Jacob CO, Gaffney PM, Moser KL, Vyse TJ, Alarc\u00f3n-Riquelme ME; BIOLUPUS Network, James JA, Tsao BP, Scofield RH, Harley JB, Richardson BC, Sawalha AH. Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis. 2012 May;71(5):694-9.<\/p>\n<p style=\"text-align: justify;\">Santiago-Casas Y, Vil\u00e1 LM, McGwin G Jr, Cantor RS, Petri M, Ramsey-Goldman R, Reveille JD, Kimberly RP, Alarc\u00f3n GS, Brown EE. Association of discoid lupus erythematosus with clinical manifestations and damage accrual in a multiethnic lupus cohort. Arthritis Care Res (Hoboken). 2012 May;64(5):704-12.<\/p>\n<p style=\"text-align: justify;\">Jim\u00e9nez-Encarnaci\u00f3n E, Garc\u00eda-Pallas MV, Vil\u00e1 LM. Severe leg ulcers in a multiple myeloma patient with cryoglobulinemic vasculitis. P R Health Sci J. 2012 Jun;31(2):71.<\/p>\n<p style=\"text-align: justify;\">Namjou B, Choi CB, Harley IT, Alarc\u00f3n-Riquelme ME; BIOLUPUS Network, Kelly JA, Glenn SB, Ojwang JO, Adler A, Kim K, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown EE, Edberg J, Alarc\u00f3n GS, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Kim EM, Park SY, Sung YK, Guthridge JM, Merrill JT, Petri M, Ramsey-Goldman R, Vil\u00e1 LM, Niewold TB, Martin J, Pons-Estel BA; Genoma en Lupus Network, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams AH, Comeau ME, Reveille JD, Kang C, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Bae SC. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9.<\/p>\n<p style=\"text-align: justify;\">Wang S, Adrianto I, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Alarc\u00f3n GS,Anaya JM, Bae SC, Kim JH, Joo YB, Boackle SA, Brown EE, Petri MA, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Wakeland EK, Moser KL, Montgomery CG, Gaffney PM. A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul;13(5):380-7.<\/p>\n<p style=\"text-align: justify;\">L\u00f3pez-L\u00f3pez L, Gonz\u00e1lez A, Vil\u00e1 LM. Long-term membranous glomerulonephritis as the presenting manifestation of systemic lupus erythematosus in a patient with human immunodeficiency virus infection. Lupus. 2012 Jul; 21(8):900-4.<\/p>\n<p style=\"text-align: justify;\">Willis R, Seif AM, McGwin G Jr, Martinez-Martinez LA, Gonz\u00e1lez EB, Dang N, Papalardo E, Liu J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, Pierangeli SS. Effect of hydroxychloroquine treatment on pro-inflammatory cytokines and disease activity in SLE patients: data from LUMINA (LXXV), a multiethnic US cohort. Lupus. 2012 Jul; 21(8):830-5.<\/p>\n<p style=\"text-align: justify;\">Kaiser R, Li Y, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G Jr, Alarc\u00f3n GS, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Petri MA, Kimberly RP, Taylor KE, Criswell LA. Genetic risk factors for thrombosis in systemic lupus erythematosus. J Rheumatol. 2012 Aug;39(8):1603-10.Epub 2012 Jun 15.<\/p>\n<p style=\"text-align: justify;\">L\u00f3pez-L\u00f3pez L, Rivera-Rodr\u00edguez N, Vil\u00e1 LM. Nitrofurantoin-induced microangiopathic haemolytic anaemia and thrombocytopaenia in a patient with systemic lupus erythematosus. BMJ Case Rep. 2012 Sep 12; 2012.<\/p>\n<p style=\"text-align: justify;\">S\u00e1nchez E, Rasmussen A, Riba L, Acevedo-Vasquez E, Kelly JA, Langefeld CD, Williams AH, Ziegler JT, Comeau ME, Marion MC, Garc\u00eda-De La Torre I, Maradiaga-Cece\u00f1a MA, Cardiel MH, Esquivel-Valerio JA, Rodriguez-Amado J, Moctezuma JF, Miranda P, Perandones CE, Castel C, Laborde HA, Alba P, Musuruana JL, Goecke IA, Anaya JM, Kaufman KM, Adler A, Glenn SB, Brown EE, Alarc\u00f3n GS, Kimberly RP, Edberg JC, Vil\u00e1 LM, Criswell LA, Gilkeson GS, Niewold TB, Mart\u00edn J, Vyse TJ, Boackle SA, Ramsey-Goldman R, Scofield RH, Petri M, Merrill JT, Reveille JD, Tsao BP, Orozco L, Baca V, Moser KL, Gaffney PM, James JA, Harley JB, Tusi\u00e9-Luna T, Pons-Estel BA, Jacob CO, Alarc\u00f3n-Riquelme ME. Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum. 2012 Nov;64(11):3687-94.<\/p>\n<p style=\"text-align: justify;\">Adrianto I, Wang S, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Alarc\u00f3n GS, Anaya JM, Bae SC, Kim JH, Joo YB, Boackle SA, Brown EE, Petri MA, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Mart\u00edn J, Merrill JT, Niewold TB, Pons-EstelBA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Wakeland EK, Moser KL, Montgomery CG, Gaffney PM. Association of two independentfunctional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov;64(11):3695-705.<\/p>\n<p style=\"text-align: justify;\">Kim K, Brown EE, Choi CB, Alarc\u00f3n-Riquelme ME; BIOLUPUS, Kelly JA, Glenn SB, Ojwang JO, Adler A, Lee HS, Boackle SA, Criswell LA, Alarc\u00f3n GS, Edberg JC, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Guthridge JM, Nath SK, Richardson B, Sawalha AH, Kang YM, Shim SC, Suh CH, Lee SK, Kim CS, Merrill JT, Petri M, Ramsey-Goldman R, Vil\u00e1 LM, Niewold TB, Martin J, Pons Estel BA; GENLES, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams A, Comeau M,Reveille JD, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Kang C, Kimberly RP, Bae SC. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis. 2012 Nov;71(11):1809-14.<\/p>\n<p style=\"text-align: justify;\">Jim\u00e9nez-Encarnaci\u00f3n E, R\u00edos G, Mu\u00f1oz-Mirabal A, Vil\u00e1 LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep. 2012 Dec 19;2012.PubMed PMID: 23257938.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2011<\/span><\/h2>\n<p style=\"text-align: justify;\">Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, Williams AH, Gallant CJ; Marta E. Alarc\u00f3n-Riquelme on behalf of the BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Bruner GR, Langefeld CD, Montgomery C, Harley JB, Scofield RH, Gaffney PM, Moser KL. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet. 2011 Jan 7;88(1):83-91<\/p>\n<p style=\"text-align: justify;\">Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Bang SY, Boackle SA, Brown EE, Petri MA, Gallant C, Ramsey-Goldman R, Reveille JD, Vila LM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Moser KL, Webb CF, Humphrey MB, Montgomery CG, Gaffney PM. