Welcome to the website of the Department of Physiology and Biophysics of the School of Medicine-University of Puerto Rico. The department was directed by Dr. Nelson Escobales since 1997 and since December 2019 by Dr. Annabell C. Segarra. The department has been developed into a center for modern physiological research with particular emphasis in neurophysiology, cell and molecular physiology, genetics, exercise physiology, and cardiovascular research. As part of this program, there is also faculty interested in membrane physiology and biophysics. Each laboratory is using state-of-the-art molecular-biology and cellular approaches to address important physiological questions. Research in the department ranges from the cellular and molecular to the organ and system level physiology.

Our graduate students, post- doctoral fellows and faculty are working to unravel the mechanisms of brain and nerve development, learning and memory, cellular communication, membrane function, hormone action, synaptic transmission, and vascular function. In doing so, they are helping to uncover the causes and mechanisms of human disease, including asthma, heart failure, hypertension, infertility, and diabetes. In addition, research conducted by our faculty and students will contribute to understand the basis of drug addiction, spinal cord injury, and aging.

In addition to their research, the faculty also pride themselves on their medical, dental, and graduate teaching. At present, we teach Medical and Dental Physiology, and all faculty members participate in the Graduate Physiology Program as well as many others at the University of Puerto Rico-Biology Intercampus Program. Special emphasis is given to the integrative nature of physiology. The department is located in the east wing of the sixth floor of the Medical Sciences building. Faculty laboratories are well-equipped for research and training, along with several shared facilities supported by the university and RCMI. We welcome applications from persons interested in our graduate program and postdoctoral fellow positions.


Administrator:                                                                 Secretaries:                                                                                                                                                       Laboratory Assistant:

                    Luis Carrasquillo                                                                    Iris D. Rivera                                                              Amarilis Torres                                             Iván L. Vázquez





                                                                                                                                               Research Assistants:



                       Miriam Castro                                                               Hilda Osorio                                                        Ioannis M. Torres                                                      María E. Santiago