Dr. Valerie Wojna Muñiz

Professor

Contact Info

  • University of Puerto Rico
    School of Medicine
    Section of Neurology, 5th floor
    University District Hospital
    San Juan, PR 00936
  • 787-754-0101, Ext. 2507

Education

Degree: M.D. UPR, School of Medicine, 1984

Degree: B.A. –(Math), UPR, Río Piedras Campus, 1980

INTERSHIP: UPR, University District Hospital, 1984-85

RESIDENCY: Adult Neurology, UPR, University District Hospital, 1985-88

FELLOWSHIP: Clinical Neurophysiology, UPR, University District Hospital, 1988-90

SPECIALTY: Neurology

SUBSPECIALTY: Clinical Neurophysiology

ACADEMIC APPOINTMENTS

Professor, UPR, Medical Sciences Campus, 2001-present

Associate Professor, UPR Medical Sciences Campus, 1996-2001

Assistant Professor, UPR, Medical Sciences Campus, 1990-96

Clinical Instructor, UPR, Medical Sciences Campus, 1988-90

Clinical Resident, UPR, Medical Sciences Campus, 1988

RESEARCH EXPERIENCES

Estrogen as a neuroprotector factor in HIV Dementia (PI), UPR, MSC, COPENIC pilot funds, 2001-02

MRS and HIV Dementia in Puerto Rican Women (PI), RCMI Clinical Research Infrastructure Initiative- pilot funds, 2002-03

Oxidative Markers in HIV Dementia (PI), RCMI Clinical Research Infrastructure Initiative – pilot funds, 2003-04

Functional & Structural Correlates of Neurocognitive Impairment in HIV (Algaze PI, Wojna Co-PI), RCMI Clinical Research Infrastructure Initiative – pilot funds, 2006-07

Pathophysiology of HIV Dementia in Women, NIH/NINDS, 2004-11

Monocyte Immunity and HIV-induced Dementia (Kriselburg PD/Melendez PI/Wojna Co-Inv), NIH/NINDS, 2006-08

Hispanic-Latino NeuroAIDS Clinical Core (Kriselburg PD/Wojna co-PI), NIH/NINDS, 2006-11

Molecular Basis for Neuronal Nicotinic Receptor Upregulation: Potential Implications in HAD (Kraiselburg PD/Lasaldel PI/Wojna co-Inv), NIH/NINDS, 2006-11

Quality of Life Outcomes in Neurological Disorders (Cella PI/Wojna Site PI), NIH Tool Box, 2007-10

Spatial Learning and Memory in HIV infection (Acevedo PI/Wojna co-PI), RCMI Clinical Research Infrastructure Initiative – pilot funds, 2008-09

PUBLICATIONS

BOOK CHAPTER:

Melendez, L.M., Luciano, C. Mayo-Santana R., Wojna, V. Ethnicity and Neuro-AIDS Conditions in the HAART Era. In “The Spectrum of NeuroAIDS Disorders: Pathophysiology, Diagnosis, and Treatment”. ASM Press, 2009

ORIGINAL RESEARCH MANUSCRIPTS

Wojna V, Guerrero L, Guzmán J, Cotto M. Effect of flumazenil on electroencephalographic patterns induced by midazolam. P R Health Sci J. 2000 Dec;19(4):353-6. PubMed PMID: 11293887.

Luo X, Carlson KA, Wojna V, Mayo R, Biskup TM, et al. Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment. Neurology. 2003 Jun 24;60(12):1931-7. PubMed PMID: 12821735.

Wojna V, Carlson KA, Luo X, Mayo R, Meléndez LM, et al. Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study. J Neurovirol. 2004;10 Suppl 1:74-81. PubMed PMID: 14982743.

Wojna V, Skolasky RL, Hechavarría R, Mayo R, Selnes O, et al. Prevalence of human immunodeficiency virus-associated cognitive impairment in a group of Hispanic women at risk for neurological impairment. J Neurovirol. 2006 Oct;12(5):356-64. PubMed PMID: 17065128.

Nieves DM, Plaud M, Wojna V, Skolasky R, Meléndez LM. Characterization of peripheral blood human immunodeficiency virus isolates from Hispanic women with cognitive impairment. J Neurovirol. 2007 Aug;13(4):315-27. PubMed PMID: 17849315; PubMed Central PMCID: PMC2925199.

Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, …, Wojna V. Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007 Oct 30;69(18):1789-99. PubMed PMID: 17914061.

Rozek W, Ricardo-Dukelow M, Holloway S, Gendelman HE, Wojna V, et al. Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment. J Proteome Res. 2007 Nov;6(11):4189-99. PubMed PMID: 17929958.

Wojna V, Skolasky RL, McArthur JC, Maldonado E, Hechavarria R, et al. Spanish validation of the HIV dementia scale in women. AIDS Patient Care STDS. 2007 Dec;21(12):930-41. PubMed PMID: 18154490.

Wojna V, Robles L, Skolasky RL, Mayo R, Selnes O, et al. Associations of cigarette smoking with viral immune and cognitive function in human immunodeficiency virus-seropositive women. J Neurovirol. 2007 Dec;13(6):561-8. PubMed PMID: 18097887.

Laspiur JP, Anderson ER, Ciborowski P, Wojna V, Rozek W, et al. CSF proteomic fingerprints for HIV-associated cognitive impairment. J Neuroimmunol. 2007 Dec;192(1-2):157-70. PubMed PMID: 17950469; PubMed Central PMCID: PMC2248223.