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar;43(3):253-8<\/p>\n<p style=\"text-align: justify;\">Zhao J, Wu H, Khosravi M, Cui H, Qian X, Kelly JA, Kaufman KM, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Adler A, Glenn SB,Alarc\u00f3n-Riquelme ME; BIOLUPUS Network; GENLES Network, Pons-Estel BA, Harley JB, Bae SC, Bang SY, Cho SK, Jacob CO, Vyse TJ, Niewold TB, Gaffney PM, Moser KL, Kimberly RP, Edberg JC, Brown EE, Alarcon GS, Petri MA, Ramsey-Goldman R, Vil\u00e1 LM, Reveille JD, James JA, Gilkeson GS, Kamen DL, Freedman BI, Anaya JM, Merrill JT, Criswell LA, Scofield RH, Stevens AM, Guthridge JM, Chang DM, Song YW, Park JA, Lee EY, Boackle SA, Grossman JM, Hahn BH, Goodship TH, Cantor RM, Yu CY, Shen N, Tsao BP. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet. 2011 May;7(5):e1002079<\/p>\n<p style=\"text-align: justify;\">Hughes T, Kim-Howard X, Kelly JA, Kaufman KM, Langefeld CD, Ziegler J, Sanchez E, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Mart\u00edn J, Brown EE, Vil\u00e1 LM, Alarc\u00f3n GS, James JA, Gilkeson GS, Moser KL, Gaffney PM, Merrill JT, Vyse TJ, Alarc\u00f3n-Riquelme ME; BIOLUPUS Network, Nath SK, Harley JB, Sawalha AH. Fine-mapping and transethnic genotyping establish IL2\/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis Rheum. 2011 Jun;63(6):1689-97<\/p>\n<p style=\"text-align: justify;\">Namjou B, Kothari PH, Kelly JA, Glenn SB, Ojwang JO, Adler A, Alarc\u00f3n-Riquelme ME, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown E, Edberg J, Stevens AM, Jacob CO, Tsao BP, Gilkeson GS, Kamen DL, Merrill JT, Petri M, Goldman RR, Vila LM, Anaya JM, Niewold TB, Martin J, Pons-Estel BA, Sabio JM, Callejas JL, Vyse TJ, Bae SC, Perrino FW, Freedman BI, Scofield RH, Moser KL, Gaffney PM, James JA, Langefeld CD, Kaufman KM, Harley JB, Atkinson JP. Evaluation of theTREX1 gene in a large multi-ancestral lupus cohort. Genes Immun. 2011Jun;12(4):270-9<\/p>\n<p style=\"text-align: justify;\">Nieves-Plaza M, Ortiz AP, Col\u00f3n M, Molina MJ, Castro-Santana LE, Rodr\u00edguez VE, Mayor AM, Vil\u00e1 LM. Outcome and predictors of kidney disease progression in Puerto Ricans with systemic lupus erythematosus initially presenting with mild renal involvement. J Clin Rheumatol. 2011 Jun; 17(4):179-84<\/p>\n<p style=\"text-align: justify;\">Ramos PS, Williams AH, Ziegler JT, Comeau ME, Guy RT, Lessard CJ, Li H, Edberg JC, Zidovetzki R, Criswell LA, Gaffney PM, Graham DC, Graham RR, Kelly JA, Kaufman KM, Brown EE, Alarc\u00f3n GS, Petri MA, Reveille JD, McGwin G, Vil\u00e1 LM, Ramsey-Goldman R, Jacob CO, Vyse TJ, Tsao BP, Harley JB, Kimberly RP, Alarc\u00f3n-Riquelme ME, Langefeld CD, Moser KL. Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus. Arthritis Rheum. 2011 Jul;63(7):2049-57.<\/p>\n<p style=\"text-align: justify;\">Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Bae SC, Lee JH, Lee JS, Chang DM, Song YW, Yu CY, Kimberly RP, Edberg JC, Brown EE, Petri MA, Ramsey-Goldman R, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n-Riquelme ME, Harley JB, Boackle SA, Stevens AM, Scofield RH, Merrill JT, Freedman BI, Anaya JM, Criswell LA, Jacob CO, Vyse TJ, Niewold TB, Gaffney PM, Moser KL, Gilkeson GS, Kamen DL, James JA, Grossman JM, Hahn BH, Tsokos GC, Tsao BP, Alarc\u00f3n GS; BIOLUPUS Network; GENLES Network. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep;63(9):2755-63.<\/p>\n<p style=\"text-align: justify;\">Sanchez E, Nadig A, Richardson BC, Freedman BI, Kaufman KM, Kelly JA, Niewold TB, Kamen DL, Gilkeson GS, Ziegler JT, Langefeld CD, Alarc\u00f3n GS, Edberg JC, Ramsey-Goldman R, Petri M, Brown EE, Kimberly RP, Reveille JD, Vil\u00e1 LM, Merrill JT, Anaya JM, James JA, Pons-Estel BA, Martin J, Park SY, Bang SY, Bae SC, Moser KL, Vyse TJ, Criswell LA, Gaffney PM, Tsao BP, Jacob CO, Harley JB, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES, Sawalha AH. Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis. 2011 Oct;70(10):1752-7.<\/p>\n<p style=\"text-align: justify;\">S\u00e1nchez E, Comeau ME, Freedman BI, Kelly JA, Kaufman KM, Langefeld CD, Brown EE, Alarc\u00f3n GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Vil\u00e1 LM, Merrill JT, Tsao BP, Kamen DL, Gilkeson GS, James JA, Vyse TJ; International Consortium on the Genetics of Systemic Lupus Erythematosus, Gaffney PM, Jacob CO, Niewold TB, Richardson BC, Harley JB, Alarc\u00f3n-Riquelme ME, Sawalha AH. Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum. 2011 Nov;63(11):3493-501.<\/p>\n<p style=\"text-align: justify;\">L\u00f3pez-L\u00f3pez L, Vil\u00e1 LM. Atypical subtrochanteric fractures associated with long-term use of bisphosphonates. P R Health Sci J. 2011 Dec; 30(4):211.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2010<\/span><\/h2>\n<p style=\"text-align: justify;\">Zhang J, Gonz\u00e1lez LA, Roseman JM, Vil\u00e1 LM, Reveille JD, Al\u00e1rcon GS. Predictors of the rate of change in disease activity over time in LUMINA, a multiethnic US cohort of patients with systemic lupus erythematosus: LUMINA LXX. Lupus. 2010;19(6):727-33.<\/p>\n<p style=\"text-align: justify;\">Pons-Estel GJ, Alarc\u00f3n GS, Gonz\u00e1lez LA, Zhang J, Vil\u00e1 LM, Reveille JD, McGwin G Jr; Lumina Study Group. Possible protective effect of hydroxychloroquine on delaying the occurrence of integument damage in lupus: LXXI, data from a multiethnic cohort. Arthritis Care Res (Hoboken). 2010 Mar;62(3):393-400.<\/p>\n<p style=\"text-align: justify;\">Burgos PI, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS. Factors predictive of thrombotic events in LUMINA, a multi-ethnic cohort of SLE patients (LXXII). Rheumatology (Oxford). 2010 Sep;49(9):1720-5.<\/p>\n<p style=\"text-align: justify;\">Santiago-Casas Y, Gonz\u00e1lez-Rivera TC, Castro-Santana LE, R\u00edos G, Mart\u00ednez D, Rodr\u00edguez VE, Gonz\u00e1lez-Alcover R, Mayor AM, Vil\u00e1 LM. Impact of age on clinical manifestations and outcome in Puerto Ricans with rheumatoid arthritis. Ethn Dis. 2010 Winter;20(1 Suppl 1):S1-191-5.<\/p>\n<p style=\"text-align: justify;\">Castro-Santana LE, Col\u00f3n M, Molina MJ, Rodr\u00edguez VE, Mayor AM, Vil\u00e1 LM. Efficacy of two cyclophosphamide regimens for the treatment of lupus nephritis in Puerto Ricans: low vs. standard dose. Ethn Dis. 2010 Winter;20(1 Suppl1):S1-116-21.