Dr. Brenda L. Deliz Roldán

Associate Professor

Contact Info

  • University District Hospital
    Neurology Section, 5th Floor
    School of Medicine
    San Juan, PR 00936
  • 787-754-0101, Ext. 2516

Education

INTERNSHIP: University District Hospital, Medical Center, 2000-01

RESIDENCY: Neurology, University District Hospital, Medical Center, 2001-04

FELLOWSHIP: Neuromuscular Diseases University District Hospital, Medical Center, 2004-05

SPECIALTY: Neurology

SUBSPECIALTY: Neuromuscular Diseases

ACADEMIC POSITIONS

Associate Professor, UPR, School of Medicine, 2014-present

Assistant Professor, UPR School of Medicine, 2005

RESEARCH EXPERIENCES

Clinical Trial of Insulin-like-Growth Factor-I (IGF-I) in Amyotrophic Lateral Sclerosis (ALS)

The purpose of this study is to determine if insulin-like growth factor-I (IGF-I) slows the progressive weakness in amyotrophic lateral sclerosis (ALS) patients.

Role: Puerto Rico Site Co-Investigator Dates: 2005-2008 Study status: Completed

PI170503: Clinical Trial of Coenzyme QIO and Prednisone in Duchenne Muscular Dystrophy

This study will help determine if CoQ10 and prednisone, alone and as a combination decrease the decline in cardiopulmonary and skeletal muscle function that occurs in the wheelchair confined phase of DMD. Role: Puerto Rico Site Co-Investigator Dates: 2005-2009 Study status: Closed

Neuropsychological Performance, Biochemical and Microstructural Changes at Early Stages of Multiple Sclerosis

The purpose of the study is to determine if there is a correlation among Cognitive function with newer neuro-imaging Techniques (MRS) that could help to detect changes at an earlier phase. Role: Co- Investigator Study Dates: 2006-2010 Study status: Completed

UCD0305: Longitudinal Study of the Relationship between Impairment, Activity Limitation, Participation and

Quality of Life in Persons with Confirmed Duchenne Muscular Dystrophy

The primary goal of this study is to establish the largest long-term assessment of people with Duchenne muscular dystrophy (DMD) between the ages of 2 and 30 years.

Role: Puerto Rico Site Co-investigator Date 2008-Present Study status: Active

Seroprevalence of NMO/AQP4-lgG in a Puerto Rican patient cohort with inflammatory CNS disorders: a Mayo Ethiopian collaborative study

This study will help to determine if NMO/AQP4 lgG is present in serum of patients with inflammatory disease other than in patients with Neuromyelitis Optica.

Role: Puerto Rico Site Co-investigator Dates: 2009- Present Study status: Active

Neuropsychiatric Manifestations in a cohort of Relapsing Remitting Multiple Sclerosis

The study will aim to assess the presence of neuropsychiatric symptoms as depression, anxiety, and fatigue in a group of patients with relapsing remitting multiple sclerosis in the Multiple Sclerosis Clinics. A correlation between these symptoms with the level of the disability of the patient will also be studied. Role: Co- Investigator Dates: 2010-2011 Study Status: Completed

The Impact of Fatigue and Depression on Cognitive Functioning in Patients with Multiple Sclerosis- A Pilot

Study Neuropsychiatric Manifestations in a cohort of Relapsing Remitting Multiple Sclerosis

Role: Co- Investigator Dates: 2012-Present

Study Status: Active

PUBLICATIONS

Please list books first, then full articlest and lastly the abstracts:

San Miguel, L.s., Deliz, B., Trefz, K. (2011). Multiple Sclerosis. C. Noogle , R. Dean (Eds.), The Encyclopedia of Neuropsychological Disorders (pp. 487-499). New York: Springer Publishing.

Otero, M. , Bosques, M., Soto, R., Deliz, B., Bertran, J., Vargas, P. (2011). Tetanus is still present in the

21 st century: Case report and review of literature. Publication from Puerto Rican Medical Association, 41 47,

Pegoraro, E., Hoffman, E.P., Piva, L., Gavassini, B., CINRG group- Deliz, B., et al.(201 1). SPP 1 genotype is determinant of disease severity in Duchenne muscular dystrophy. Neurology, 76, 219-225.

San Miguel, L. , Deliz, B. (2010). Clinical and Neuropsychological Symptoms in Multiple Sclerosis. Puerto Rican Journal of Neurosciences, 7(1), 17-32.

Vazquez, Y. , Deliz, B., Gonzalez, N., Carlo, J. Mitochondrial Gastrointestinal Encephalomyopathy (MNGIE) without Gastrointestinal Manifestations: a case report. MDA Clinical Conference 2012. March 7.

(Abstract)

Vazquez, Y., Deliz, B. , Gonzalez, N., Carlo, J. , et al. Optimizing Referrals to Muscular Dystrophy Association Clinics through an Educational Program for Primary Care Physicians. MDA Clinical Conference 2012. March 7. (Abstract)

Deliz, B. , Schenk, C., San Miguel, L. , Alfonso, G.,et al. Neuropsychological Performance and Biochemical

MRS changes in as and RRMS. Neurology  1): POI .227. (Abstract)

Vazquez, Y., Deliz, B. , Pardo,S., Alfonso, G. Distinct Mutations of SGCA and CAPN3 of Limb Girdle Muscular Dystrophy within the same Puerto Rican Family. Muscle and Nerve 2011; 44(4):623. (Abstract)

Vazquez, Y., Luciano, C., Deliz, B., Carlo, J., Alfonso, G., et al. Distal and Proximal Thermal and Pain Perception in Human Immunodeficiency Virus Sensory Neuropathy. Muscle and Nerve 2011; 44(4):694 (Abstract)