Dr. Sylvette Nazario Jiménez

Assistant Professor
Dr. sylvette Ayala

Contact Info

  • University of Puerto Rico
    Medical Sciences Campus
    School of Medicine
    Associate Deanship for Academic Affairs, A-866
    San Juan, PR 00936
  • 787-758-2525, Ext. 1825

Education

  • August 1983- May 1987 MD 2 2 University of Puerto Rico Medical School San Juan, Puerto Rico Janet Glasgow Award, Alpha Omega Alpha
  • August 1980- May 1983 BS Major in Biology, Minor in Math University of Puerto Rico, Rio Piedras Campus Rio Piedras, Puerto Rico

ACADEMIC POSITIONS

Allergy Immunology Program Director and Chief Section Allergy-Immunology University of Puerto Rico Medical School
Associate Professor UPR Medical School

RESEARCH INTEREST

Principal Investigator for Subcontract PREPARE (PeRson EmPowered Asthma RElief) PCORI Asthma Project in Puerto Rico (2016- present

PROFESSIONAL MEMBERSHIP

Alpha Omega Alpha

American College of Physicians

American Academy Allergy, Asthma and Immunology, Member

American College Allergy, Asthma and Immunology, Fellow

Asociación Puertorriqueña de Médicos Alergistas

Clinical Immunologfy Society, Member.

PUBLICATIONS

Israel E, Cardet JC, Carroll JK, Fuhlbrigge AL, She L, Rockhold FW, Maher NE, Fagan

M, Forth VE, Yawn BP, Arias Hernandez P, Kruse JM, Manning BK, Rodriguez-Louis J, Shields

JB, Ericson B, Colon-Moya AD, Madison S, Coyne-Beasley T, Hammer GM, Kaplan BM, Rand

CS, Robles J, Thompson O, Wechsler ME, Wisnivesky JP, McKee MD, Jariwala SP, Jerschow

E, Busse PJ, Kaelber DC, Nazario S, Hernandez ML, Apter AJ, Chang KL, Pinto-Plata V,

Stranges PM, Hurley LP, Trevor J, Casale TB, Chupp G, Riley IL, Shenoy K, Pasarica M,

Calderon-Candelario RA, Tapp H, Baydur A, Pace WD. Reliever-Triggered Inhaled

Glucocorticoid in Black and Latinx Adults with Asthma. N Engl J Med. 2022 Feb 26.

 

Benitez-Ortiz Y, Nazario S. Tense Bullae as a Rare Skin Manifestation of Hereditary

Angioedema. J Allergy Clin Immunol Pract. 2020 Nov-Dec;8(10):3586.

 

Coppola-Fasick G, Nazario S. Recurrent otitis externa owing to allergic contact

dermatitis to topical medications. Ann Allergy Asthma Immunol. 2020 Nov;125(5):616-617.

 

Israel E, Cardet JC, Carroll JK, Fuhlbrigge AL, Pace WD, Maher NE, She L, Rockhold

FW, Fagan M, Forth VE, Hernandez PA, Manning BK, Rodriguez-Louis J, Shields JB, Coyne

Beasley T, Kaplan BM, Rand CS, Morales-Cosme W, Wechsler ME, Wisnivesky JP, White M,

Yawn BP, McKee MD, Busse PJ, Kaelber DC, Nazario S, Hernandez ML, Apter AJ, Chang KL,

Pinto-Plata V, Stranges PM, Hurley LP, Trevor J, Casale TB, Chupp G, Riley IL, Shenoy K,

Pasarica M, Calderon-Candelario RA, Tapp H, Baydur A. A randomized, open-label, pragmatic study to assess reliever-triggered inhaled corticosteroid in African American/Black and Hispanic/Latinx adults with asthma: Design and methods of the PREPARE trial. Contemp Clin Trials. 2021 Feb; 101:106246

 

Cardet JC, Busse PJ, Carroll JK, Casale TB, Coyne-Beasley T, Dixon-Williams S, Fagan

M, Forth VE, Fuhlbrigge AL, Hernandez ML, Kaelber D, Kaplan B, Lorenzi M, Madison S, Maher NE, Majewski K, Manning B, McKee MD, Nazario S, Pace WD, Pencina MJ, Rand CS,

Rodriguez-Louis J, She L, Shields J, Teng JE, Wechsler ME, Wisnivesky JP, Yawn BP, Israel E.

Adherence to adding inhaled corticosteroids to rescue therapy in a pragmatic trial with adults with asthma: A pilot study. Ann Allergy Asthma Immunol. 2020 May;124(5):487-493

 

Watts-Oquendo ET, Coppola-Fasick G, Arroyo-Flores E, Soto-Salgado M, Nazario S. Effect of topical pramoxine hydrochloride on discomfort, wheal and flare associated with epicutaneous allergy test.  Ann Allergy Asthma Immunol. 2019 Jun;122(6):652-653.