<\/p>\n<p style=\"text-align: justify;\">R\u00edos G, Mayor AM. Clinical and sociodemographic features of Puerto Ricans with systemic sclerosis. Ethn Dis. 2010 Winter;20(1 Suppl 1):S1-185-9.<\/p>\n<p style=\"text-align: justify;\">Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarc\u00f3n GS, Brown EE, McGwin G Jr, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Langefeld CD, Kimberly RP. The Non-Muscle Myosin Heavy Chain 9 Gene (MYH9) Is Not Associated with Lupus Nephritis in African Americans. Am J Nephrol. 2010 Jun 7;32(1):66-72.<\/p>\n<p style=\"text-align: justify;\">R\u00edos G, Peredo RA. Lymphocytic mastitis preceding Sj\u00f6gren\u2019s syndrome. P R Health Sci J. 2010 Jun;29(2):127-9.<\/p>\n<p style=\"text-align: justify;\">Burgos PI, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Brown EE, Alarcon GS. Is familial lupus different from sporadic lupus? Data from LUMINA (LXXIII), a multiethnic US cohort. Lupus. 2010 Oct;19(11):1331-6.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2009<\/span><\/h2>\n<p style=\"text-align: justify;\">Santiago-Casas Y, Vil\u00e1 LM. Pulmonary Hemorrhage in Patients with Systemic Lupus Erythematosus. Curr Respir Med Rev. 2009 Feb; 5(1): 49-54.<\/p>\n<p style=\"text-align: justify;\">Gonz\u00e1lez LA, Pons-Estel GJ, Zhang JS, McGwin G Jr, Roseman J, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS, LUMINA Study Group. Effect of age, menopause and cyclophosphamide use on damage accrual in systemic lupus erythematosus patients from LUMINA, a multiethnic US cohort (LUMINA LXIII). Lupus. 2009 Feb; 18(2):184-6.<\/p>\n<p style=\"text-align: justify;\">Sanchez ML, McGwin G Jr, Dur\u00e1n S, Fern\u00e1ndez M, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS; LUMINA Study Group. Factors predictive of overall health over the course of the disease in patients with systemic lupus erythematosus from the LUMINA cohort (LXII): use of the SF-6D. Clin Exp Rheumatol. 2009 Jan-Feb; 27(1):67-71.<\/p>\n<p style=\"text-align: justify;\">Webb R, Wren JD, Jeffries M, Kelly JA, Kaufman KM, Tang Y, Frank MB, Merrill J, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Alarc\u00f3n GS, Vil\u00e1 LM, Alarc\u00f3n-Riquelme ME, James JA, Vyse TJ, Moser KL, Gaffney PM, Gilkeson GS, Harley JB, Sawalha AH. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 2009 Apr; 60(4):1076-84.<\/p>\n<p style=\"text-align: justify;\">Jacob CO, Zhu J, Armstrong DL, Yan M, Han J, Zhou XJ, Thomas JA, Reiff A, Myones BL, Ojwang JO, Kaufman KM, Klein-Gitelman M, McCurdy D, Wagner Weiner L, Silverman E, Ziegler J, Kelly JA, Merrill JT, Harley JB, Ramsey-Goldman R, Vila LM, Bae SC, Vyse TJ, Gilkeson GS, Gaffney PM, Moser KL, Langefeld CD, Zidovetzki R, Mohan C. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2009 Apr14; 106(15):6256 61.<\/p>\n<p style=\"text-align: justify;\">Danila MI, Pons-Estel GJ, Zhang J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Renal damage is the most important predictor of mortality within the damage index: data from LUMINA LXIV, a multiethnic US cohort. Rheumatology (Oxford). 2009 May; 48(5):542-5.<\/p>\n<p style=\"text-align: justify;\">Pons-Estel GJ, Alarc\u00f3n GS, McGwin G Jr, Danila MI, Zhang J, Bastian HM, Reveille JD, Vil\u00e1 LM; Lumina Study Group. Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohort. Arthritis Rheum. 2009 Jun 15; 61(6):830-9.<\/p>\n<p style=\"text-align: justify;\">Lu R, Vidal GS, Kelly JA, Delgado-Vega AM, Howard XK, Macwana SR, Dominguez N, Klein W, Burrell C, Harley IT, Kaufman KM, Bruner GR, Moser KL, Gaffney PM, Gilkeson GS, Wakeland EK, Li QZ, Langefeld CD, Marion MC, Divers J, Alarc\u00f3n GS, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Reveille JD, McGwin G Jr, Vil\u00e1 LM, Petri MA, Bae SC, Cho SK, Bang SY, Kim I, Choi CB, Martin J, Vyse TJ, Merrill JT, Harley JB, Alarc\u00f3n-Riquelme ME; BIOLUPUS and GENLES Multicenter Collaborations, Nath SK, James JA, Guthridge JM. Genetic associations of LYN with systemic lupus erythematosus. Genes Immun. 2009 Jul;10(5):397-403.<\/p>\n<p style=\"text-align: justify;\">Guo L, Deshmukh H, Lu R, Vidal GS, Kelly JA, Kaufman KM, Dominguez N, Klein W, Kim-Howard X, Bruner GR, Scofield RH, Moser KL, Gaffney PM, Dozmorov IM, Gilkeson GS, Wakeland EK, Li QZ, Langefeld CD, Marion MC, Williams AH, Divers J, Alarc\u00f3n GS, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Reveille JD, McGwin G Jr, Vil\u00e1 LM, Petri MA, Vyse TJ, Merrill JT, James JA, Nath SK, Harley JB, Guthridge JM. Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population. Genes Immun. 2009 Jul;10(5):531-8.<\/p>\n<p style=\"text-align: justify;\">Pons-Estel GJ, Gonz\u00e1lez LA, Zhang J, Burgos PI, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS. Predictors of cardiovascular damage in patients with systemic lupus erythematosus: data from LUMINA (LXVIII), a multiethnic US cohort. Rheumatology (Oxford). 2009 Jul;48(7):817-22.<\/p>\n<p style=\"text-align: justify;\">Gonz\u00e1lez LA, Pons-Estel GJ, Zhang J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA study group. Time to neuropsychiatric damage occurrence in LUMINA (LXVI): a multi-ethnic lupus cohort. Lupus. 2009 Aug;18(9):822-30.<\/p>\n<p style=\"text-align: justify;\">Webb R, Merrill JT, Kelly JA, Sestak A, Kaufman KM, Langefeld CD, Ziegler J, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Alarc\u00f3n GS, Vil\u00e1 LM, Alarc\u00f3n-Riquelme ME, James JA, Gilkeson GS, Jacob CO, Moser KL, Gaffney PM, 110. Vyse TJ, Nath SK, Lipsky P, Harley JB, Sawalha AH. A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum. 2009 Aug;60(8):2402-7.<\/p>\n<p style=\"text-align: justify;\">Burgos PI, Alarc\u00f3n GS, McGwin G Jr, Crews KQ, Reveille JD, Vil\u00e1 LM. Disease activity and damage are not associated with increased levels of fatigue in systemic lupus erythematosus patients from a multiethnic cohort: LXVII. Arthritis Rheum. 2009 Sep 15;61(9):1179-86.<\/p>\n<p style=\"text-align: justify;\">Douglas KB, Windels DC, Zhao J, Gadeliya AV, Wu H, Kaufman KM, Harley JB, Merrill J, Kimberly RP, Alarc\u00f3n GS, Brown EE, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Vil\u00e1 LM, Gaffney PM, James JA, Moser KL, Alarc\u00f3n-Riquelme ME, Vyse TJ, Gilkeson GS, Jacob CO, Ziegler JT, Langefeld CD, Ulgiati D, Tsao BP, Boackle SA. Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing. Genes Immun. 2009 Jul;10(5):457-69.<\/p>\n<p style=\"text-align: justify;\">Pons-Estel BA, S\u00e1nchez-Guerrero J, Romero-D\u00edaz J, Iglesias-Gamarra A, Bonfa E, Borba EF, Shinjo SK, Bernatsky S, Clarke A, Garc\u00eda MA, Marcos JC, Duarte A, Berbotto GA, Scherbarth H, Marques CD, Onetti L, Saurit V, Souza AW, Velozo E, Catoggio LJ, Neira O, Burgos PI, Ramirez LA, Molina JF, De La Torre IG, Silvari\u00f1o R, Manni JA, Dur\u00e1n-Barrag\u00e1n S, Vil\u00e1 LM, Fortin PR, Calvo-Al\u00e9n J, Santos MJ, Portela M, Esteva-Spinetti MH, Weisman M, Acevedo EM, Segami MI, Gentiletti SB, Rold\u00e1n J, Navarro I, Gonzalez E, Liu JM, Karlson EW, Costenbader KH, Wolfe F, Alarc\u00f3n GS. Validation of the Spanish, Portuguese and French versions of the Lupus Damage Index questionnaire: data from North and South America, Spain and Portugal. Lupus. 2009 Oct;18(12):1033-52.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM, Alarc\u00f3n GS, McGwin G, Edberg JC, Petri M, Ramsey-Goldman R, Reveille JD, Kimberly RP; PROFILE Study Group. Factors associated with arterial vascular events in PROFILE: a Multiethnic Lupus Cohort. Lupus. 2009 Oct;18(11):958-65.<\/p>\n<p style=\"text-align: justify;\">Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, J\u00f6nsen A, Bengtsson AA, Rantap\u00e4\u00e4-Dahlqvist S, Baechler EC, Brown EE, Alarc\u00f3n GS, Edberg JC, Ramsey-Goldman R, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Kimberly RP, Manzi S, Petri MA, Lee A, Gregersen PK, Seldin MF, R\u00f6nnblom L, Criswell LA, Syv\u00e4nen AC, Behrens TW, Graham RR. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet. 2009 Nov;41(11):1228-33.<\/p>\n<p style=\"text-align: justify;\">Burgos PI, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Peripheral vascular damage in systemic lupus erythematosus: data from LUMINA, a large multi-ethnic U.S. cohort (LXIX). Lupus. 2009 Dec;18(14):1303-8.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2008<\/span><\/h2>\n<p style=\"text-align: justify;\">Apte M, McGwin G Jr, Vil\u00e1 LM, Kaslow RA, Alarc\u00f3n GS, Reveille JD; LUMINA Study Group. Associated factors and impact of myocarditis in patients with SLE from LUMINA, a multiethnic US cohort (LV). Rheumatology (Oxford) 2008 Mar; 47(3):362-7.<\/p>\n<p style=\"text-align: justify;\">Molina MJ, Mayor AM, Franco AE, Morell CA, L\u00f3pez MA, Vil\u00e1 LM. Utilization of health services and prescription patterns among lupus patients followed by primary care physicians and rheumatologists in Puerto Rico. Ethn Dis 2008 Spring; 18(2 Suppl 2):S2-205-10.<\/p>\n<p style=\"text-align: justify;\">Rodriguez VE, Costas PJ, Vazquez M, Alvarez G, Perez-Kraft G, Climent C, Nazario CM. Prevalence of spondyloarthropathy in Puerto Rican patients with inflammatory bowel disease. Ethn Dis 2008 Spring; 18(2 Suppl 2):S2-225-9.<\/p>\n<p style=\"text-align: justify;\">Andrade R, Sanchez ML, Alarc\u00f3n GS, Fessler BJ, Fern\u00e1ndez M, Bertoli AM, Apte M, Vil\u00e1 LM, Arango AM, Reveille JD; LUMINA Study Group. Adverse pregnancy outcomes in women with systemic lupus erythematosus from a multiethnic US cohort: LUMINA (LVI) Clin Exp Rheumatol. 2008 Mar-Apr; 26(2):268-74.<\/p>\n<p style=\"text-align: justify;\">Ramsey-Goldman R, Alarc\u00f3n GS, McGwin G, Petri M, Vil\u00e1 LM, Edberg JC, Reveille JD, Kimberly RP; Profile Study Group. Time to seizure occurrence and damage in PROFILE, a multi-ethnic systemic lupus erythematosus cohort. Lupus 2008; 17(3):177-84.<\/p>\n<p style=\"text-align: justify;\">Negr\u00f3n AM, Molina MJ, Mayor AM, Rodr\u00edguez VE, Vil\u00e1 LM. Factors associated with metabolic syndrome in patients with systemic lupus erythematosus from Puerto Rico. Lupus 2008; 17(4):348-54.<\/p>\n<p style=\"text-align: justify;\">Tucker LB, Uribe AG, Fern\u00e1ndez M, Vil\u00e1 LM, McGwin G, Apte M, Fessler BJ, Bastian HM, Reveille JD, Alarc\u00f3n GS. Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case-control study within LUMINA, a multiethnic US cohort (LUMINA LVII). Lupus 2008; 17(4):314-22.<\/p>\n<p style=\"text-align: justify;\">Kelly JA, Kelley JM, Kaufman KM, Kilpatrick J, Bruner GR, Merrill JT, James JA, Frank SG, Reams E, Brown EE, Gibson AW, Marion MC, Langefeld CD, Li QZ, Karp DR, Wakeland EK, Petri M, Ramsey-Goldman R, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS, Kimberly RP, Harley JB, Edberg JC. Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans. Genes Immun 2008 Apr; 9(3):187-94.<\/p>\n<p style=\"text-align: justify;\">Andrade RM, Alarc\u00f3n GS, Gonz\u00e1lez LA, Fern\u00e1ndez M, Apte M, Vil\u00e1 LM, McGwin G Jr, Reveille JD; LUMINA Study Group. Seizures in patients with systemic lupus erythematosus: data from LUMINA, a multiethnic cohort (LUMINA LIV). Ann Rheum Dis 2008 Jun; 67(6):829-34.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA study group. Systemic lupus erythaematosus in a multiethnic US cohort (LUMINA) LIII: disease expression and outcome in acute onset lupus. Ann Rheum Dis 2008 Apr; 67(4):500-4.<\/p>\n<p style=\"text-align: justify;\">Galanter J, Choudhry S, Eng C, Nazario S, Rodr\u00edguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodr\u00edguez-Cintr\u00f3n W, Avila PC, Burchard EG. ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med. 2008 Jun 1; 177(11):1194-200.<\/p>\n<p style=\"text-align: justify;\">Mary CL, L\u00f3pez-Malpica F, D\u00edaz AM. Analysis of cross-reactivity between group 1 allergens from mites. PR Health Sci J. 2008 Jun; 27(2):163-70.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, McGwin G Jr, Andrade R, Bastian HM, Fessler BJ, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS; LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort, LUMINA (XLIX): preliminary evaluation of the impact of statins on disease activity. J Clin Rheumatol 2008 Jun; 14(3):178-80.