 

Cosme-Blanco W, Arce-Ayala Y, Malinow I, Nazario S. Primary and Secondary Environmental Control Measures for Allergic Diseases in Allergy and Asthma: the Basics to Best Practice, Massoud et la Springer, 2018. https://doi.org/10.1007/978-3-319-58726-4

 

Perez-Lopez CJ, Arroyo E, Rodriguez M, Ortiz D, Nazario S. Disseminated Mycobacterium avium intracellulare leading to protein-losing enteropathy in an elderly man with idiopathic CD4 lymphocytopenia.Ann Allergy Asthma Immunol. 2017 Oct;119(4):390-391

 

Cosme-Blanco W, Arroyo-Flores E, Nazario S. Zika virus infection as a trigger of atopic dermatitis.Ann Allergy Asthma Immunol. 2017 Nov;119(5):459-460.

 

Mario G. Ortiz-Martínez, Orquídea Frías-Belén, Sylvette Nazario-Jiménez, María López Quintero, Rosa I. Rodríguez-Cotto, Braulio D. Jiménez-Vélez. A case–control study of innate

immunity pathway gene polymorphisms in Puerto Ricans reveals association of toll-like receptor 2 +596 variant with asthma. BMC Pulm Med. 2016 Aug 5;16(1):112. PMID:27495363

 

Rodríguez-Roa M, Nazario S, Ramos C. A 47-year-old man with tongue swelling. Allergy Asthma Proc. 2016 Jul;37(4):340-2. PMID:27401321

 

Malinow I, Rivera-Santiago R, López-Malpica F, Zaragoza R, Velázquez V, Acantilado C, Rodríguez R, Rivera A, López-Almodóvar C, Nazario S. Association of the Asthma Control Test with peak flow measures in a population in Puerto Rico. P R Health Sci J. 2014 Sep;33(3):122-8 PMID: 25244881

 

Calderón E, Méndez J, Nazario S. Anaphylaxis diagnosis and treatment at an

emergency department in Puerto Rico. P R Health Sci J. 2013 Dec; 32(4):170-4 PMID:

24397213

 

Sylvette Nazario, Rafael Zaragoza, Vylma Velázquez, Gilberto Ramos-Valencia,  Carmen Acantilado, Ray Rodríguez,  Ángel Rivera,  María M. Alvarez,  Carlos López Almodóvar, Fernando López-Malpica, Allergen sensitivity in a Puerto Rican cohort:  mites, insects and pets. P R Health Sci J. 2012 Mar;31(1):24-8. PMID:22432405

 

Félix E Rivera-Mariani , Sylvette Nazario-Jiménez, Fernando López-Malpica and Benjamín Bolaños-Rosero. (2011) Skin test reactivity of allergic subjects to basidiomycetes’ crude extracts in a tropical environment. Med Mycol. 2011 Nov;49(8):887-91. PMID:21506892

 

Félix E Rivera-Mariani , Sylvette Nazario-Jiménez, Fernando López-Malpica and Benjamín Bolaños-Rosero. (2011)  Sensitization to Airborne Ascospores, Basidiospores, and Fungal Fragments in Allergic Rhinitis and Asthmatic Subjects in San Juan, Puerto Rico. Int Arch Allergy Immunol  155(4):322-34. PMID:21346362

 

Sylvette Nazario, Carmen Acantilado, María Álvarez, Carlos López-Almodóvar, Gilberto Ramos-Valencia, Angel Rivera, Ray Rodríguez, Vylma Velázquez, Rafael Zaragoza, Fernando

López-Malpica.  (2011) Allergist role in asthma care in Puerto Rico. Bol Asoc Med P R, 103 (1):18-21

 

Ramos-Romey C, López-Malpica F, Nazario S, Jiménez-Velázquez IZ. Urticaria in the elderly. Bol Asoc Med P R. 2008 Jul-Sep;100(3):32-5

 

Nazario S. Asthma among Puerto Ricans.Bol Asoc Med P R. 2008 Jul-Sep;100(3):28-31.

 

Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG. ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med. 2008 Jun 1;177(11):1194-200. Epub 2008 Feb 28.

 

Naqvi M, Thyne S, Choudhry S, Tsai HJ, Navarro D, Castro RA, Nazario S, Rodriguez Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, LeNoir M, Avila PC, Rodriguez-Cintron W, Burchard EG. Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthma. J Asthma. 2007 Oct;44(8):639-48.