<\/p>\n<p style=\"text-align: justify;\">Dur\u00e1n-Barrag\u00e1n S, McGwin G Jr, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA (LIX): a multiethnic US cohort. Angiotensin-converting enzyme inhibitors delay the occurrence of renal involvement and are associated with a decreased risk of disease activity in patients with systemic lupus erythematosus-results from LUMINA (LIX): a multiethnic US cohort. Rheumatology (Oxford). 2008 Jul; 47(7):1093-6.<\/p>\n<p style=\"text-align: justify;\">Scofield RH, Bruner GR, Namjou B, Kimberly RP, Ramsey-Goldman R, Petri M, Reveille JD, Alarc\u00f3n GS, Vil\u00e1 LM, Reid J, Harris B, Li S, Kelly JA, Harley JB. Klinefelter\u2019s syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome. Arthritis Rheum. 2008 Aug; 58(8):2511-7.<\/p>\n<p style=\"text-align: justify;\">Gonz\u00e1lez LA, McGwin G Jr, Dur\u00e1n S, Pons-Estel GJ, Apte M, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA Study Group. Predictors of premature gonadal failure in patients with systemic lupus erythematosus. Results from LUMINA, a multiethnic US cohort (LUMINA LVIII). Ann Rheum Dis. 2008 Aug; 67(8):1170-3.<\/p>\n<p style=\"text-align: justify;\">Dur\u00e1n S, Apte M, Alarc\u00f3n GS, Marion MC, Edberg JC, Kimberly RP, Zhang J, Langefeld CD, Vil\u00e1 LM, Reveille JD; Lumina Study Group. Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort. Arthritis Rheum. 2008 Sep15;59(9):1332-40.<\/p>\n<p style=\"text-align: justify;\">Mart\u00ednez D. Jaccoud\u2019s arthropathy revisited. Bol Asoc Med P R. 2008 Jul-Sep; 100(3):51-3.<\/p>\n<p style=\"text-align: justify;\">Rodriguez VE, Costas P. Systemic lupus erythematosus presenting as acute iceric hepatitis: case report. Bol Asoc Med P R. 2008 Jul-Sep; 100(3):54-7.<\/p>\n<p style=\"text-align: justify;\">Colacioppo-Saavedra R, Rodr\u00edguez-Castro J, L\u00f3pez JE, Mayor AM. Outcomes after heart valve replacement surgery at the Cardiovascular Center of Puerto Rico and the Caribbean. P R Health Sci J. 2008 Dec; 27(4):368-72.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): LXI. Value of C-reactive protein as a marker of disease activity and damage. J Rheumatol. 2008 Dec;35(12):2355-8.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM. Personalized Medicine for Systemic Lupus Erythematosus: A New Challenge for the Near Future. In: Systemic Lupus Erythematosus Research Trends. Editor: Tomas I. Seward, Nova Science Publishers, Inc., Hauppauge, New York, USA 2008.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2007<\/span><\/h2>\n<p style=\"text-align: justify;\">Bertoli AM, Fern\u00e1ndez M, Alarc\u00f3n GS, Vil\u00e1 LM, Reveille JD. Systemic lupus erythematosus in a multiethnic U.S. cohort LUMINA (XLI): Factors predictive of self-reported work disability. Ann Rheum Dis. 2007; 66:12-7.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1 LM, Molina MJ, Mayor AM, Cruz JJ, R\u00edos-Olivares E, R\u00edos Z. Association of serum MIP 1\u03b1, MIP-1\u03b2 and RANTES with clinical manifestations, disease activity and damage accrual in systemic lupus erythematosus. Clin Rheumatol 2007; 26:718-22.<\/p>\n<p style=\"text-align: justify;\">Col\u00f3n M, Mart\u00ednez DA. Clinical remission of systemic lupus erythematosus after human immunodeficiency virus infection. P R Health Sci J. 2007 Mar; 26(1):79-81.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Calvo-Al\u00e9n J, Andrade R, McGwin G, Jr., Vil\u00e1 LM, John D. Reveille JD, Alarc\u00f3n GS. The LUMINA Cohort as a model for the study of ethnic disparities in systemic lupus erythematosus. Arthritis Rheum (Arthritis Care Res) 2007; 57:576-84.<\/p>\n<p style=\"text-align: justify;\">Bastian HM, Alarc\u00f3n GS, Roseman JM. McGwin G, Jr., Vil\u00e1 LM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic U.S. cohort (LUMINA): Factors associated of new or worsening proteinuria. Rheumatology (Oxford). 2007; 46:683-9.<\/p>\n<p style=\"text-align: justify;\">Andrade RM, Alarc\u00f3n GS, Fern\u00e1ndez M, Apte M, Vil\u00e1 LM, Reveille JD. Accelerated damage accrual among men with systemic lupus erythematosus patients: Results from LUMINA, a multiethnic cohort. Arthritis Rheum 2007; 56:622-630.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Andrade RM, Fessler BJ, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Systemic lupus erythematosus in a multiethnic U.S. cohort (LUMINA): The significance of thrombocytopenia as a poor prognostic factor. Arthritis Rheum 2007; 56:614-621.<\/p>\n<p style=\"text-align: justify;\">Chaiamnuay S, Bertoli AM, Roseman JM, McGwin G Jr, Apte M, Vil\u00e1 LM, Duran S, Reveille JD, Alarc\u00f3n GS. African American and Hispanic ethnicities, renal involvement and obesity predispose to hypertension in Systemic Lupus Erythematosus: Results from LUMINA, a multiethnic cohort. (LUMINA XLV). Ann Rheum Dis 2007; 66: 618-22.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM. Font YM. Nadal A, Vil\u00e1 LM. Treatment of Giant Cell Arteritis Using Induction Therapy with High-dose Glucocorticoids: A double-blind, Placebo-controlled, Randomized Prospective Clinical trial. Comment on an Article by Mazlumzadeh M. et al. Arthritis Rheum 2007; 56:1723.<\/p>\n<p style=\"text-align: justify;\">Chaiamnuay S, Bertoli AM, Fern\u00e1ndez M, Apte M, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS for the LUMINA Study Group. The Impact of Increased Body Mass Index on Systemic Lupus Erythematosus: Data from LUMINA, a Multiethnic Cohort. J Clin Rheumatol 2007; 13:128-133.<\/p>\n<p style=\"text-align: justify;\">Molina MJ, Mayor AM, Franco AE, Morell CA, L\u00f3pez MA, Vil\u00e1 LM. Prevalence of systemic lupus erythematosus and associated comorbidities in Puerto Rico. J Clin Rheumatol 2007; 13: 202-4.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1 LM, Molina MJ. Chronic anemia and thrombocytosis as the initial presentation of Still\u2019s disease in an elderly patient. Gerontology 2007; 53:289-292.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM, Apte M,Fessler BJ, Bastian HM, Reveille JD, Alarc\u00f3n GS. Systemic lupus erythematosus in a multiethnic US cohort LUMINA XLVIII: Factors predictive of pulmonary damage. Lupus 2007; 16: 410-7.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, McGwin G, Jr., Bertoli AM, Fessler BJ, Calvo-Al\u00e9n J, Bastian HM, Vil\u00e1 LM, Reveille JD, for the LUMINA Study Group. Effect of hydroxychloroquine in the survival of patients with systemic lupus erythematosus. Data from LUMINA, a multiethnic US cohort (LUMINA L). Ann Rheum Dis 2007; 66: 1168-72.