 

Naqvi M, Choudhry S, Tsai HJ, Thyne S, Navarro D, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, Lenoir M, Avila PC, Burchard EG. Association between IgE levels and asthma severity among African American,

Mexican, and Puerto Rican patients with asthma. J Allergy Clin Immunol. 2007 Jul;120(1):137-43. Epub 2007 May 11.

 

Tsai YJ, Choudhry S, Kho J, Beckman K, Tsai HJ, Navarro D, Matallana H, Castro RA, Lilly CM, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Salas J, Chapela R, Watson HG, Meade K, Avila PC, Rodriguez-Cintron W, LeNoir M, Burchard EG; Genetics of Asthma in Latino Americans Study; Study of African Americans, Asthma, Genes and Environments Investigators. The PTGDR gene is not associated with asthma in 3 ethnically diverse populations. J Allergy Clin Immunol. 2006 Dec;118(6):1242-8. Epub 2006 Sep 26.

 

Choudhry S, Burchard EG, Borrell LN, Tang H, Gomez I, Naqvi M, Nazario S, Torres A, Casal J, Martinez-Cruzado JC, Ziv E, Avila PC, Rodriguez-Cintron W, Risch NJ.  Ancestry environment interactions and asthma risk among Puerto Ricans.  Am J Respir Crit Care Med.

2006 Nov 15;174(10):1088-93. Epub 2006 Sep 14.

 

Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG; Genetics of Asthma in Latino Americans GALA Study.  Population stratification confounds genetic association studies among Latinos.  Hum Genet. 2006 Jan;118(5):652-64. Epub 2005 Nov 8.

 

Salari K, Choudhry S, Tang H, Naqvi M, Lind D, Avila PC, Coyle NE, Ung N, Nazario S, Casal J, Torres-Palacios A, Clark S, Phong A, Gomez I, Matallana H, Pérez-Stable EJ, Shriver MD, Kwok PY, Sheppard D, Rodriguez-Cintron W, Risch NJ, Burchard EG, Ziv E. Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol. 2005 Jul;29(1):76-86.

 

Choudhry S, Avila PC, Nazario S, Ung N, Kho J, Rodriguez-Santana JR, Casal J, Tsai HJ, Torres A, Ziv E, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Castro RA, Selman M, Weiss ST, Ford JG, Drazen JM, Rodriguez-Cintron W, Chapela R, Silverman EK, Burchard EG. CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma.  Am J Respir Crit Care Med. 2005 Jul 15;172(2):173-82. Epub 2005 May 5.

 

Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, Gomez I, Fagan

JK, Salas J, Clark S, Lilly C, Matallana H, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Drazen JM, Rodriguez-Cintron W, Silverman EK, Burchard EG. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans

with asthma. Am J Respir Crit Care Med. 2005 Mar 15;171(6):563-70. Epub 2004 Nov 19.

 

Nazario S, Casal JR, Torres-Palacios A, Rodriguez W, Delamater AM, Applegate EB, Piedimonte G, Wanner A. Parent-reported asthma in Puerto Rican children. Pediatr Pulmonol. 2004 May;37(5):453-60.

 

Burchard EG, Avila PC, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Ziv E, Castro R, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Rodriguez Cintron W, Drazen JM, Silverman EK; Genetics of Asthma in Latino Americans (GALA) Study. Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma.  Am J Respir Crit Care Med. 2004 Feb 1;169(3):386-92. Epub 2003 Nov 14.

 

Lind DL, Choudhry S, Ung N, Ziv E, Avila PC, Salari K, Ha C, Lovins EG, Coyle NE, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Matallana H, Lilly CM, Salas J, Selman M, Boushey HA, Weiss ST, Chapela R, Ford JG, Rodriguez-Cintron W, Silverman EK, Sheppard D, Kwok PY, González Burchard E. ADAM33 is not associated with asthma in Puerto Rican or Mexican populations.  Am J Respir Crit Care Med. 2003 Dec 1;168(11):1312-6. Epub 2003 Sep 4

 

Ortiz A, Martínez M, Torres A, Casal J, Rodríguez W, Nazario S.  Predictors of smoking cessation success. P R Health Sci J. 2003 Jun;22(2):173-7.

 

Nazario S; Das S; de Silva AM; Deponte K; Marcantonio N; Anderson JF; Fish D; Fikrig E; Kantor FS. Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity. American Journal of Tropical Medicine and Hygiene 01-JUN-1998; 58(6): 780-5 Alicea E; Casal J; Nazario S; Rodríguez W Asthma knowledge among internal medicine residents. Puerto Rico Health Sciences Journal- 01-MAR-1999; 18(1): 19-21

Grant: 

Principal Investigator for Subcontract PREPARE (PeRson EmPowered Asthma RElief)

PCORI Asthma Project in Puerto Rico (2016- present)