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Alarc\u00f3n GS, McGwin G Jr, S\u00e1nchez ML, Apte M, Vil\u00e1 LM, Reveille JD LUMINA STUDY GROUP .Using the Short Form 6D, as an overall measure of health, to predict damage accrual and mortality in patients with systemic lupus erythematosus: XLVII,results from a multiethnic US cohort. Arthritis Rheum. 2007 Jul 30; 57:986-992.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Alarc\u00f3n GS, Vil\u00e1 LM, Reveille JD. Reply. Arthritis Rheum 2007 Jul 30; 56:2812.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Vil\u00e1 LM, Apte M,Fessler BJ, Bastian HM, Reveille JD, Alarc\u00f3n GS. Systemic Lupus Erythematosus in a Multiethnic U.S. Cohort LUMINA LI: Anemia as a Predictor of Disease Activity and Damage Accrual Rheumatology (Oxford) 2007; 46: 1471-6.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Calvo-Al\u00e9n J, Bertoli AM, Bastian HM, Fessler BJ, McGwin G Jr, Reveille JD, Vil\u00e1 LM, Alarc\u00f3n GS; for the LUMINA Study Group. Systemic Lupus Erythematosus in a Multiethnic US Cohort (LUMINA L II): Relationship between Vascular Events and the Use of Hormone Replacement Therapy in Postmenopausal Women. J Clin Rheumatol 2007 Oct; 13(5):261-265.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2006<\/span><\/h2>\n<p style=\"text-align: justify;\">Bertoli AM, Fern\u00e1ndez M, Calvo-Al\u00e9n J, Bastian HM, Fessler BJ, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic U.S. cohort LUMINA XXXI: Factors associated with patients being lost to follow-up. Lupus 2006 15: 19-25.<\/p>\n<p style=\"text-align: justify;\">Bertoli A, Alarc\u00f3n GS, McGwin G, Jr., Fern\u00e1ndez M, Bastian HM, Fessler BJ, Vil\u00e1 LM, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic U.S. cohort LUMINA XXVII: Factors predictive of a decline to low levels of disease activity. Lupus 2006; 15: 13-8.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, Bastian HM, Beasley TM, Roseman JM, Tan FK, Fessler BJ, Vil\u00e1 LM, McGwin G, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multi-ethnic cohort (LUMINA) XXXII: Contributions of admixture and socioeconomic status to renal involvement. Lupus 2006; 15: 26-31.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Fern\u00e1ndez M, Bastian HM, Fessler BJ, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic U.S. cohort LUMINA XXXIII: Clinical features, course and outcome of patients with late-onset disease. Arthritis Rheum, 2006; 54: 1580-7.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Fern\u00e1ndez M, McGwin G Jr., Tan,FK, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Systemic lupus erythematosus in a multiethnic us cohort (LUMINA) XLIII: Influence of mannose binding lectin exon 1 polymorphisms in disease manifestations, course and outcome. Arthritis Rheum 2006; 54:1703-4.<\/p>\n<p style=\"text-align: justify;\">Calvo-Al\u00e9n J, McGwin G, Jr., Roseman JM, Toloza SMA, Bastian HM, Fernandez M, Fessler BJ, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXIV. Cytotoxic therapy is an additional risk factor for the development of osteonecrosis in lupus patients. Results of a nested matched case-control. Ann Rheum Dis 2006; 65:785-90.<\/p>\n<p style=\"text-align: justify;\">Calvo-Al\u00e9n J, Alarc\u00f3n GS, Toloza SMA, McGwin G, Jr., Bastian HM, Vil\u00e1 LM, Fessler BJ, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic U.S. cohort: XXXIV. Deficient mannose-binding lectin exon 1 polymorphisms are associated with cerebrovascular but not with other arterial thrombotic events. Arthritis Rheum 2006; 54:1940-5.<\/p>\n<p style=\"text-align: justify;\">Bertoli AM, Fernandez M, McGwin G Jr, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS Association of antioxidized low-density lipoprotein antibodies with vascular arterial events and renal manifestations in systemic lupus erythematosus patients: comment on the article by Frostegard et al. Arthritis Rheum 2006; 54:2035-6.<\/p>\n<p style=\"text-align: justify;\">Col\u00f3n-Soto M, Peredo RA, Vil\u00e1 LM. Systemic lupus erythematosus after mesotherapy with acetyl-l-carnitine. J Clin Rheumatol 2006;12:261-2.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1 LM, Alarc\u00f3n GS, McGwin G, Jr., Bastian HM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic cohort (LUMINA) XXXVII: Association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity and damage accrual. Arthritis Rheum (Arthritis Care Res) 2006; 55:799-806.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, Calvo-Al\u00e9n J, McGwin G, Uribe AG, Toloza SM, Roseman J, Fernandez M, Fessler BJ, Vil\u00e1 L, Ahn C, Tan FK, Reveille JD. Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time. Ann Rheum Dis 2006;65:1168-74.<\/p>\n<p style=\"text-align: justify;\">R\u00edos-Olivares E, Vil\u00e1 LM, Reyes JC, Rodr\u00edguez JW, Pag\u00e1n NO, Marrero A, Col\u00f3n HM, R\u00edos-Orraca ZM, Boukli NM, Robles RR. Impaired cytokine production and suppressed proliferation activity in HCV-infected cocaine and heroin (\u201cspeedball\u201d) users. Drug Alcohol Depend 2006; 85: 236-43.<\/p>\n<p style=\"text-align: justify;\">Andrade RM, McGwin Jr. G, Alarc\u00f3n GS, Sanchez ML, Bertoli AM, Fessler BJ, Apte M, Arango AM, Bastian HM, Vil\u00e1 LM, Reveille JD. Predictors of post-partum damage accrual: Data from LUMINA (XXXVIII), a Multiethnic Cohort. Rheumatology (Oxford) 2006;45:1380-4.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1 LM, Molina MJ, Mayor AM, Peredo RA, Santaella ML, Vil\u00e1 S. Clinical and prognostic value of autoantibodies in Puerto Ricans with systemic lupus erythematosus. Lupus 2006; 15:892-8.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, McGwin G, Jr., Petri M, Ramsey-Goldman R, Fessler BJ, Vil\u00e1 LM, Edberg JC, Reveille JD, Kimberly RP, for the PROFILE Study Group. Time to renal disease and end-stage renal disease in PROFILE, a multiethnic lupus cohort. PLoS Med 2006 Oct; 3(10):e396.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, McGwin G Jr, Bertoli AM, Calvo-Al\u00e9n J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS; LUMINA Study Group. Discontinuation rate and factors predictive of the use of hydroxychloroquine in LUMINA, a multiethnic US cohort (LUMINA XL). Lupus. 2006;15:700-4.<\/p>\n<p style=\"text-align: justify;\">Rodr\u00edguez VE, Gonz\u00e1lez-Par\u00e9s E, Rivera C. Clinical manifestations and vascular events in patients with lupus, anticardiolipin antibodies and Raynaud\u2019s phenomenon. PR Health Sci J 2006; 5:307-314.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2005<\/span><\/h2>\n<p style=\"text-align: justify;\">Santaella ML, Font I and Disdier, O. Common variable immunodeficiency: Experience in Puerto Rico.PR Health Sci J 2005: 24(1): 7.<\/p>\n<p style=\"text-align: justify;\">Santaella ML, Peredo R and Disdier, O. IgA deficiency: clinical correlates with IgG subclass and mannan-binding lectin (MBL) deficiencies. PR Health Sci J 2005; 24(2):107.<\/p>\n<p style=\"text-align: justify;\">Mart\u00ednez D, Su\u00e1rez S. Early diagnosis and treatment of Churg-Strauss syndrome might prevent life\u2013threatening complications of vasculitis. Bol Asoc Med PR 2005; 97:69-74.<\/p>\n<p style=\"text-align: justify;\">Calvo-Al\u00e9n J, Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS. Effect of ethnicity in disease activity. (Letter) J Rheumatol 2005; 32:962.<\/p>\n<p style=\"text-align: justify;\">Fessler BJ, Alarc\u00f3n GS, McGwin G, Jr., Roseman JM, Bastian HM, Friedman AW, Baethge BA, Vil\u00e1 L, Reveille JD, for the LUMINA Study Group: Systemic lupus erythematosus in a multiethnic cohort. (LUMINA) XVI: Hydroxychloroquine usage is associated with a lower risk of damage accrual. Arthritis Rheum, 2005; 52:1473-80.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez M, Calvo-Al\u00e9n J, Alarc\u00f3n GS, Roseman JM, Bastian HM, Fessler BJ, Vil\u00e1 LM, McGwin G, Jr, Reveille JD. Systemic Lupus Erythematosus in a Multiethnic U.S. Cohort LUMINA XXVI: Disease activity, damage accrual and vascular events in pre and post-menopausal women. Arthritis Rheum 2005; 52:1655-64.<\/p>\n<p style=\"text-align: justify;\">R\u00edos G. Retrospective Review of the Clinical manifestations and Outcomes in Puerto Ricans with Idiopathic Inflammatory Myopathies, J Clin Rheumatol 2005; 11 (3): 153-156.<\/p>\n<p style=\"text-align: justify;\">Calvo-Al\u00e9n J, Toloza S, Fern\u00e1ndez M, Bastian HM, Fessler BJ, Roseman JM, McGwin G, Jr., Vil\u00e1 LM, Reveille JD, Alarc\u00f3n GS, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XXV: Smoking, older age and glucocorticoid use are risk factors for the occurrence of venous thrombosis in lupus patients. Arthritis Rheum 2005; 52:2060-8.<\/p>\n<p style=\"text-align: justify;\">Szalai AJ, Alarc\u00f3n GS, Calvo-Al\u00e9n J, Toloza SMA, McCrory MA, Edberg JC, McGwin G, Jr., Bastian HM, Fessler BJ, Vil\u00e1 LM, Kimberly RP, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XXX: Association between C-reactive protein (CRP) gene polymorphisms and vascular events. Rheumatology (Oxford) 2005; 44: 864-8.<\/p>\n<p style=\"text-align: justify;\">Ho KT, Ahn CW, Alarc\u00f3n GS, Baethge BA, Tan FK, Roseman J, Bastian HM, Fessler BJ, McGwin G, Jr., Vil\u00e1 LM, Calvo-Al\u00e9n J, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXVIII. Factors predictive of thrombotic events. Rheumatology (Oxford) 2005; 44:1303-7.<\/p>\n<p style=\"text-align: justify;\">Vil\u00e1 LM, Alarc\u00f3n GS, McGwin G, Jr., Bastian HM, Fessler BJ, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic cohort (LUMINA) XXIX: Elevation of erythrocyte sedimentation rate is associated with disease activity and damage accrual. J Rheumatology 2005; 32:2150-5.<\/p>\n<p style=\"text-align: justify;\">Peredo R, Vil\u00e1 S, Go\u00f1i M, Col\u00f3n E, R\u00edos\u2013Sol\u00e1 G. Reactive Thrombocytosis. An Early Manifestation of Takayasu Arteritis. J Clin Rheumatol 2005; 11: 270-3.<\/p>\n<p style=\"text-align: justify;\">Santaella ML, Cox PR, Col\u00f3n M, Ramos C, Disdier OM. Rheumatologic manifestations in patients with selected immunodeficiencies evaluated at the University Hospital. P R Health Sci J 2005; 24: 191-5.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, Beasly TM, Roseman JM, McGwin G Jr, Fessler BJ, Bastian HM, Vil\u00e1 LM, Tan F, Reveille JD. Ethnic disparities in health and disease: the need to account for ancestral admixture when estimating the genetic contribution to both (LUMINA XXVI). Lupus 2005; 14: 867-8.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2004<\/span><\/h2>\n<p style=\"text-align: justify;\">Mart\u00ednez A, Vil\u00e1 LM, R\u00edos-Oliveras E. Predominance of CD4+ T cells and Th2 cytokines in the pericardial fluid of a dermatomyositis patient with cardiac tamponade. Clin Exp Rheumatol 2004; 22(1):135.<\/p>\n<p style=\"text-align: justify;\">Santaella ML, Font I and Disdier, O. Comparison of oral nicotinamide adenine dinucleotide (NADH) versusconventional therapy for chronic fatigue syndrome. PR Health Sci J 2004; 23(2): 89.<\/p>\n<p style=\"text-align: justify;\">Alarc\u00f3n GS, McGwin G, Jr., Uribe A, Friedman AW, Roseman JM, Fessler BJ, Bastian H M, Baethge BA, Vil\u00e1 LM, Reveille JD, for the LUMINA Study Group. Systemic lupus erythematosus in a multiethnic lupus cohort (LUMINA), XVII: Predictors of self-reported health-related quality of life early in the disease course. Arthritis Rheum (Arthritis Care Res). 2004;51:465-474.<\/p>\n<p style=\"text-align: justify;\">Alarcon GS, McGwin G Jr, Roseman JM, Uribe A, Fessler BJ, Bastian HM, Friedman AW, Baethge B, Vila LM, Reveille JD.Systemic lupus erythematosus in three ethnic groups. XIX. Natural history of the accrual of the American College of Rheumatology criteria prior to the occurrence of criteria diagnosis. Arthritis Rheum. 2004; 51:609-15.<\/p>\n<p style=\"text-align: justify;\">Toloza SMA, Roseman JM, Alarc\u00f3n GS, McGwin G Jr., Uribe AG, Fessler BJ, Bastian HM, Vil\u00e1 LM, Reveille JD for the LUMINA Study Group: Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XXII: Predictors of time to the occurrence of damage for the first time. Arthritis Rheum 2004; 50:3177-3186.<\/p>\n<p style=\"text-align: justify;\">Uribe AG, Vil\u00e1 LM, McGwin G, Jr., Sanchez ML, Reveille JD, Alarc\u00f3n GS: The Systemic Lupus Activity Measure-Revised, the Mexican Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and a Modified SLEDAI-2K are adequate instruments to measure disease activity in systemic lupus erythematosus. J Rheumatol. 2004; 31:1934-40.<\/p>\n<p style=\"text-align: justify;\">Toloza SMA, Uribe AG, Alarc\u00f3n GS, McGwin G, Agee BS, Fessler BJ, Bastian HM, Vil\u00e1 LM, Roseman JM, Reveille JD for theLUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XXIII: Baseline predictors of vascular events. Arthritis Rheum 2004; 50: 3947-57.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2003<\/span><\/h2>\n<p style=\"text-align: justify;\">Mayor AM, Vil\u00e1 LM, De La Cruz M, G\u00f3mez R. Impact of Managed Care on Clinical Outcome of Systemic Lupus Erythematosus in Puerto Rico. J Clin Rheumatol 2003; 9: 25-32.<\/p>\n<p style=\"text-align: justify;\">Mayor AM, Vil\u00e1 LM. Gender differences in a cohort of Puerto Ricans with systemic lupus erythematosus. Cell Mol Biol (Noisy-le-grand) 2003; 49:1339-44.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">2000<\/span><\/h2>\n<p style=\"text-align: justify;\">Rodr\u00edguez V, Gonz\u00e1lez-Par\u00e9s EN. Mortality study in Puerto Ricans with systemic lupus erythematosus. P Rico Health Sci J 2000; 19:335-9<\/p>\n<p style=\"text-align: justify;\">Carmona CI, Gonz\u00e1lez-Par\u00e9s EN. The prevalence of antiphospholipid syndrome in systemic lupus erythematosus patients at the University Hospital. P R Health Sci J 2000; 19:341-4.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1988<\/span><\/h2>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Par\u00e9s, EN, Senior J, Rubio C, Torres EA. Prevalence of upper gastrointestinal mucosal abnormalities at a Rheumatology clinic. Bol Asoc Med PR 1988; 80:241.<\/p>\n<p style=\"text-align: justify;\">Fern\u00e1ndez C. Outcome of benign hyperglobulinemic purpura. Bol Asoc Med PR 1988; 12:455.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1987<\/span><\/h2>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Par\u00e9s EN, L\u00f3pez-M\u00e9ndez A. Takayasu arteritis in Puerto Rico: a clinical study. Bol Asoc Med PR 1987; 79:230.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1976<\/span><\/h2>\n<p style=\"text-align: justify;\">Lergier J, Gonz\u00e1lez-Par\u00e9s EN, Mart\u00ednez R, Fern\u00e1ndez C. DNA antigen binding avidity and nephritis in SLE. Bol Asoc Med PR 1976; 68:311.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1974<\/span><\/h2>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Par\u00e9s EN, Costas R, D\u00edaz Rivera RS. Myocardial infarction-report of 115 cases. Bol Asoc Med PR 1974; 66:122.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1973<\/span><\/h2>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Par\u00e9s EN, Franco AE, De la Cruz S, Ramos Morales F, Gonz\u00e1lez-Alcover R, M\u00e9ndez-Bryan R. False positive latex in a tropical area. J Chronic Dis 1973: 26:31-8.<\/p>\n<p style=\"text-align: justify;\">Ravry M, Rubio C, Gonz\u00e1lez E. Prevalence of hepatitis-associated antigen (HAA) in collagen disorders. Bol Asoc Med P R. 1973; 65:60-2.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1970<\/span><\/h2>\n<p style=\"text-align: justify;\">Horta EO, Gonz\u00e1lez-Par\u00e9s EN, P\u00e9rez-Santiago E. The relationship of idiopathic thrombocytopenic purpura with SLE. Bol Asoc Med PR 1970; 62: 41-51.<\/p>\n<p style=\"text-align: justify;\">Brooks CD, Schmid FR, Biundo J, Blau S, Gonzalez-Alcover R, Gowans JD, Hurd E, Partridge RE, Tarpley EL. Ibuprofen and aspirin in the treatment of rheumatoid arthritis. A cooperative double-blind trial. Rheumatol Phys Med 1970;10:Suppl 10:48-63.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1968<\/span><\/h2>\n<p style=\"text-align: justify;\">Franco AE, Gonz\u00e1lez-Par\u00e9s EN, M\u00e9ndez-Bryan R. Uric acid levels in the population with rheumatic complaints. Bol Asoc Med PR 1968; 60:479-85.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1967<\/span><\/h2>\n<p style=\"text-align: justify;\">Franco A, Gonz\u00e1lez Par\u00e9s EN. Juvenile rheumatoid arthritis. A review. Bol Asoc Med P R 1967; 59:414-20.<\/p>\n<p style=\"text-align: justify;\">Neff JM, Morris L, Gonzalez-Alcover R, Coleman PH, Lyss SB, Negron H. Dengue fever in a Puerto Rican community. Am J Epidemiol 1967; 86(1):162-84.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1966<\/span><\/h2>\n<p style=\"text-align: justify;\">Gonz\u00e1lez EN, Rothfield NF. Immunoglobulin class and pattern of nuclear fluorescence in systemic lupus erythematosus. N Engl J Med 1966; 274:1333-8.<\/p>\n<h2 style=\"text-align: justify;\"><span style=\"color: #800000;\">1964<\/span><\/h2>\n<p style=\"text-align: justify;\">M\u00e9ndez-Bryan R, Gonz\u00e1lez-Alcover R, Roger L. Rheumatoid arthritis: prevalence in a tropical area. Arthritis Rheum 1964; 7:171-6.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;] 2025 Serrano-Arroyo L, Gonz\u00e1lez-Mel\u00e9ndez A, R\u00edos-Rivera R, Rodr\u00edguez-Gonz\u00e1lez V, Vil\u00e1 LM. Impact of SARS-CoV-2 pre-delta\/delta and omicron variants on clinical outcomes in a systemic lupus erythematosus cohort from Puerto Rico. Lupus. 2025 Apr;34(4):415-424. L\u00f3pez LA, Vil\u00e1 LM. Dual Autoimmunity: A Case Report of the Sequential Development of Systemic Lupus Erythematosus in a Patient&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":63,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-67","page","type-page","status-publish","hentry","description-off"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/pages\/67","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/comments?post=67"}],"version-history":[{"count":4,"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/pages\/67\/revisions"}],"predecessor-version":[{"id":1601,"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/pages\/67\/revisions\/1601"}],"up":[{"embeddable":true,"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/pages\/63"}],"wp:attachment":[{"href":"https:\/\/md.rcm.upr.edu\/rai\/wp-json\/wp\/v2\/media?parent=67"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}